KEGG   Homo sapiens (human): 57053
Entry
57053             CDS       T01001                                 
Symbol
CHRNA10
Name
(RefSeq) cholinergic receptor nicotinic alpha 10 subunit
  KO
K04811  nicotinic acetylcholine receptor alpha-10
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Acetylcholine (DG01133): D00999<JP/US>
Atracurium (DG00771): D00758<US>
Cisatracurium: D00759<US>
Cytisinicline: D07770
Dimethyltubocurarine: D07272
Doxacurium chloride: D00760
Fazadinium bromide: D07273
Hexamethonium bromide: D02204
Lobeline (DG01287): D02202 D02364 D08138
Mecamylamine (DG00252): D00611<US>
Mivacurium chloride: D00763
Nicotine (DG00994): D03365<JP/US> D05156 D05157
Pancuronium (DG00769): D00492
Pipecuronium bromide: D00764
Rocuronium bromide: D00765<JP/US>
Trimetaphan (DG00251): D00612
Tubocurarine (DG00767): D02207 D08655
Vecuronium (DG00770): D00767<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    57053 (CHRNA10)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    57053 (CHRNA10)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  Acetylcholine (nicotinic)
   57053 (CHRNA10)
SSDB
Motif
Pfam: Neur_chan_LBD Neur_chan_memb MASE10
Other DBs
NCBI-GeneID: 57053
NCBI-ProteinID: NP_065135
OMIM: 606372
HGNC: 13800
Ensembl: ENSG00000129749
UniProt: Q9GZZ6
Position
11:complement(3665587..3671384)
AA seq 450 aa
MGLRSHHLSLGLLLLFLLPAECLGAEGRLALKLFRDLFANYTSALRPVADTDQTLNVTLE
VTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYN
KADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGH
QLDVRPRGAAASLADFVENVEWRVLGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYV
CNLLLPCVLISLLAPLAFHLPADSGEKVSLGVTVLLALTVFQLLLAESMPPAESVPLIGK
YYMATMTMVTFSTALTILIMNLHYCGPSVRPVPAWARALLLGHLARGLCVRERGEPCGQS
RPPELSPSPQSPEGGAGPPAGPCHEPRCLCRQEALLHHVATIANTFRSHRAAQRCHEDWK
RLARVMDRFFLAIFFSMALVMSLLVLVQAL
NT seq 1353 nt   +upstreamnt  +downstreamnt
atggggctccggagccaccacctcagcctgggccttctgcttctgtttctactccctgca
gagtgcctgggagctgagggccggctggctctcaagctgttccgtgacctctttgccaac
tacacaagtgccctgagacctgtggcagacacagaccagactctgaatgtgaccctggag
gtgacactgtcccagatcatcgacatggatgaacggaaccaggtgctgaccctgtatctg
tggatacggcaggagtggacagatgcctacctacgatgggaccccaatgcctatggtggc
ctggatgccatccgcatccccagcagtcttgtgtggcggccagacatcgtactctataac
aaagccgacgcgcagcctccaggttccgccagcaccaacgtggtcctgcgccacgatggc
gccgtgcgctgggacgcgccggccatcacgcgcagctcgtgccgcgtggatgtagcagcc
ttcccgttcgacgcccagcactgcggcctgacgttcggctcctggactcacggcgggcac
caactggatgtgcggccgcgcggcgctgcagccagcctggcggacttcgtggagaacgtg
gagtggcgcgtgctgggcatgccggcgcggcggcgcgtgctcacctacggctgctgctcc
gagccctaccccgacgtcaccttcacgctgctgctgcgccgccgcgccgccgcctacgtg
tgcaacctgctgctgccctgcgtgctcatctcgctgcttgcgccgctcgccttccacctg
cctgccgactcaggcgagaaggtgtcgctgggcgtcaccgtgctgctggcgctcaccgtc
ttccagttgctgctggccgagagcatgccaccggccgagagcgtgccgctcatcgggaag
tactacatggccactatgaccatggtcacattctcaacagcactcaccatccttatcatg
aacctgcattactgtggtcccagtgtccgcccagtgccagcctgggctagggccctcctg
ctgggacacctggcacggggcctgtgcgtgcgggaaagaggggagccctgtgggcagtcc
aggccacctgagttatctcctagcccccagtcgcctgaaggaggggctggccccccagcg
ggcccttgccacgagccacgatgtctgtgccgccaggaagccctactgcaccacgtagcc
accattgccaataccttccgcagccaccgagctgcccagcgctgccatgaggactggaag
cgcctggcccgtgtgatggaccgcttcttcctggccatcttcttctccatggccctggtc
atgagcctcctggtgctggtgcaggccctgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (23)   
   KEGG DRUG (23)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (13)   
   RefSeq(nuc) (3)   
   GenBank (5)   
   EMBL (5)   
Protein domain (3)   
   Pfam (3)   
All databases (59)   

Download RDF
DBGET integrated database retrieval system