KEGG   Homo sapiens (human): 5210
Entry
5210              CDS       T01001                                 
Symbol
PFKFB4
Name
(RefSeq) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
  KO
K19030  6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00051  Fructose and mannose metabolism
hsa01100  Metabolic pathways
hsa04152  AMPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    5210 (PFKFB4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    5210 (PFKFB4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.105  6-phosphofructo-2-kinase
     5210 (PFKFB4)
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.46  fructose-2,6-bisphosphate 2-phosphatase
     5210 (PFKFB4)
SSDB
Motif
Pfam: 6PF2K His_Phos_1 AAA_33 Prefoldin KTI12 His_Phos_2 AAA_18 Zeta_toxin
Other DBs
NCBI-GeneID: 5210
NCBI-ProteinID: NP_004558
OMIM: 605320
HGNC: 8875
Ensembl: ENSG00000114268
UniProt: Q16877
Position
3:complement(48517684..48563136)
AA seq 469 aa
MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT
RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYV
NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
NT seq 1410 nt   +upstreamnt  +downstreamnt
atggcgtccccacgggaattgacacagaaccccctgaagaagatctggatgccatacagc
aatgggcggcccgctctgcacgcttgccagcgcggtgtgtgcatgaccaactgcccaact
ctcattgtcatggtgggcctgcccgccaggggcaagacctacatctccaagaagctgact
cgatacctgaactggattggtgtgcccactcgggagttcaatgttggccagtatcgccgg
gacgtggtcaagacctacaaatcttttgaattttttctccccgacaatgaagagggcctg
aaaatcaggaagcagtgtgccctggcagccctccgtgacgtccggcggttccttagtgag
gaggggggacatgtggcggtttttgatgccacaaacaccacccgagaacggagagcgacc
atctttaattttggagaacagaatggctacaagaccttttttgtcgagtccatctgtgtg
gatcctgaggtcatagctgccaacatcgtgcaagtgaaactgggcagccctgactatgtc
aaccgcgacagtgatgaggctacggaggacttcatgaggcgcattgagtgctatgagaac
tcctacgagtcgctagatgaggacctggatagggacctgtcctatatcaagatcatggat
gtgggccagagctacgtggtgaaccgtgtggctgaccacatccagagccgcatcgtatat
tacctcatgaacatccacgtgaccccccgctccatctacctctgccggcacggggagagc
gagctcaacctcaagggccggattggcggggacccaggactgtcccctcggggcagggag
tttgccaagagtctagcccagttcatcagtgaccaaaatatcaaggatctgaaggtctgg
acaagccagatgaagaggacaatccagacggctgaggcactgggtgtgccctatgaacag
tggaaggtcctcaacgagatcgatgcgggcgtctgtgaggaaatgacctacgaggaaatt
caggataattatccactggagttcgccctgcgggaccaggacaagtaccggtaccggtac
cctaaaggggagtcctacgaggacctggtccagagactggagcctgtcatcatggagctg
gagaggcaagagaatgtgctggtcatctgccaccaggctgtgatgcgctgcctgctggcc
tacttcctcgacaaggcagcagaacagctgccctacctcaagtgtccgctgcacacagtc
ctgaagctgactcctgtggcatatggttgtaaagtggagtccatattcctgaacgtggct
gctgtgaacacgcaccgggacaggcctcagaacgtggacatctcaagacctccagaggaa
gcccttgtcacggtgcctgctcaccagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (2)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (30)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (28)   
DNA sequence (54)   
   RefSeq(nuc) (28)   
   GenBank (13)   
   EMBL (13)   
Protein domain (8)   
   Pfam (8)   
All databases (115)   

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