KEGG   Homo sapiens (human): 51111
Entry
51111             CDS       T01001                                 
Symbol
KMT5B, CGI-85, CGI85, MRD51, SUV420H1
Name
(RefSeq) lysine methyltransferase 5B
  KO
K11429  [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00310  Lysine degradation
hsa01100  Metabolic pathways
Disease
H00773  Autosomal dominant intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    51111 (KMT5B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    51111 (KMT5B)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.362  [histone H4]-N-methyl-L-lysine20 N-methyltransferase
     51111 (KMT5B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     51111 (KMT5B)
SSDB
Motif
Pfam: SET
Other DBs
NCBI-GeneID: 51111
NCBI-ProteinID: NP_060105
OMIM: 610881
HGNC: 24283
Ensembl: ENSG00000110066
UniProt: Q4FZB7
Structure
Position
11:complement(68154863..68213648)
AA seq 885 aa
MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF
EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS
HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE
HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN
MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG
EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR
LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA
SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP
KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR
SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA
KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG
VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL
RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ
LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD
YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA
NT seq 2658 nt   +upstreamnt  +downstreamnt
atgaagtggttgggagaatccaagaacatggtggtgaatggcaggagaaatggaggcaag
ttgtctaatgaccatcagcagaatcaatcaaaattacagcacacggggaaggacaccctg
aaggctggcaaaaatgcagtcgagaggaggtcgaacagatgtaatggtaactcgggattt
gaaggacagagtcgctatgtaccatcctctggaatgtccgccaaggaactctgtgaaaat
gatgacctagcaaccagtttggttcttgatccctatttaggttttcaaacacacaaaatg
aatactagcgcctttccttcgaggagctcaaggcatttttcaaaatctgacagtttttct
cacaacaaccctgtgagatttaggcctattaaaggaaggcaggaagaactaaaggaagta
attgaacgttttaagaaagatgaacacttggagaaagccttcaaatgtttgacttcaggc
gaatgggcacggcactattttctcaacaagaataaaatgcaggagaaattattcaaagaa
catgtatttatttatttgcgaatgtttgcaactgacagtggatttgaaatattgccatgt
aatagatactcatcagaacaaaatggagccaaaatagttgcaacaaaagagtggaaacga
aatgacaaaatagaattactggtgggttgtattgccgaactttcagaaattgaggagaac
atgctacttagacatggagaaaacgacttcagtgtcatgtactccacaaggaaaaactgt
gctcaactctggctgggtcctgctgcgtttataaaccatgattgcagacctaattgtaag
tttgtgtcaactggtcgagatacagcatgtgtgaaggctctaagagacattgaacctgga
gaagaaatttcttgttattatggagatgggttctttggagaaaataatgagttctgcgag
tgttacacttgcgaaagacggggcactggtgcttttaaatccagagtgggactgcctgcg
cctgctcctgttatcaatagcaaatatggactcagagaaacagataaacgtttaaatagg
cttaaaaagttaggtgacagcagcaaaaattcagacagtcaatctgtcagctctaacact
gatgcagataccactcaggaaaaaaacaatgcaacttctaaccgaaaatcttcagttggc
gtaaaaaagaatagcaagagcagaacgttaacgaggcaatctatgtcaagaattccagct
tcttccaactctacctcatctaagctaactcatataaataattccagggtaccaaagaaa
ctgaagaagcctgcaaagcctttactttcaaagataaaattgagaaatcattgcaagcgg
ctggagcaaaagaatgcttcaagaaaactcgaaatgggaaacttagtactgaaagagcct
aaagtagttctgtataaaaatttgcccattaaaaaagataaggagccagagggaccagcc
caagccgcagttgccagcgggtgcttgactagacacgcggcgagagaacacagacagaat
cctgtgagaggtgctcattcgcagggggagagctcgccctgcacctacataactcggcgg
tcagtgaggacaagaacaaatctgaaggaggcctctgacatcaagcttgaaccaaatacg
ttgaatggctataaaagcagtgtgacggaaccttgccccgacagtggtgaacagctgcag
ccagctcctgtgctgcaggaggaagaactggctcatgagactgcacaaaaaggggaggca
aagtgtcataagagtgacacaggcatgtccaaaaagaagtcacgacaaggaaaacttgtg
aaacagtttgcaaaaatagaggaatctactccagtgcacgattctcctggaaaagacgac
gcggtaccagatttgatgggtccccattctgaccagggtgagcacagtggcactgtgggc
gtgcctgtgagctacacagactgtgctccttcacccgtcggttgttcagttgtgacatca
gatagcttcaaaacaaaagacagctttagaactgcaaaaagtaaaaagaagaggcgaatc
acaaggtatgatgcacagttaatcctagaaaataactctgggattcccaaattgactctt
cgtaggcgtcatgatagcagcagcaaaacaaatgaccaagagaatgatggaatgaactct
tccaaaataagcatcaagttaagcaaagaccatgacaacgataacaatctctatgtagca
aagcttaataatggatttaactcaggatcaggcagtagttctacaaaattaaaaatccag
ctaaaacgagatgaggaaaatagggggtcttatacagaggggcttcatgaaaatggggtg
tgctgcagtgatcctctttctctcttggagtctcgaatggaggtggatgactatagtcag
tatgaggaagaaagtacagatgattcctcctcttctgagggcgatgaagaggaggatgac
tatgatgatgactttgaagacgattttattcctcttcctccagctaagcgcttgaggtta
atagttggaaaagactctatagatattgacatttcttcaaggagaagagaagatcagtct
ttaaggcttaatgcctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (34)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (32)   
DNA sequence (83)   
   RefSeq(nuc) (35)   
   GenBank (24)   
   EMBL (24)   
3D Structure (7)   
   PDB (7)   
Protein domain (1)   
   Pfam (1)   
All databases (154)   

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