KEGG   Homo sapiens (human): 5800
Entry
5800              CDS       T01001                                 
Symbol
PTPRO, GLEPP1, NPHS6, PTP-OC, PTP-U2, PTPROT, PTPU2, R-PTP-O
Name
(RefSeq) protein tyrosine phosphatase receptor type O
  KO
K18035  receptor-type tyrosine-protein phosphatase O [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Disease
H01657  Nephrotic syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5800 (PTPRO)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     5800 (PTPRO)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Receptor PTPs
    5800 (PTPRO)
SSDB
Motif
Pfam: Y_phosphatase fn3 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 5800
NCBI-ProteinID: NP_109592
OMIM: 600579
HGNC: 9678
Ensembl: ENSG00000151490
UniProt: Q16827
Structure
Position
12:15322508..15598331
AA seq 1216 aa
MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSLEASDVISPASVYVVKI
TGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNGNVVTKPSRSITVLTKPLP
VTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEGKDFRTMLYKDFFKGKTVFNH
WLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNW
EEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWPDFNSSDYETTSQPYWW
DSASAAPESEDEFVSVLPMEYENNSTLSETEKSTSGSFSFFPVQMILTWLPPKPPTAFDG
FHIHIEREENFTEYLMVDEEAHEFVAELKEPGKYKLSVTTFSSSGSCETRKSQSAKSLSF
YISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQR
LEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYP
LGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLP
AWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDL
SHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVK
LEPAPPKSLFAVNKTQTSVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTI
SSLLPATAYNCSVTSFSHDSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVT
LIILRKKHLQMARECGAGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFY
INPWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLP
LNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRND
FWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRH
FRINYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGV
GRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK
QQFCISDVIYENVSKS
NT seq 3651 nt   +upstreamnt  +downstreamnt
atggggcacctgcccacggggatacacggcgcccgccgcctcctgcctctgctctggctc
tttgtgctgttcaagaatgctacagctttccatgtaactgtccaagatgataataacatc
gttgtctcattagaagcttcagacgtcatcagtccagcatctgtgtatgttgtgaagata
actggtgaatccaaaaattatttcttcgaatttgaggaattcaacagcactttgcctcct
cctgttattttcaaggccagttatcatggcctttattatataatcactctggtagtggta
aatggaaatgtggtgaccaagccatccagatcaatcactgtgttaacaaaacctctacct
gtaaccagtgtttccatatatgactataaaccttctcctgaaacaggagtcctgtttgaa
atacattatccagaaaaatataacgttttcacaagagtgaacattagctactgggaaggt
aaagacttccggacaatgctatataaagatttctttaagggaaaaacagtatttaatcac
tggctgccaggaatgtgttatagtaatatcacctttcagctggtatctgaggcaactttt
aataaaagtacccttgttgagtacagtggtgtcagtcacgaacccaaacagcacagaact
gccccttatccacctcaaaatatttccgttcgtatcgtaaacttgaacaaaaacaactgg
gaagaacagagtggcaatttcccagaagaatccttcatgagatcacaagatacaatagga
aaagaaaaactcttccattttacagaagaaacccctgaaattccctcgggcaacatttct
tccggttggcctgattttaatagcagtgactatgaaactacgtctcagccatattggtgg
gacagtgcatctgcagctcctgaaagtgaagatgaatttgtcagcgtacttcccatggaa
tacgaaaataacagtacactcagtgagacagagaagtcaacatcaggctctttctccttt
ttccctgtgcaaatgatattgacctggttaccacccaaaccacccactgcttttgatggg
ttccatatccatattgaacgagaagagaactttactgaatatttgatggtggatgaagaa
gcacatgaatttgttgcagaactgaaggaacctgggaaatataagttatctgtgacaacc
tttagttcctcaggatcttgtgaaactcgaaaaagtcagtcagcaaaatcactcagcttt
tatatcagtccttcaggagagtggattgaagaactgaccgagaagccgcagcacgtgagt
gtccacgttttaagctcaaccactgccttgatgtcctggacatcttcccaagagaactac
aacagcaccattgtgtctgtggtgtcgctgacctgccagaaacaaaaggagagccagagg
cttgaaaagcagtactgcactcaggtgaactcaagcaaacctattattgaaaatctggtt
cctggtgcccagtaccaggttgtaatatacctaaggaaaggccctttgattggaccacct
tcagatcctgtgacatttgctattgttcccacaggaataaaggatttaatgctctatcct
ttgggtcctacggccgtggttctgagctggaccagaccttatttaggcgtgttcagaaaa
tacgtggttgaaatgttttatttcaaccctgctacaatgacatcagagtggaccacctac
tatgaaatagcagcaactgtttccttaactgcatccgtgagaatagctaatctgctgcca
gcatggtactacaacttccgggttaccatggtgacgtggggagatccagaattgagctgc
tgtgacagctctaccatcagcttcataacagccccagtggctccggaaatcacttctgtg
gaatatttcaacagtctgttatatatcagttggacatatggggatgatacaacggacttg
tcccattctagaatgcttcactggatggtggttgcagaaggaaaaaagaaaattaaaaag
agtgtaacacgcaatgtcatgactgcaattctcagcttgcctccaggcgacatctataac
ctctcagtaactgcttgtactgaaagaggaagtaatacctccatgctccgccttgtcaag
ctagaaccagctccacccaaatcactcttcgcagtgaacaaaacccagacttcagtgact
ttgctgtgggtggaagagggagtagctgatttctttgaagttttctgtcaacaagttggc
tccagtcagaaaaccaaacttcaggaaccagttgctgtttcttcccatgtcgtgaccatc
tccagccttcttcctgccactgcctacaattgtagtgtcaccagctttagccatgacagc
cccagtgtccctacgttcatagccgtctcaacaatggttacagagatgaatcccaatgtg
gtagtgatctccgtgctggccatccttagcacacttttaattggactgttgcttgttacc
ctcattattcttaggaaaaagcatctgcagatggctagggagtgtggagctggtacattt
gtcaattttgcatccttagagagggatggaaagcttccatacaactggcgtaggagtata
tttgctttcttaaccctgctaccctcatgtctttggactgattatcttttggcattttat
attaatccttggagtaaaaatggtttaaagaagaggaaactgacaaacccggttcaactg
gatgactttgatgcctatattaaggatatggccaaagactctgactataaattttctctt
cagtttgaggagttgaaattgattggactggatatcccacactttgctgcagatcttcca
ctgaatcgatgtaaaaaccgttacacaaacatcctaccatatgacttcagccgtgtgaga
ttagtctccatgaatgaagaggaaggtgcagactacatcaatgccaactatattcctgga
tacaactcaccccaggagtatattgccacccaggggccactgcctgaaaccagaaatgac
ttctggaagatggtcctgcaacaaaagtctcagattattgtcatgctcactcagtgtaat
gagaaaaggagggtgaaatgtgaccattactggccattcacggaagaacctatagcctat
ggagacatcactgtggagatgatttcagaggaagagcaggacgactgggcctgtagacac
ttccggatcaactatgctgacgagatgcaggatgtgatgcattttaactacactgcatgg
cctgatcatggtgtgcccacagcaaatgctgcagaaagtatcctgcagtttgtacacatg
gtccgacagcaagctaccaagagcaaaggtcccatgatcattcactgcagtgctggcgtg
ggacggacaggaacattcattgccctggacaggctcttgcagcacattcgggatcatgag
tttgttgacatcttagggctggtgtcagaaatgaggtcataccggatgtctatggtacag
acagaggagcagtacatttttatccatcagtgtgtgcaactgatgtggatgaagaagaag
cagcagttctgcatcagtgatgtcatatacgagaatgttagcaagtcctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (45)   
   RefSeq(nuc) (13)   
   GenBank (16)   
   EMBL (16)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (81)   

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