KEGG   Homo sapiens (human): 5871
Entry
5871              CDS       T01001                                 
Symbol
MAP4K2, BL44, GCK, RAB8IP
Name
(RefSeq) mitogen-activated protein kinase kinase kinase kinase 2
  KO
K04414  mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    5871 (MAP4K2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    5871 (MAP4K2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     5871 (MAP4K2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: STE group
  STE20 family
   5871 (MAP4K2)
SSDB
Motif
Pfam: Pkinase CNH PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like
Other DBs
NCBI-GeneID: 5871
NCBI-ProteinID: NP_004570
OMIM: 603166
HGNC: 6864
Ensembl: ENSG00000168067
UniProt: Q12851
Position
11:complement(64784918..64803214)
AA seq 820 aa
MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQ
EITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREA
LKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAP
EVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKT
RWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASDPHLGTPSPE
DCELETYDMFPDTIHSRGQHGPAERTPSEIQFHQVKFGAPRRKETDPLNEPWEEEWTLLG
KEELSGSLLQSVQEALEERSLTIRSASEFQELDSPDDTMGTIKRAPFLGPLPTDPPAEEP
LSSPPGTLPPPPSGPNSSPLLPTAWATMKQREDPERSSCHGLPPTPKVHMGACFSKVFNG
CPLRIHAAVTWIHPVTRDQFLVVGAEEGIYTLNLHELHEDTLEKLISHRCSWLYCVNNVL
LSLSGKSTHIWAHDLPGLFEQRRLQQQVPLSIPTNRLTQRIIPRRFALSTKIPDTKGCLQ
CRVVRNPYTGATFLLAALPTSLLLLQWYEPLQKFLLLKNFSSPLPSPAGMLEPLVLDGKE
LPQVCVGAEGPEGPGCRVLFHVLPLEAGLTPDILIPPEGIPGSAQQVIQVDRDTILVSFE
RCVRIVNMQGEPTATLAPELTFDFPIETVVCLQDSVLAFWSHGMQGRSLDTNEVTQEITD
ETRIFRVLGAHRDIILESIPTDNPEAHSNLYILTGHQSTY
NT seq 2463 nt   +upstreamnt  +downstreamnt
atggcgctgctgcgggatgtgtcgctgcaggacccgcgggaccgcttcgagctgctgcag
cgcgtgggggccgggacctatggcgacgtctacaaggcccgcgacacggtcacgtccgaa
ctggccgccgtgaagatagtcaagctagacccaggggacgacatcagctccctccagcag
gaaatcaccatcctgcgtgagtgccgccaccccaatgtggtggcctacattggcagctac
ctcaggaatgaccgcttgtggatctgcatggagttctgcggagggggctccctgcaggag
atttaccatgccactgggcccctggaggagcggcagattgcctacgtctgccgagaggca
ctgaaggggctccaccacctgcattctcaggggaagatccacagagacatcaagggagcc
aaccttctcctcactctccagggagatgtcaaactggctgactttggggtgtcaggcgag
ctgacagcgtctgtggccaagaggaggtctttcattgggactccctactggatggctccc
gaggtggctgctgtggagcgcaaaggtggctacaatgagctatgtgacgtctgggccctg
ggcatcactgccattgagctgggcgagctgcagccccctctgttccacctgcaccccatg
agggccctgatgctcatgtcgaagagcagcttccagccgcccaaactgagagataagact
cgctggacccagaatttccaccactttctcaaactggccctgaccaagaatcctaagaag
aggccgacagcagagaagctcctgcagcacccgttcacgactcagcagctccctcgggcc
ctcctcacacagctgctggacaaagccagtgaccctcatctggggaccccctcccctgag
gactgtgagctggagacctatgacatgtttccagacaccattcactcccgggggcagcac
ggcccagccgagaggaccccctcggagatccagtttcaccaggtgaaatttggcgcccca
cgcaggaaggaaactgacccactgaatgagccgtgggaggaagagtggacactactggga
aaggaagagttgagtgggagcctgctgcagtcggtccaggaggccctggaggaaaggagt
ctgactattcggtcagcctcagaattccaggagctggactccccagacgataccatggga
accatcaagcgggccccgttcctagggccactccccactgaccctccagcagaggagcct
ctgtccagtcccccaggaaccctgcccccacctccttcaggccccaacagctccccactg
ctgcccacggcctgggccaccatgaagcagcgggaggatcctgagaggtcatcctgccac
gggctccccccaactcccaaggtgcatatgggcgcctgcttctccaaggtcttcaatggc
tgccccctgcggatccacgctgctgtcacctggattcaccctgttactcgggaccagttc
ctggtggtaggggccgaggaaggcatctacacactcaacctgcatgaactgcatgaggat
acgctggagaagctgatttcacatcgctgctcctggctctactgcgtgaacaacgtgctg
ctgtcactctcagggaaatccacgcacatctgggcccatgacctcccaggcctgtttgag
cagcggaggctacagcaacaggttcccctctccatccccaccaaccgcctcacccagcgc
atcatccccaggcgctttgctctgtccaccaagattcctgacaccaaaggctgcttgcag
tgtcgtgtggtgcggaacccctacacgggtgccaccttcctgctggccgccctgcccacc
agcctgctcctgctgcagtggtatgagccgctgcagaagtttctgctgctgaagaacttc
tccagccctctgcccagcccagctgggatgctggagccgctggtgctggatgggaaggag
ctgccgcaggtgtgtgttggggccgaggggcctgaggggcccggctgccgcgtcctgttc
catgtcctgcccctggaggctggcctgacgcccgacatcctcatcccacctgaggggatc
ccaggctcggcccagcaggtgatccaggtggacagggacacaatcctagtcagctttgaa
cgctgtgtgaggattgtcaacatgcagggcgagcccacggccacactggcacctgagctg
acctttgatttccccatcgagactgtggtgtgcctgcaggacagtgtgctggccttctgg
agccatgggatgcaaggccgaagcctggataccaatgaggtgacccaggagatcacagat
gaaacaaggatcttccgagtgcttggggcccacagagacatcatcctggagagcattccc
actgacaacccagaggcgcacagcaacctctacatcctcacgggccaccagagcacctac
taa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (20)   
   RefSeq(nuc) (2)   
   GenBank (9)   
   EMBL (9)   
Protein domain (6)   
   Pfam (6)   
All databases (52)   

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