KEGG   Homo sapiens (human): 54014
Entry
54014             CDS       T01001                                 
Symbol
BRWD1, C21orf107, CILD51, DCAF19, N143, WDR9, WRD9
Name
(RefSeq) bromodomain and WD repeat domain containing 1
  KO
K11798  bromodomain and WD repeat domain containing protein 1/3
Organism
hsa  Homo sapiens (human)
Disease
H00564  Primary ciliary dyskinesia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    54014 (BRWD1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     54014 (BRWD1)
SSDB
Motif
Pfam: WD40 Bromodomain ANAPC4_WD40 NBCH_WD40
Other DBs
NCBI-GeneID: 54014
NCBI-ProteinID: NP_061836
OMIM: 617824
HGNC: 12760
Ensembl: ENSG00000185658
UniProt: Q9NSI6
Structure
Position
21:complement(39184176..39321212)
AA seq 2320 aa
MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHN
RSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRH
TVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHR
RILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYEN
TMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF
WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEK
IAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSE
EERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFD
SRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHL
LIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH
PTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIR
QLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQMH
QNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQL
SHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHETSCDQSEGSGSS
EEDEWRSDRKSESYSESSSDSSSRYSDWTADAGINLQPPLRTSCRRRITRFCSSSEDEIS
TENLSPPKRRRKRKKENKPKKENLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQ
MGDEVIYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGIRYEVGPPTLC
CLKLAFIDPATGKLMDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQSCDRFRSIIDDA
WWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISV
TTDELEKLLYKPQAGEWGQKSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTV
VAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKITDQLLKF
IKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNYVESNWKK
QCKELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCK
DIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRFKQ
RQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYLGTHKTSAGISSGV
TSGDSSDSAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARES
SSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKRVYLSDSDNNSLETGEILKA
RAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVARKKLLHNSED
EQSLKSEIEEEELKDENQLLPVSSSHTAQSNVDESENRDSESESDLRVARKNWHANGYKS
HTPAPSKTKFLKIESSEEDSKSHDSDHACNRTAGPSTSVQKLKAESISEEADSEPGRSGG
RKYNTFHKNASFFKKTKILSDSEDSESEEQDREDGKCHKMEMNPISGNLNCDPIAMSQCS
SDHGCETDLDSDDDKIEKPNNFMKDSASQDNGLSRKISRKRVCSSDSDSSLQVVKKSSKA
RTGLLRITRRCAATAANKIKLMSDVEDVSLENVHTRSKNGRKKPLHLACTTAKKKLSDCE
GSVHCEVPSEQYACEGKPPDPDSEGSTKVLSQALNGDSDSEDMLNSEHKHRHTNIHKIDA
PSKRKSSSVTSSGEDSKSHIPGSETDRTFSSESTLAQKATAENNFEVELNYGLRRWNGRR
LRTYGKAPFSKTKVIHDSQETAEKEVKRKRSHPELENVKISETTGNSKFRPDTSSKSSDL
GSVTESDIDCTDNTKTKRRKTKGKAKVVRKEFVPRDREPNTKVRTCMHNQKDAVQMPSET
LKAKMVPEKVPRRCATVAANKIKIMSNLKETISGPENVWIRKSSRKLPHRNASAAAKKKL
LNVYKEDDTTINSESEKELEDINRKMLFLRGFRSWKENAQ
NT seq 6963 nt   +upstreamnt  +downstreamnt
atggcggagccgtcgtccgcccgacgcccggtgcctctcatcgagtcggagctgtacttc
cttatcgcccggtacctatcggcgggcccgtgtcggagagcggcccaggtgctggtgcag
gagctggagcagtaccagttgttgccgaagagattggactgggagggcaacgagcacaac
aggagctacgaggagttggtcttgtccaataagcatgtggctcctgatcatcttttgcaa
atctgccagcgcatcggtcctatgttggataaagaaattccacccagtatttcaagagtc
acttctttacttggtgcaggaaggcagtctttgctacgtacagcaaaagactgcaggcac
acagtttggaagggctctgcctttgctgctcttcatagaggaagacctcctgaaatgcca
gtgaattatggttccccaccaaatcttgtggagatacatcgaggaaaacaactcacaggg
tgttccacttttagtacagcatttccaggaactatgtatcagcatataaaaatgcacaga
aggattctcggacatctatctgctgtttactgtgtagcatttgataggacaggacataga
atctttacaggttcagatgactgtttggtaaagatttggtcaacacataatggccgcttg
ttatctacattaagaggtcattctgcagaaatttcagatatggcagtaaactatgagaat
acaatgattgctgcggggagctgtgataaaattattagagtgtggtgcttgagaacttgt
gccccagttgctgtgctccaaggacacacaggatcaattacatctttacagtttagcccg
atggccaaaggctctcaaagatacatggtttccactggtgctgatgggacagtttgcttt
tggcaatgggatttagaatccttaaaatttagcccacgtcccctgaagttcactgaaaag
cctaggccaggcgttcaaatgctttgttcttcttttagtgttggtggtatgtttttagcc
acaggtagtactgatcatgtaatcagaatgtattttttgggttttgaagcacccgaaaaa
atcgcagaacttgaaagccacactgataaagtagatagtatccaattttgtaacaatggt
gatcggttcctaagtggtagcagagatggaacagcacggatttggagatttgagcagtta
gaatggaggagcattttattggatatggctaccagaatctcaggggacttatcttccgaa
gaggaaaggtttatgaaacctaaagtaacaatgatagcttggaatcaaaatgatagcatt
gttgtcacagctgtgaatgatcatgtcctcaaagtgtggaattcttacactggacaactg
cttcataacttaatgggacatgctgatgaagtatttgttctggagacacatccctttgat
tccagaattatgttatctgcaggacatgatggcagcatatttatatgggatattacaaaa
ggtaccaagatgaaacattattttaatatgattgaaggacaaggacatggagctgtgttt
gactgtaagttttcacaggatggacagcattttgcctgtacagattctcatgggcacctt
ctgatatttggttttggatgcagcaaaccatatgaaaagattcctgatcagatgttcttc
catactgactatcgaccacttattagagattctaataattatgtcttagatgagcaaact
cagcaggctcctcatcttatgcctccaccattcttggtagatgtagatggaaatcctcat
ccaaccaagtatcagagattagtaccaggccgagaaaattctgcagatgaacatttgatt
ccacagctgggctatgtggcaacaagtgatggagaggtgattgaacaaattataagcctg
caaaccaatgataatgatgaacgcagcccagaatcgagtattcttgatggaatgataaga
cagttgcagcagcagcaagatcagagaatgggagcagatcaggatactattccaagagga
ctttcaaatggtgaagaaacaccccggagaggttttagaaggctgagcttagacattcag
tcccctccaaatattggtctgcgtcgtagtggacaagttgaaggtgttcgtcagatgcat
caaaacgctccacgcagtcagattgctacagaacgtgacctgcaggcttggaaacgaaga
gtggttgtaccagaggtaccactaggcatatttaggaagctggaagacttccgattagag
aaaggtgaagaggaaagaaatctttatataataggaagaaaaagaaagactcttcagctc
tcacataagtcggattcagtggttttggtatcacagtctagacaaaggacatgtaggcgt
aaatatccaaattatggtagaagaaatcgtagctggcgtgagttatcttctggaaatgag
tcttcaagctctgtaagacatgagacttcctgtgatcagagtgaaggttctggttcttca
gaagaggatgaatggagaagtgacagaaaaagtgagagttacagcgaaagttcaagtgac
tcttcatctagatattccgattggacagctgatgcgggcatcaatttgcagcctccttta
agaacatcatgtcgtcgacgaattactcgattttgtagtagttcagaagatgaaatatct
actgagaatttatctcctccaaaaagaagacgaaagagaaagaaagaaaataagcctaag
aaggagaatttgcggaggatgactccagcagagcttgcaaatatggagcatttatatgaa
tttcaccctccagtttggattactgacaccacacttagaaaatctccttttgttcctcaa
atgggtgatgaggtaatatattttcgacagggtcatgaagcttatattgaggctgtaaga
agaaataatatttatgaactgaaccctaataaggagccatggagaaaaatggatcttagg
gatcaagaattggttaaaatagttggaatacgatatgaagttgggccccctacactctgt
tgcctaaaactagcatttatagatccagcaactggaaaacttatggacaaatctttctct
attagatatcatgatatgccagatgttattgactttcttgtattgcgtcaattttatgat
gaagcaagacagaggaattggcagtcttgtgacagattccgctctattattgatgatgct
tggtggtttggaacagtgttaagtcaagagccatatcaaccacagtatcctgatagtcat
ttccagtgttatattgttaggtgggataatactgaaattgaaaaacttagcccatgggac
atggaaccaattcctgataatgttgatccacctgaagaattaggagctagtatttctgtc
acaacagatgagctagagaaattgctctataaaccacaagctggtgaatggggtcagaaa
tcaagagatgaagaatgtgatagaattatcagtggtatagatcaacttttgaatcttgat
atagcagcagcttttgcaggccctgttgatttgtgtacatacccgaagtactgtactgta
gtagcttatccaaccgatctttacacaattcgaatgagacttgttaatcgattttacagg
aggctgtctgcgttagtttgggaagtcagatatatagaacataatgccagaacatttaac
gaacctgagagtgtaattgcaagatcagctaaaaagataactgaccaacttttaaaattt
atcaagaatcaacactgtacaaatatctcagaactttctaacacatctgaaaatgatgag
caaaatgctgaggatttggatgatagtgatcttcctaaaacatcttctggaaggaggaga
gtccatgatgggaaaaaaagcatcagagctacgaactatgttgaaagcaactggaagaaa
cagtgtaaggaactagtgaacttaatttttcagtgtgaagattctgaaccatttagacaa
cctgttgatttggttgaatatccagactacagagatattatagataccccaatggatttt
ggaacagtaagggaaactctagatgcgggaaattatgacagccctttggagttttgcaaa
gacatccggctgatatttagcaatgcaaaagcgtatacaccaaacaaaagatcaaagatt
tatagtatgaccttgagattatctgccttatttgaagaaaaaatgaagaaaatctcttct
gattttaaaattggtcaaaaattcaatgaaaaacttcgaagaagccagaggttcaagcaa
cggcaaaattgtaaaggtgacagtcagcctaacaaaagtatcagaaacctcaagccgaag
aggttaaaatctcagacaaaaataattcctgagttggtaggttctcctacccagtctacc
tcaagtaggacagcttatcttggaacccacaagacaagtgctggtatctcttcaggtgtt
acttctggtgactcttcagattcagcagaatcatcagaaaggaggaaaagaaatagacct
ataacaaatggttctacattatctgaaagtgaagtggaagattctttagctacctctttg
tcatcgtcagcttccagtagttctgaggaaagcaaagagagttccagagctcgtgaatcc
tcctcacgcagtgggctatccagaagcagcaatctcagggtaaccagaactagagctgct
caaagaaaaactggtcccgtttcattagcaaatggatgtggcagaaaagccactcgaaag
agagtctatttaagtgattctgataacaattcattggagactggtgaaattctaaaagcc
agagctggaaataaccgaaaagtcttaaggaagtgtgctgctgtggctgccaataaaata
aagctaatgagtgatgtagaagagaattctagctctgaaagtgtctgttctggtcggaag
ctgcctcaccgcaatgcttctgctgtagctagaaaaaagttattacataattctgaagat
gaacagagcttaaagtcagaaattgaagaagaggagctaaaagatgaaaatcaactatta
ccagtgtccagttctcacactgcccagagcaatgttgatgaatctgaaaacagagactca
gagtcagaaagtgatttgcgggtagcccggaaaaattggcatgctaatggttacaagtcc
catactccagcaccttcaaagacaaaatttcttaaaatagagtcttctgaggaagactct
aaaagtcatgattcagatcatgcatgtaacagaactgctggcccatcaacgtctgtgcag
aaacttaaggcagagagcatctcagaggaagcagattctgaaccaggaagatctggtggt
aggaaatacaatacatttcacaagaatgcgagtttctttaaaaaaaccaagattctgagt
gactcagaagactctgaatctgaagagcaagatagagaagatgggaaatgtcataaaatg
gaaatgaacccaatttcaggaaatctgaactgtgaccctattgctatgtcccagtgttcc
tcagatcatggatgtgaaactgatttagattcagatgatgacaaaatagaaaaaccaaac
aattttatgaaagattctgcatcacaagacaatggactaagcagaaaaatttccaggaaa
agggtctgttccagtgactcagacagtagtttacaggtggttaagaaatcatcaaaagcc
agaacaggtctcctgaggattactcgaagatgtgcagctacggctgccaataagatcaag
ctcatgagtgatgtagaagatgtcagtttagaaaatgtgcacactagaagcaaaaatgga
aggaaaaaacctctccatcttgcttgtactacagctaagaagaaattgagtgattgtgaa
ggaagtgtacattgtgaagtaccaagtgaacagtatgcctgtgaaggcaagccacctgat
cctgactccgaaggtagtacaaaagtgcttagtcaggctctaaatggagactcagactct
gaagatatgttgaattcagaacacaagcacaggcataccaatattcacaaaatagatgca
ccttctaaaagaaaaagttcctctgttacatcttcaggagaagattcaaaaagtcatatt
ccagggagtgagactgataggacattttcttcagagtcaaccttggcacaaaaagctact
gcagagaataattttgaagtggaactgaattatgggctgcgcaggtggaatggcagaaga
ctcaggacctatggaaaggctccttttagtaagacaaaagtgattcatgattcacaggaa
acagcagagaaggaagtaaaaaggaagagatcgcatcctgaattggaaaatgtgaaaatc
tctgaaacaactgggaattcaaagtttagacctgatactagttccaaatcatcagatttg
ggatctgtaactgaatcagatattgactgtactgataatacaaaaaccaaaaggaggaaa
acgaaaggaaaagcaaaagtagttagaaaagaatttgttcctagagacagagaacccaat
acaaaagtgagaacatgtatgcataatcagaaggatgcagtgcagatgcctagtgaaact
ctgaaagcaaaaatggtacctgagaaagttccccgcagatgtgctactgttgctgcaaat
aaaataaagataatgagtaatctaaaagaaacgatctcaggaccagaaaatgtctggatt
aggaagagtagcagaaaactgccccatcgaaatgcttctgctgcggctaagaaaaaatta
ctgaatgtttataaagaggatgatacaaccataaattctgaaagtgaaaaagagctagaa
gatattaatagaaaaatgctttttttaagggggttcagatcctggaaagaaaatgcacaa
tag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG ORTHOLOGY (1)   
   RefGene (27)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (88)   
   RefSeq(nuc) (14)   
   GenBank (37)   
   EMBL (37)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (153)   

Download RDF
DBGET integrated database retrieval system