KEGG   Homo sapiens (human): 57697
Entry
57697             CDS       T01001                                 
Symbol
FANCM, FAAP250, KIAA1596, POF15, SPGF28
Name
(RefSeq) FA complementation group M
  KO
K10896  fanconi anemia group M protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa03460  Fanconi anemia pathway
Network
nt06508  Interstrand crosslink repair
  Element
N01464  Fanconi anemia pathway
Disease
H00238  Fanconi anemia
H00627  Premature ovarian failure
H01282  Spermatogenic failure
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03460 Fanconi anemia pathway
    57697 (FANCM)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    57697 (FANCM)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   FA (Fanconi anemia) pathway
    FA core complex
     57697 (FANCM)
SSDB
Motif
Pfam: FANCM-MHF_bd DEAD Helicase_C ResIII ERCC4 HHH_2
Other DBs
NCBI-GeneID: 57697
NCBI-ProteinID: NP_065988
OMIM: 609644
HGNC: 23168
Ensembl: ENSG00000187790
UniProt: Q8IYD8
Structure
Position
14:45135930..45200890
AA seq 2048 aa
MSGRQRTLFQTWGSSISRSSGTPGCSSGTERPQSPGSSKAPLPAAAEAQLESDDDVLLVA
AYEAERQLCLENGGFCTSAGALWIYPTNCPVRDYQLHISRAALFCNTLVCLPTGLGKTFI
AAVVMYNFYRWFPSGKVVFMAPTKPLVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEI
WCSKRVLFLTPQVMVNDLSRGACPAAEIKCLVIDEAHKALGNYAYCQVVRELVKYTNHFR
ILALSATPGSDIKAVQQVITNLLIGQIELRSEDSPDILTYSHERKVEKLIVPLGEELAAI
QKTYIQILESFARSLIQRNVLMRRDIPNLTKYQIILARDQFRKNPSPNIVGIQQGIIEGE
FAICISLYHGYELLQQMGMRSLYFFLCGIMDGTKGMTRSKNELGRNEDFMKLYNHLECMF
ARTRSTSANGISAIQQGDKNKKFVYSHPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVM
IFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTL
VSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGREERIYNQ
SQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKS
SIFSYRDGMRQSSLKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKP
AQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRHEEGECSYELE
VESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIV
KQTHIKPTKIVSLKKKVSKEIKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRT
SDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFNDEKSVSSNLF
LPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENL
LFLPCAEHLRSDKCTCLLSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSL
CDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQDESLLLFEDV
NTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANS
FKSRDQRGVQEEKVKNHEDIFDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLY
GRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEEL
LSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNST
FDYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPED
QKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGNARRGIKVPKR
QSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSE
MRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSE
EEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNV
NDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKD
TISEVSDFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRP
HLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNR
MVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDS
LLTTLIGAGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIP
NISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVFDIQMLPNDLN
QDRLKSDI
NT seq 6147 nt   +upstreamnt  +downstreamnt
atgagcggacggcaaagaacgctttttcagacgtggggctcaagtatctcccgatcatct
gggactccgggttgcagctccggaactgagcgacctcagagccctggcagctccaaggcg
cctttgccagcagcagcggaggctcagctggagtcggacgatgatgtgttgcttgtcgcg
gcgtacgaggctgagcggcagttgtgtctagagaatggcgggttctgcacctccgcgggc
gccctgtggatttaccctaccaattgcccagtgcgggactaccagctgcacatttcccgg
gctgctctgttttgcaatacgctggtgtgtctgcctaccggactgggaaagacctttatt
gccgccgtggtcatgtacaatttctaccgctggttcccttcaggaaaggtggtcttcatg
gccccaacgaaacccttggtgacacagcagatcgaggcttgctaccaggtgatgggtatc
ccgcaatcccacatggccgaaatgacagggtctacacaagcttccaccaggaaggaaata
tggtgcagtaagagagtgctttttcttacacctcaggtcatggtaaatgacctttctaga
ggagcttgtcccgctgctgaaataaagtgtttagttattgatgaagctcataaagctctc
ggaaactatgcttattgccaggttgtaagagaactagtcaaatatacaaatcactttaga
atcttggctctaagtgccacaccaggtagtgatataaaggctgtgcaacaagttattact
aacctgctaattgggcagatagagcttcgttctgaagattctccagatattttgacatat
tctcatgaaagaaaagttgaaaagcttattgttccgcttggtgaagaacttgcagccatc
caaaagacctatatccagattttggaatcatttgctcgttctttgattcagaggaatgtt
ttgatgagaagggatatcccaaatctaacaaaatatcagataattctggcaagagatcag
tttaggaaaaacccatctccgaatattgtgggaatacaacaaggcataatcgagggagag
tttgctatttgtattagtttatatcatggttatgaattattgcagcaaatgggaatgaga
tcattatatttcttcctttgtggaattatggatggaactaaagggatgacacggtcaaaa
aatgaacttggccgaaatgaagacttcatgaaactctataatcatctagagtgtatgttt
gcacgtacacgtagtacttcagcaaatggtatttctgctatccaacaaggagataaaaat
aaaaaatttgtttatagtcatccaaagttaaagaaattagaagaagttgtaattgaacac
ttcaagtcatggaatgctgaaaacactactgaaaagaaacgtgatgagacccgagttatg
atcttctcttcatttcgagatagtgttcaagaaattgcagaaatgctttcacagcatcag
ccaattattagagtaatgacttttgtcggccatgcctcagggaaaagcacgaagggtttt
acccagaaggagcaactggaggtagtgaaacagtttcgtgacggtggttacaacacgctg
gtttctacctgtgtgggtgaagaaggtttggatataggagaagttgatcttataatatgt
tttgattcccagaagagcccaattcgtcttgtacaacgaatgggtagaactggccgtaaa
cgtcaaggcaggatagttattatcctttctgaaggacgagaggaacgtatttataatcag
agtcagtccaacaaaagaagtatatataaagctatttcaagtaacaggcaggtccttcat
ttttaccaaagaagtccacgaatggttcctgatggaatcaacccaaaattacacaaaatg
ttcatcacacatggtgtctatgaaccagagaagccttctcggaacttgcagcgaaagtca
tctatcttttcctatagggatggaatgaggcaaagtagcctaaagaaagattggttctta
tcagaagaagaatttaaattatggaacagactttatagattaagggacagtgatgaaatt
aaagagataacattgcctcaagttcagttttcttctttacaaaatgaggaaaacaaacca
gctcaagaatcaaccactggaattcatcaactctctctctctgaatggagactgtggcaa
gatcatcctttgcctacacatcaagttgatcactcagatcgatgccgccattttataggc
cttatgcaaatgatagagggaatgagacacgaagagggagaatgcagctatgaattggaa
gttgaatcttatttacaaatggaagatgttacctcaacatttattgctcccaggaatgaa
tctaataatcttgccagtgacacctttatcactcacaagaaatcgtcatttataaagaac
ataaatcaaggcagttcatcctcagtgatagaatctgatgaagaatgtgctgaaattgtt
aaacaaactcatatcaaacctactaaaattgtttctttaaagaaaaaagtgtctaaagaa
ataaaaaaagatcagcttaaaaaagaaaataatcacggtattatagattctgtagataat
gacagaaattccactgttgaaaatatttttcaagaagacctaccaaatgataaaaggaca
tcagatacagatgaaattgctgccacatgtactattaatgaaaatgttattaaagaaccg
tgtgtgttattaacagagtgtcagtttacaaataaatccactagttcacttgctggaaat
gttttagattctggttataacagtttcaatgatgaaaaatctgtttcatctaacttattt
cttccattcgaagaagagctttatattgttagaacagatgaccaattttataattgtcac
tcattgacaaaagaggtactagctaatgtagagagatttttatcttattctcctccgcct
ctcagtggactctcagacttggaatatgaaattgctaagggtactgcacttgagaatttg
cttttcttaccctgtgcagagcatttacgaagtgataaatgcacctgtttgctgtcacat
tcagctgtgaattctcaacagaatttagaattgaattcacttaaatgtataaattatcca
tctgaaaaaagttgcctttatgatatacctaatgataatatttctgatgagccaagtctc
tgtgactgtgatgtacataaacataatcaaaatgaaaatttagtacctaacaatcgtgtt
caaatacacagaagccctgcacagaatttagttggagagaacaatcatgatgttgataac
agtgacctcccagtattgtccactgatcaagatgaaagtttgctgttatttgaagatgtt
aatacagagttcgacgatgtgagtctttcacccttgaacagtaaaagcgaatctttacct
gtgtcagacaaaactgctattagtgaaacgcctctggtctctcagttcttaatttctgat
gaacttttgttggacaataattctgaactccaagatcaaatcacccgtgatgctaatagt
tttaaatctcgtgatcagagaggtgtacaggaagaaaaagtgaagaatcatgaggatatt
tttgattgctctagggatttattttctgttacctttgatttaggattctgtagtccagat
tctgatgatgaaatattggaacatacatcagatagcaatagacctctagatgatctatat
ggaaggtatttggaaattaaggagataagtgatgcaaattatgtttcgaatcaagcacta
ataccaagagatcatagtaaaaattttactagtggaactgttattatcccatcaaatgaa
gatatgcagaatccaaattatgtacatttgccactgagtgcagcaaaaaatgaagaattg
ttatctcctggttattctcagttttctttaccagtgcaaaaaaaagttatgagtacacca
ctctctaaatcaaacacattgaactcattttctaagataagaaaggaaatacttaagaca
ccagattctagtaaggaaaaagtaaacctacaaagattcaaagaagcattgaattcaact
tttgattattcagaattttctctagaaaagtctaaaagcagtggtccaatgtatctgcat
aaatcctgtcattctgttgaagatggacaattattaacaagtaacgaaagtgaagatgac
gagattttccgaagaaaagttaaaagagcaaaaggaaatgttttaaactctcctgaggat
cagaaaaatagtgaagttgattctccacttcatgctgtcaaaaagcgcagatttcctata
aacagatcagaattatcatctagtgatgagagtgagaattttcccaaaccatgttcacaa
ttagaagacttcaaggtttgtaacgggaatgccagaagaggcatcaaagtcccaaagaga
cagagtcacttaaagcatgtagctaggaagtttttagatgatgaagcagaactttctgaa
gaagatgcagaatatgtttcatcagatgaaaatgatgagtcagaaaatgaacaagattcc
tcattacttgactttttaaatgatgaaactcaactttcacaggctataaatgattctgaa
atgagagctatttacatgaaatctttgcgtagtccaatgatgaacaataagtacaaaatg
attcataagacacataaaaacataaacattttctcgcagattcctgaacaagatgaaacc
tatttagaggatagtttttgtgttgatgaagaggagtcttgcaaaggccaatcaagtgaa
gaagaagtttgtgttgattttaacttaataactgatgattgctttgcaaatagtaaaaag
tataaaactcgacgtgcagtaatgctaaaagaaatgatggaacaaaattgtgcacattca
aaaaagaaattatccagaattattttaccagatgattcaagtgaggaggagaacaatgta
aatgataaaagagaatctaatattgcggttaacccaagcactgttaagaagaacaaacaa
caggaccattgtttaaattcagtgccttctggatcttctgcgcagtccaaggtgcgttct
actccaagagttaatccattagcaaagcagagcaaacagacatcgctgaatttaaaggat
acaatttccgaagtctcagacttcaaacctcagaatcataatgaagtccagtctaccaca
ccacccttcactactgttgattcacagaaagactgtagaaaatttccagttccacagaag
gatggtagtgctttggaggattctagcacttcaggggcatcctgttccaagtcaagacca
catttagctgggacacatacttctcttagacttccgcaggaaggaaaaggaacctgtatt
cttgtaggtggtcatgaaatcacttctggattagaagtaatttcttccctaagagcaatt
catgggttgcaagtagaagtttgtcctcttaatggctgtgattacatcgtgagtaatcgc
atggtggtggaaaggaggtctcaatctgagatgttaaatagtgtcaataagaacaagttc
attgagcagatccagcacctgcagagtatgtttgaaagaatatgtgtgattgtggaaaag
gacagagaaaaaacaggagacacatcaaggatgtttaggagaacaaagagctatgacagc
ctgctgactaccttaattggcgctggaatccgaattcttttcagttcctgccaagaagaa
accgcagatttgctaaaggaactgtctttagtggaacaaagaaagaatgttggtattcat
gttccaacagtggtgaatagtaataaaagtgaggcactccagttttatttaagtattccc
aatataagttatataactgcattaaatatgtgtcaccagttttcatctgtgaaaaggatg
gctaacagctcacttcaagaaatctccatgtatgcacaagtaactcatcagaaggctgag
gagatctatagatatattcactatgtatttgacatacaaatgttaccaaatgatcttaac
caagatagactgaaatctgatatataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (6)   
   KEGG DISEASE (3)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (43)   
   KEGG ORTHOLOGY (1)   
   RefGene (36)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (21)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (19)   
DNA sequence (37)   
   RefSeq(nuc) (19)   
   GenBank (9)   
   EMBL (9)   
3D Structure (5)   
   PDB (5)   
Protein domain (6)   
   Pfam (6)   
All databases (124)   

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