KEGG   Homo sapiens (human): 57724
Entry
57724             CDS       T01001                                 
Symbol
EPG5, HEEW1, KIAA1632, VICIS
Name
(RefSeq) ectopic P-granules 5 autophagy tethering factor
  KO
K23883  ectopic P granules protein 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
Network
nt06532  Autophagy
  Element
N01721  Autophagosome and lysosome fusion, tethering factor
Disease
H02133  Vici syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    57724 (EPG5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    57724 (EPG5)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Other autophagy associated proteins
   Others
    57724 (EPG5)
SSDB
Motif
Pfam: DUF6077 Sda
Other DBs
NCBI-GeneID: 57724
NCBI-ProteinID: NP_066015
OMIM: 615068
HGNC: 29331
Ensembl: ENSG00000152223
UniProt: Q9HCE0 Q9BTI0
Structure
Position
18:complement(45800581..45967329)
AA seq 2579 aa
MAEAVKPQRRAKAKASRTKTKEKKKYETPQREESSEVSLPKTSREQEIPSLACEFKGDHL
KVVTDSQLQDDASGQNESEMFDVPLTSLTISNEESLTCNTEPPKEGGEARPCVGDSAVTP
KVHPGDNVGTKVETPKNFTEVEENMSVQGGLSESAPQSNFSYTQPAMENIQVRETQNSKE
DKQGLVCSSEVPQNVGLQSSCPAKHGFQTPRVKKLYPQLPAEIAGEAPALVAVKPLLRSE
RLYPELPSQLELVPFTKEQLKILEPGSWLENVESYLEEFDSMAHQDRHEFYELLLNYSRC
RKQLLLAEAELLTLTSDCQNAKSRLWQFKEEQMSVQGICADQVKVFSYHRYQRVEMNENA
LVELKKLFDAKSEHLHQTLALHSYTSVLSRLQVESYIYALLSSSAVLRSSAIHQQGRASK
QTESIPSDLCQLKECISVLFMFTRRVNEDTQFHDDILLWLQKLVSVLQRVGCPGDHLFLL
NHILRCPAGVSKWAVPFIQIKVLHNPSGVFHFMQSLALLMSPVKNRAEFMCHMKPSERKP
SSSGPGSGTWTLVDEGGEEDEDPETSWILLNEDDLVTILAQFPFHELFQHLLGFKAKGDY
LPETTRPQEMMKIFAFANSLVELLAVGLETFNRARYRQFVKRIGYMIRMTLGYVSDHWAQ
YVSHNQGSGLAQQPYSMEKLQVEFDELFLRAVLHVLKAKRLGIWLFMSEMPFGTLSVQML
WKLFYLMHQVESENLQQLSSSLQPAQCKQQLQDPEHFTNFEKCLSSMNSSEEICLLTTFA
QMAQARRTNVDEDFIKIIVLEIYEVSYVTLSTRETFSKVGRELLGTITAVHPEIISVLLD
RVQETIDQVGMVSLYLFKELPLYLWQPSASEIAVIRDWLLNYNLTVVKNKLACVILEGLN
WGFAKQATLHLDQAVHAEVALMVLEAYQKYLAQKPYAGILSESMKQVSYLASIVRYGETP
ETSFNQWAWNLILRLKLHKNDYGIQPNCPAVPFSVTVPDMTESPTFHPLLKAVKAGMPIG
CYLALSMTAVGHSIEKFCAEGIPLLGILVQSRHLRTVVHVLDKILPLFYPCQYYLLKNEQ
FLSHLLLFLHLDSGVPQGVTQQVTHKVAQHLTGASHGDNVKLLNSMIQAHISVSTQPNEV
GPVAVLEFWVQALISQHLWYREQPILFLMDHLCKAAFQLMQEDCIQKLLYQQHKNALGYH
CDRSLLSSLVSWIVAGNITPSFVEGLATPTQVWFAWTVLNMESIFEEDSQLRRVIEGELV
INSAFTPDQALKKAQTQLKLPIVPSLQRLLIYRWAHQALVTPSDHPLLPLIWQKFFLLYL
HRPGPQYGLPIDGCIGRRFFQSPAHINLLKEMKRRLTEVADFHHAASKALRVPAEGSEGL
PESHSGTPGYLTSPELHKELVRLFNVYILWLEDENFQKGDTYIPSLPKHYDIHRLAKVMQ
NQQDLWMEYLNMERIYHEFQETVGLWTQAKLESHSTPCSLSVQLDFTDPLLAKERVLSNL
RKHEAPQPPLALHPTKPPVPVISSAVLLSQKDATQLVCTDLNLLQQQARTAALRESQQVA
LDGELLDTMPKQYVNREEQTTLHLECRGSSGKKCQGAAVVTVQFEGMHKNEAISQQLHVL
RKEVKQLQAEAAKPPSLNIVEAAVHAENLITALVNAYKLQPTPGIQKVGISLFFTIVDYV
SDETQRHPPTRQFFTSCIEILGQVFISGIKSECRKVLETILKNSRLCSLLSPFFTPNAAP
AEFIQLYEQVVKFLSEDNSDMIFMLLTKFDLKQWLSATKPPLSDRTRLLESIHLALTAWG
LEPDEDILMPFNLFCKHWTYLLLYQFPDQYSDILRLLMQSSAEQLLSPECWKATLRALGC
CAPSCQQGAASTEGAVLPSSSDALLSDKQVMETIQWLSDFFYKLRLSKMDFKSFGLFSKW
SPYMADVKTFLGYLVKRLIDLEMTCLAQDPTASRKTVLKSLHSVIIQLFKPWILVLEDNE
SSQQRHYPWLESDTVVASSIVQLFTDCIDSLHESFKDKLLPGDAGALWLHLMHYCEACTA
PKMPEFILYAFHSTYRKLPWKDLHPDQMLMEAFFKVERGSPKSCFLFLGSVLCEVNWVSV
LSDAWNSSPHPETRSMIVCLLFMMILLAKEVQLVDQTDSPLLSLLGQTSSLSWHLVDIVS
YQSVLSYFSSHYPPSIILAKESYAELIMKLLKVSAGLSIPTDSQKHLDAVPKCQAFTHQM
VQFLSTLEQNGKITLAVLEQEMSKLLDDIIVFNPPDMDSQTRHMALSSLFMEVLMMMNNA
TIPTAEFLRGSIRTWIGQKMHGLVVLPLLTAACQSLASVRHMAETTEACITAYFKESPLN
QNSGWGPILVSLQVPELTMEEFLQECLTLGSYLTLYVYLLQCLNSEQTLRNEMKVLLILS
KWLEQVYPSSVEEEAKLFLWWHQVLQLSLIQTEQNDSVLTESVIRILLLVQSRQNLVAEE
RLSSGILGAIGFGRKSPLSNRFRVVARSMAAFLSVQVPMEDQIRLRPGSELHLTPKAQQA
LNALESMASSKQYVEYQDQILQATQFIRHPGHCLQDGKSFLALLVNCLYPEVHYLDHIR
NT seq 7740 nt   +upstreamnt  +downstreamnt
atggccgaggcggtgaagccccagcgccgggccaaggccaaggccagccggactaaaaca
aaggaaaagaagaagtatgaaactcctcagagggaagagtccagtgaagtctcccttcca
aaaacctccagagagcaggaaatcccttctctagcctgtgaattcaaaggagaccatctg
aaggtggtaactgattcccagctccaggatgatgccagtggacaaaatgagagtgaaatg
tttgatgtaccactcacctccttaactataagcaatgaagagtccctgacgtgtaacaca
gagcccccaaaggaagggggagaggccagaccctgtgtgggggacagtgcagtcactcca
aaggtccaccctggagacaatgttggaactaaagtagaaacccccaagaacttcacagag
gtagaggaaaatatgtcggtacaaggtggactttcagaaagtgcaccccaatctaatttt
tcttatactcagccagcaatggaaaatatacaagtcagagaaactcagaatagtaaagaa
gacaaacaaggcctggtttgttcttcagaggtgccacagaatgttggcttgcagagttct
tgcccagccaaacatggttttcagacacctagagtgaagaaactgtatccccagttgcca
gctgaaattgctggagaagcaccagctttggtggcagtgaaacccttgcttcgcagtgag
cgactctacccagaactcccgtctcaactggaactagtaccatttactaaagaacagcta
aaaatcttggagcctggttcatggctggaaaatgttgagtcatatttagaagaatttgac
agcatggctcatcaagacaggcatgaattttatgagttgcttttgaactactcacgatgt
aggaagcaactgctgctggctgaagctgagctgcttactctgacatctgattgccaaaat
gctaaaagtcggctgtggcagtttaaggaggaacaaatgtctgtacagggtatctgtgca
gatcaagtgaaagttttcagctatcatcgctaccaaagagtagaaatgaatgaaaatgca
ctggtggagctaaagaagctattcgatgccaaatctgagcacctccaccagaccctggcc
cttcattcttatacttctgtgctctcaagattgcaagtggagtcttacatctatgcattg
ctcagtagttcagctgttctgagatcttcagcaattcaccagcaaggccgagcgtctaag
cagacagaaagcattccctctgatctgtgtcaactaaaggaatgcattagtgtcttattc
atgttcaccaggagagttaatgaagatactcagtttcatgatgatattcttctctggctg
cagaaattggtatccgtgctacaaagagttggctgtcctggagatcacctcttccttcta
aaccatattcttcgatgccccgctggtgttagtaaatgggctgttccttttatccagatc
aaagtgttgcataacccatcaggggtctttcattttatgcaatcccttgccctgctgatg
tctcctgtcaaaaatcgagctgagtttatgtgccacatgaagcccagcgagcggaagcca
tcctcctcagggcctgggtctgggacttggacgctagtagacgaaggaggagaagaggat
gaagaccctgagaccagttggattctccttaatgaagatgatttggttaccattttagca
cagttcccctttcatgaactctttcagcatcttcttgggtttaaagcaaaaggtgattat
ttacctgaaacaacaagacctcaagagatgatgaaaatttttgcctttgccaactcacta
gtggaacttctggctgtggggttagaaacctttaatagagcacgctataggcagtttgtg
aagcgaattggttatatgatcaggatgactcttggttatgtaagtgaccattgggcacag
tatgtgagccataaccaaggctcaggattggcccaacagccctactctatggagaaacta
caggttgaatttgatgaactgtttttgagggctgtcctacatgtgctgaaggccaaaaga
cttggcatttggctgtttatgtccgagatgccctttgggactctgtctgtgcaaatgctg
tggaagctcttctacctcatgcaccaggtggagagcgagaacctgcagcagctctcctcc
tccctgcagcccgcccagtgcaagcagcagctccaagacccagaacattttaccaacttt
gagaagtgtctttcttctatgaatagctcagaagagatttgccttctgactacctttgct
cagatggctcaggccagaagaaccaatgtggacgaagacttcataaaaattattgttctg
gagatatatgaggtatcttatgtcaccttgtctaccagagagactttttcaaaggttggt
cgagagcttttagggactatcacagctgttcaccctgagataatttccgtccttctggat
agagttcaagagaccattgaccaggttggaatggtttctctatacttgtttaaagaactg
cctttgtatctttggcaaccttctgcatctgagatagcggtgattcgggattggttattg
aattacaacctgacagtggtgaagaataaactggcctgtgttattcttgaaggactgaat
tggggatttgctaaacaggctacccttcatctggatcaagcagtccatgctgaagtggct
ttaatggttcttgaagcttatcagaagtaccttgcacagaagccatatgctgggattctc
tctgaaagtatgaagcaggtttcatatttggccagtattgttcgatatggagagacaccc
gagacctcatttaaccaatgggcctggaatttaatcttgaggctaaaactgcacaaaaac
gattatggaatacagccgaattgtccagctgttcccttctccgtcactgtgcctgacatg
acagagtcacccacgtttcatcctctcttgaaggctgtgaaagcgggcatgcccattggc
tgttatctagccttatctatgacagctgtgggccacagcattgagaagttctgtgcagaa
ggcatcccactattgggaattctggtccagtcaagacatttgagaacagtggttcatgtc
ctggataagattctgcctttattttacccttgccagtattaccttctgaagaatgagcag
tttttatcgcatctcctcttgttcctacacttggacagcggtgtccctcagggtgtcaca
caacaggtcacccacaaggtggcacagcacctgacaggagccagccatggggacaacgtg
aagcttctcaacagcatgatccaggcacacatatctgtaagcactcagcccaatgaagtg
ggccccgttgctgtgttggagttctgggttcaggctctcataagccagcatctctggtac
cgagaacaacctatcctcttcctcatggaccacttgtgtaaagcagcttttcagctgatg
caggaagactgcatacagaaattactctaccaacaacataagaatgccttgggttaccac
tgtgaccggagtctgctctcatctttggtaagctggattgtggcaggcaacatcactcct
tcctttgtggagggcttggccacgcccactcaggtctggtttgcctggacagtgctcaac
atggaatccatctttgaagaggactcccagctccggagagttattgaaggggaattggtg
ataaactctgctttcacccctgaccaagctctgaagaaagcccagacccagctgaagctc
cccatcgtgccatccctccagaggctgctgatttatcgctgggcccaccaggctctggtc
acaccttctgatcaccccctcctgccactcatttggcagaagttcttccttctgtatctt
caccgtccgggaccacagtatgggttacccatagatggttgtattggaagaaggtttttt
caaagtcctgctcatatcaatttgttgaaagaaatgaagagacgtttgaccgaggtggct
gacttccaccatgctgcaagcaaggccctccgtgttccagcagagggcagtgaagggctg
ccagagagccactctggcacccctggttacctgacttcaccagaactgcacaaggagctg
gtgaggctcttcaatgtatatatattatggctagaagatgagaattttcaaaaaggagat
acctatatcccttctctaccaaagcattatgatattcacaggctagcaaaagtgatgcag
aatcagcaggatctgtggatggagtatttgaacatggagcgcatctatcatgagtttcag
gagactgttggtctgtggacacaggccaagcttgagtcccattccacaccctgcagtttg
tccgtgcagctggacttcactgatcctttgctggctaaagaaagggttttaagtaacttg
cggaagcatgaggctccccagcctccccttgctctgcacccgacgaagcctcctgtgcca
gttatttcctctgctgtgctattgagtcagaaggacgccacccagctggtgtgcacagac
ctgaatctgttgcaacagcaggccagaaccgcagctcttcgggaatctcagcaggttgct
ctggatggtgagctgttagacacaatgccaaagcagtatgtgaatcgtgaagaacagacc
acactacatttggagtgcagaggcagcagcggtaagaaatgccaaggagccgcagttgtc
acggttcagtttgaaggcatgcataagaatgaagccataagccaacagcttcatgtttta
cggaaggaagtgaagcagttgcaagcagaagctgctaaaccaccatcacttaatattgtg
gaagctgctgtacatgcagaaaacttgatcacggccttagtgaatgcctacaagttgcag
cctacacctgggattcagaaagttggcattagccttttctttactattgtggattacgtc
agcgatgagacgcagcgtcatcccccaacaaggcagttctttacttcatgtattgagatc
ttgggacaggtatttatcagtggcattaaatcagagtgcagaaaagtacttgaaaccatt
ctgaagaacagcaggctctgctccctgctgtctcctttcttcactcccaatgctgcacct
gcagagttcatacagctgtatgagcaagtggtgaagtttctaagtgaggacaacagtgat
atgattttcatgctgctaaccaagttcgatcttaaacaatggttaagcgccactaaacct
cctctgtctgatcgtaccaggcttctggagtccattcacttggcacttactgcctggggc
cttgaaccagatgaggatattttgatgccatttaatcttttctgtaagcactggacttat
cttcttctctaccagtttcctgaccagtacagtgacattctcaggctgcttatgcaaagc
tccgcggagcagcttctgagccccgagtgttggaaggccactctgagagccctgggctgc
tgcgcccccagctgccagcagggggcagcgtccaccgagggcgccgtgcttcccagctct
tctgatgctctcttgtcagacaagcaggtaatggagactatacagtggctttcagacttt
ttttataagcttcggttatccaagatggactttaaaagctttggtttattctcaaaatgg
agtccttatatggctgatgtgaagacattcttgggctaccttgtgaaaaggctgattgac
ttagaaatgacctgtttggcccaagacccaactgccagcaggaaaacagtgctgaaatcc
ctacattcagtaatcattcagctctttaagccatggatcctggttttagaggacaacgaa
agcagccaacagcggcattacccctggctagagagtgatactgtggtggcctcaagcatt
gtgcagctgttcactgactgtattgactcactgcatgagagttttaaagataagctgttg
ccaggtgatgcaggagccctttggttgcacctgatgcattattgtgaagcatgtacagca
cccaaaatgccagagttcattctgtacgctttccatagcacgtaccggaaactgccatgg
aaggacctgcaccctgaccagatgctcatggaggccttcttcaaagtggaacgaggaagc
cccaagagctgtttcttatttttggggtctgtactctgtgaagtcaactgggttagtgtg
ctctctgatgcctggaattccagtccccacccagaaacccgcagcatgattgtctgcctc
cttttcatgatgattttattggcaaaggaagttcaactggtagaccaaacagattcacct
ttacttagtctccttggacagacaagctcactttcatggcatcttgtggatattgtgtcg
taccagagtgtgctaagttatttcagcagccattacccgccgtccatcatcctggcaaaa
gaatcttatgctgaattaatcatgaagctcctaaaagtgtctgcgggcctttctattcct
actgacagccagaagcatcttgatgcagttccaaaatgccaagcttttactcatcagatg
gttcaattcctcagcaccctggaacaaaatggaaaaatcaccttagcagtcctagaacag
gaaatgtctaagctcttagacgatatcattgtctttaacccgcccgacatggacagccag
acccgccacatggccctcagcagcctctttatggaagtcctgatgatgatgaacaacgcg
actattccaacagcagagttccttcggggcagtatccggacctggattggccaaaaaatg
catgggctggtggtgctgccccttttaacagcagcctgccagagcctggcgtccgtccgc
cacatggctgagactacagaagcctgcatcactgcctacttcaaagaaagccctctcaat
cagaattcaggatggggacccattctggtatcccttcaggttcccgagctcaccatggaa
gagttcctgcaggagtgcctcaccttgggcagttacttgactctttacgtctacttgctt
cagtgtttaaacagcgaacagactttaaggaatgaaatgaaagtgctgctcatcttaagc
aagtggctggaacaggtgtacccaagctccgtggaggaagaggcaaagctgtttttgtgg
tggcaccaagtccttcagctctccctcattcagacagagcagaatgactccgtcctgaca
gaatctgtcattcgaattctgctcttggttcagagcaggcagaacctcgtggctgaggag
agactcagctctgggatcctgggggcaattgggtttggccggaagtcgcctttgtctaac
aggttccgagtggttgcccgaagcatggctgccttcctttcagttcaggttcctatggaa
gatcagatccgtttgaggcctggctctgaattacatctgacccccaaagctcagcaggct
ctgaatgctcttgaatccatggcatcaagtaagcagtatgttgaataccaggatcaaata
ttgcaagccacccaatttataaggcatcctggccattgccttcaagatgggaaaagcttc
ttggctcttctcgttaactgtctgtatccagaagtgcattatttggaccacatacgatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (42)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (39)   
DNA sequence (65)   
   RefSeq(nuc) (39)   
   GenBank (13)   
   EMBL (13)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (145)   

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