KEGG   Homo sapiens (human): 51449
Entry
51449             CDS       T01001                                 
Symbol
PCYOX1, PCL1
Name
(RefSeq) prenylcysteine oxidase 1
  KO
K05906  prenylcysteine oxidase / farnesylcysteine lyase [EC:1.8.3.5 1.8.3.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00900  Terpenoid backbone biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    51449 (PCYOX1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.3  With oxygen as acceptor
    1.8.3.5  prenylcysteine oxidase
     51449 (PCYOX1)
    1.8.3.6  farnesylcysteine lyase
     51449 (PCYOX1)
SSDB
Motif
Pfam: Prenylcys_lyase NAD_binding_8 Amino_oxidase DAO Pyr_redox_2 NAD_binding_9 Thi4 Trp_halogenase
Other DBs
NCBI-GeneID: 51449
NCBI-ProteinID: NP_057381
OMIM: 610995
HGNC: 20588
Ensembl: ENSG00000116005
UniProt: Q9UHG3
Position
2:70257915..70281185
AA seq 505 aa
MGRVVAELVSSLLGLWLLLCSCGCPEGAELRAPPDKIAIIGAGIGGTSAAYYLRQKFGKD
VKIDLFEREEVGGRLATMMVQGQEYEAGGSVIHPLNLHMKRFVKDLGLSAVQASGGLLGI
YNGETLVFEESNWFIINVIKLVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVE
KLLHALGGDDFLGMLNRTLLETLQKAGFSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSL
SCSDSGLWAVEGGNKLVCSGLLQASKSNLISGSVMYIEEKTKTKYTGNPTKMYEVVYQIG
TETRSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNTSIFSSR
PIDKFGLNTVLTTDNSDLFINSIGIVPSVREKEDPEPSTDGTYVWKIFSQETLTKAQILK
LFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYYLNGIECAASAMEMSAIAAHNAALL
AYHRWNGHTDMIDQDGLYEKLKTEL
NT seq 1518 nt   +upstreamnt  +downstreamnt
atggggcgcgtcgtcgcggagctcgtctcctcgctgctggggttgtggctgttgctgtgc
agctgcggatgccccgagggcgccgagctgcgtgctccgccagataaaatcgcgattatt
ggagccggaattggtggcacttcagcagcctattacctgcggcagaaatttgggaaagat
gtgaagatagacctgtttgaaagagaagaggtcgggggccgcctggctaccatgatggtg
caggggcaagaatacgaggcaggaggttctgtcatccatcctttaaatctgcacatgaaa
cgttttgtcaaagacctgggtctctctgctgttcaggcctctggtggcctactggggata
tataatggagagactctggtatttgaggagagcaactggttcataattaacgtgattaaa
ttagtttggcgctatggatttcaatccctccgtatgcacatgtgggtagaggacgtgtta
gacaagttcatgaggatctaccgctaccagtctcatgactatgccttcagtagtgtcgaa
aaattacttcatgctctaggaggagatgacttccttggaatgcttaatcgaacacttctt
gaaaccttgcaaaaggccggcttttctgagaagttcctcaatgaaatgattgctcctgtt
atgagggtcaattatggccaaagcacggacatcaatgcctttgtgggggcggtgtcactg
tcctgttctgattctggcctttgggcagtagaaggtggcaataaacttgtttgctcaggg
cttctgcaggcatccaaaagcaatcttatatctggctcagtaatgtacatcgaggagaaa
acaaagaccaagtacacaggaaatccaacaaagatgtatgaagtggtctaccaaattgga
actgagactcgttcagacttctatgacatcgtcttggtggccactccgttgaatcgaaaa
atgtcgaatattacttttctcaactttgatcctccaattgaggaattccatcaatattat
caacatatagtgacaactttagttaagggggaattgaatacatctatctttagctctaga
cccatagataaatttggccttaatacagttttaaccactgataattcagatttgttcatt
aacagtattgggattgtgccctctgtgagagaaaaggaagatcctgagccatcaacagat
ggaacatatgtttggaagatcttttcccaagaaactcttactaaagcacaaattttaaag
ctctttctgtcctatgattatgctgtgaagaagccatggcttgcatatcctcactataag
cccccggagaaatgcccctctatcattctccatgatcgactttattacctcaatggcata
gagtgtgcagcaagtgccatggagatgagtgccattgcagcccacaacgctgcactcctt
gcctatcaccgctggaacgggcacacagacatgattgatcaggatggcttatatgagaaa
cttaaaactgaactatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (2)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (29)   
   RefSeq(nuc) (3)   
   GenBank (13)   
   EMBL (13)   
Protein domain (8)   
   Pfam (8)   
All databases (72)   

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