KEGG   Homo sapiens (human): 54490
Entry
54490             CDS       T01001                                 
Symbol
UGT2B28
Name
(RefSeq) UDP glucuronosyltransferase family 2 member B28
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00040  Pentose and glucuronate interconversions
hsa00053  Ascorbate and aldarate metabolism
hsa00140  Steroid hormone biosynthesis
hsa00830  Retinol metabolism
hsa00860  Porphyrin metabolism
hsa00980  Metabolism of xenobiotics by cytochrome P450
hsa00982  Drug metabolism - cytochrome P450
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa01240  Biosynthesis of cofactors
hsa04976  Bile secretion
hsa05204  Chemical carcinogenesis - DNA adducts
hsa05207  Chemical carcinogenesis - receptor activation
Module
hsa_M00014  Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    54490 (UGT2B28)
   00053 Ascorbate and aldarate metabolism
    54490 (UGT2B28)
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    54490 (UGT2B28)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    54490 (UGT2B28)
   00860 Porphyrin metabolism
    54490 (UGT2B28)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    54490 (UGT2B28)
   00982 Drug metabolism - cytochrome P450
    54490 (UGT2B28)
   00983 Drug metabolism - other enzymes
    54490 (UGT2B28)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    54490 (UGT2B28)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    54490 (UGT2B28)
   05207 Chemical carcinogenesis - receptor activation
    54490 (UGT2B28)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    54490 (UGT2B28)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     54490 (UGT2B28)
Glycosyltransferases [BR:hsa01003]
 Others
  Hydrophobic molecule
   54490 (UGT2B28)
SSDB
Motif
Pfam: UDPGT EryCIII-like_C Glyco_transf_4 Glyco_tran_28_C
Other DBs
NCBI-GeneID: 54490
NCBI-ProteinID: NP_444267
OMIM: 606497
HGNC: 13479
Ensembl: ENSG00000135226
UniProt: Q9BY64
Position
4:69280475..69295050
AA seq 529 aa
MALKWTSVLLLIHLGCYFSSGSCGKVLVWTGEYSHWMNMKTILKELVQRGHEVTVLASSA
SILFDPNDAFTLKLEVYPTSLTKTEFENIIMQQVKRWSDIQKDSFWLYFSQEQEILWEFH
DIFRNFCKDVVSNKKVMKKLQESRFDIIFADAFFPCGELLAALLNIPFVYSLCFTPGYTI
ERHSGGLIFPPSYIPVVMSKLSDQMTFMERVKNMIYVLYFDFWFQMCDMKKWDQFYSEVL
GRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNIDFVGGLHCKPAKPLPKEMEEFVQSSG
ENGVVVFSLGSVISNMTAERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQN
DLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTM
SSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHKGAKHLRVAA
RDLTWFQYHSLDVIGFLLACVATVIFVVTKFCLFCFWKFARKGKKGKRD
NT seq 1590 nt   +upstreamnt  +downstreamnt
atggctctgaagtggacttcagttcttctgctgatacatctcggttgttactttagctct
gggagttgtggaaaggtgctggtgtggaccggtgaatacagccattggatgaatatgaag
acaatcctgaaagagcttgttcagagaggtcatgaggtgactgtactggcatcttcagct
tccattctttttgatcccaatgacgcattcactcttaaactcgaagtttatcctacatct
ttaactaaaactgaatttgagaatatcatcatgcaacaggttaagagatggtcagacatt
caaaaagatagcttttggttatatttttcacaagaacaagaaatcctgtgggaatttcat
gacatatttagaaacttctgtaaagatgtagtttcaaataagaaagttatgaaaaaacta
caagagtcaagatttgacatcatttttgcagatgctttttttccttgtggtgagctgctg
gctgcgctacttaacataccgtttgtgtacagtctctgcttcactcctggctacacaatt
gaaaggcacagtggaggactgattttccctccttcctacatacctgttgttatgtcaaaa
ttaagtgatcaaatgactttcatggagagggtaaaaaacatgatctatgtgctttatttt
gacttttggttccaaatgtgtgatatgaagaagtgggatcagttttacagtgaagtttta
ggaagacccactaccttatttgagacaatggggaaagctgacatatggcttatgcgaaac
tcctggagttttcaatttcctcatccattcttaccaaacattgattttgttggaggactc
cactgcaaacctgccaaacccctacctaaggaaatggaggaatttgtacagagctctggt
gaaaatggtgttgtggtgttttctctggggtcagtgataagtaacatgacagcagaaagg
gccaacgtaattgcaacagcccttgccaagatcccacaaaaggttctgtggagatttgat
gggaataaaccagatgccttaggtctcaatactcggctgtataagtggataccccagaat
gaccttctaggtcttccaaaaaccagagcttttataactcatggtggagccaatggcatc
tatgaggcaatctaccatgggatccctatggtaggcattccattgttttgggatcaacct
gataacattgctcacatgaaggccaagggagcagctgttagactggacttccacacaatg
tcgagtacagacctgctgaatgcactgaagacagtaattaatgatccttcatataaagag
aatgttatgaaattatcaataattcaacatgatcaaccagtaaagcccctgcatcgagca
gtcttctggattgaatttgtgatgtgccacaaaggagccaaacaccttcgagttgcagcc
cgtgacctcacctggttccagtaccactctttggatgtgattgggtttctgctggcctgt
gtggcaactgtgatatttgtcgtcacaaagttttgtctgttttgtttctggaagtttgct
agaaaagggaagaagggaaaaagagattag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (15)   
   KEGG PATHWAY (13)   
   KEGG MODULE (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (40)   
   KEGG COMPOUND (40)   
Chemical reaction (21)   
   KEGG ENZYME (1)   
   KEGG REACTION (20)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
Protein domain (4)   
   Pfam (4)   
All databases (118)   

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