KEGG   Homo sapiens (human): 55737
Entry
55737             CDS       T01001                                 
Symbol
VPS35, MEM3, PARK17
Name
(RefSeq) VPS35 retromer complex component
  KO
K18468  vacuolar protein sorting-associated protein 35
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
Disease
H00057  Parkinson disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    55737 (VPS35)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    55737 (VPS35)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Rab GTPases and associated proteins
   Retromer subcomplex
    55737 (VPS35)
SSDB
Motif
Pfam: Vps35 CENP-O FerA Imm5
Other DBs
NCBI-GeneID: 55737
NCBI-ProteinID: NP_060676
OMIM: 601501
HGNC: 13487
Ensembl: ENSG00000069329
UniProt: Q96QK1
Structure
Position
16:complement(46656132..46689178)
AA seq 796 aa
MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSP
KSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVK
SFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSM
DFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQ
IVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIII
ALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMK
CYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKH
FHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPD
PEDFADEQSLVGRFIHLLRSEDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAYQLA
FRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHE
TVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKL
LKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLF
IEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLR
RESPESEGPIYEGLIL
NT seq 2391 nt   +upstreamnt  +downstreamnt
atgcctacaacacagcagtcccctcaggatgagcaggaaaagctcttggatgaagccata
caggctgtgaaggtccagtcattccaaatgaagagatgcctggacaaaaacaagcttatg
gatgctctaaaacatgcttctaatatgcttggtgaactccggacttctatgttatcacca
aagagttactatgaactttatatggccatttctgatgaactgcactacttggaggtctac
ctgacagatgagtttgctaaaggaaggaaagtggcagatctctacgaacttgtacagtat
gctggaaacattatcccaaggctttaccttttgatcacagttggagttgtatatgtcaag
tcatttcctcagtccaggaaggatattttgaaagatttggtagaaatgtgccgtggtgtg
caacatcccttgaggggtctgtttcttcgaaattaccttcttcagtgtaccagaaatatc
ttacctgatgaaggagagccaacagatgaagaaacaactggtgacatcagtgattccatg
gattttgtactgctcaactttgcagaaatgaacaagctctgggtgcgaatgcagcatcag
ggacatagccgagatagagaaaaaagagaacgagaaagacaagaactgagaattttagtg
ggaacaaatttggtgcgcctcagtcagttggaaggtgtaaatgtggaacgttacaaacag
attgttttgactggcatattggagcaagttgtaaactgtagggatgctttggctcaagaa
tatctcatggagtgtattattcaggttttccctgatgaatttcacctccagactttgaat
ccttttcttcgggcctgtgctgagttacaccagaatgtaaatgtgaagaacataatcatt
gctttaattgatagattagctttatttgctcaccgtgaagatggacctggaatcccagcg
gatattaaactttttgatatattttcacagcaggtggctacagtgatacagtctagacaa
gacatgccttcagaggatgttgtatctttacaagtctctctgattaatcttgccatgaaa
tgttaccctgatcgtgtggactatgttgataaagttctagaaacaacagtggagatattc
aataagctcaaccttgaacatattgctaccagtagtgcagtttcaaaggaactcaccaga
cttttgaaaataccagttgacacttacaacaatattttaacagtcttgaaattaaaacat
tttcacccactctttgagtactttgactacgagtccagaaagagcatgagttgttatgtg
cttagtaatgttctggattataacacagaaattgtctctcaagaccaggtggattccata
atgaatttggtatccacgttgattcaagatcagccagatcaacctgtagaagaccctgat
ccagaagattttgctgatgagcagagccttgtgggccgcttcattcatctgctgcgctct
gaggaccctgaccagcagtacttgattttgaacacagcacgaaaacattttggagctggt
ggaaatcagcggattcgcttcacactgccacctttggtatttgcagcttaccagctggct
tttcgatataaagagaattctaaagtggatgacaaatgggaaaagaaatgccagaagatt
ttttcatttgcccaccagactatcagtgctttgatcaaagcagagctggcagaattgccc
ttaagactttttcttcaaggagcactagctgctggggaaattggttttgaaaatcatgag
acagtcgcatatgaattcatgtcccaggcattttctctgtatgaagatgaaatcagcgat
tccaaagcacagctagctgccatcaccttgatcattggcacttttgaaaggatgaagtgc
ttcagtgaagagaatcacgaacctctgaggactcagtgtgcccttgctgcatccaaactt
ctaaagaaacctgatcagggccgagctgtgagcacctgtgcacatctcttctggtctggc
agaaacacggacaaaaatggggaggagcttcacggaggcaagagggtaatggagtgccta
aaaaaagctctaaaaatagcaaatcagtgcatggacccctctctacaagtgcagcttttt
atagaaattctgaacagatatatctatttttatgaaaaggaaaatgatgcggtaacaatt
caggttttaaaccagcttatccaaaagattcgagaagacctcccgaatcttgaatccagt
gaagaaacagagcagattaacaaacattttcataacacactggagcatttgcgcttgcgg
cgggaatcaccagaatccgaggggccaatttatgaaggtctcatcctttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (49)   
   RefSeq(nuc) (5)   
   GenBank (22)   
   EMBL (22)   
3D Structure (10)   
   PDB (10)   
Protein domain (4)   
   Pfam (4)   
All databases (114)   

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