KEGG   Homo sapiens (human): 54936
Entry
54936             CDS       T01001                                 
Symbol
ADPRS, ADPRHL2, ARH3, CONDSIAS
Name
(RefSeq) ADP-ribosylserine hydrolase
  KO
K11687  poly(ADP-ribose) glycohydrolase ARH3 [EC:3.2.1.143]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03410  Base excision repair
Network
nt06504  Base excision repair
  Element
N01434  Base excision and strand cleavage by bifunctional glycosylase
Disease
H02572  Neurodegeneration, childhood-onset, stress-induced, with variable ataxia and seizures
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    54936 (ADPRS)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.143  poly(ADP-ribose) glycohydrolase
     54936 (ADPRS)
SSDB
Motif
Pfam: ADP_ribosyl_GH FUSC_2
Other DBs
NCBI-GeneID: 54936
NCBI-ProteinID: NP_060295
OMIM: 610624
HGNC: 21304
Ensembl: ENSG00000116863
UniProt: Q9NX46
Structure
Position
1:36088892..36093932
AA seq 363 aa
MAAAAMAAAAGGGAGAARSLSRFRGCLAGALLGDCVGSFYEAHDTVDLTSVLRHVQSLEP
DPGTPGSERTEALYYTDDTAMARALVQSLLAKEAFDEVDMAHRFAQEYKKDPDRGYGAGV
VTVFKKLLNPKCRDVFEPARAQFNGKGSYGNGGAMRVAGISLAYSSVQDVQKFARLSAQL
THASSLGYNGAILQALAVHLALQGESSSEHFLKQLLGHMEDLEGDAQSVLDARELGMEER
PYSSRLKKIGELLDQASVTREEVVSELGNGIAAFESVPTAIYCFLRCMEPDPEIPSAFNS
LQRTLIYSISLGGDTDTIATMAGAIAGAYYGMDQVPESWQQSCEGYEETDILAQSLHRVF
QKS
NT seq 1092 nt   +upstreamnt  +downstreamnt
atggccgcagcggcgatggcggcagcggcaggtggaggggctggcgcggcccgctccctc
tcgcgcttccgaggctgcctggctggcgcgctgctcggggactgcgtgggctccttctac
gaggcccacgacaccgtcgacctgacgtcagtcctgcgtcatgtccagagtctggagccg
gaccccggcacgcccgggagtgagcggacagaagccttgtactacacagatgacacagcc
atggccagggccctggtgcagtccctgctagccaaggaggcctttgacgaggtggacatg
gctcacagatttgctcaggagtacaagaaagaccctgacaggggctatggtgctggagta
gtcactgtcttcaagaagctcctgaaccccaaatgtcgcgatgtctttgagcctgcccgg
gcccagtttaacgggaaaggctcctatggcaatggaggtgccatgcgggtggctggcatc
tccctggcctatagcagtgtccaggatgtgcagaagtttgcccggctctcggcccagctg
acacacgcctcctccctgggttacaatggcgccatcctgcaggccctggctgtgcacctg
gccttgcagggcgagtcttccagcgagcactttctcaagcaactcctgggccacatggag
gatctggagggtgatgcccagtccgtcttggatgccagggagttgggcatggaggagcgt
ccatactccagccgcctgaagaagattggagagcttctagaccaggcatcggtgaccagg
gaggaagtggtgtctgagctagggaatggcattgctgcctttgagtcggtacccaccgcc
atctactgcttcctacgctgcatggagccagaccctgagatcccttctgccttcaatagc
ctccaaaggactctcatttattccatctcacttggtggggacacagacaccattgccacc
atggctggggccattgctggtgcctactatgggatggatcaggtgccagagagctggcag
caaagctgtgaaggctacgaggagacagacatcctggcccaaagcctgcaccgtgtcttc
cagaagagttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (21)   
   RefSeq(nuc) (3)   
   GenBank (9)   
   EMBL (9)   
3D Structure (12)   
   PDB (12)   
Protein domain (2)   
   Pfam (2)   
All databases (58)   

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