KEGG   Homo sapiens (human): 5932
Entry
5932              CDS       T01001                                 
Symbol
RBBP8, COM1, CTIP, JAWAD, JWDS, RIM, SAE2, SCKL2
Name
(RefSeq) RB binding protein 8, endonuclease
  KO
K20773  DNA endonuclease RBBP8 [EC:3.1.-.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03440  Homologous recombination
Network
nt06506  Double-strand break repair
  Element
N01446  DNA end resection and RPA loading
Disease
H00992  Seckel syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    5932 (RBBP8)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5932 (RBBP8)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    BRCA1-C complex
     5932 (RBBP8)
SSDB
Motif
Pfam: CtIP_N SAE2
Other DBs
NCBI-GeneID: 5932
NCBI-ProteinID: NP_002885
OMIM: 604124
HGNC: 9891
Ensembl: ENSG00000101773
UniProt: Q99708
Structure
Position
18:22914139..23026486
AA seq 897 aa
MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF
TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL
MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE
NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG
TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR
NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK
TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN
RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS
MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD
GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL
DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG
ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM
NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY
FKGDERETSLQNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRF
RYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT
NT seq 2694 nt   +upstreamnt  +downstreamnt
atgaacatctcgggaagcagctgtggaagccctaactctgcagatacatctagtgacttt
aaggacctttggacaaaactaaaagaatgtcatgatagagaagtacaaggtttacaagta
aaagtaaccaagctaaaacaggaacgaatcttagatgcacaaagactagaagaattcttc
accaaaaatcaacagctgagggaacagcagaaagtccttcatgaaaccattaaagtttta
gaagatcggttaagagcaggcttatgtgatcgctgtgcagtaactgaagaacatatgcgg
aaaaaacagcaagagtttgaaaatatccggcagcagaatcttaaacttattacagaactt
atgaatgaaaggaatactctacaggaagaaaataaaaagctttctgaacaactccagcag
aaaattgagaatgatcaacagcatcaagcagctgagcttgaatgtgaggaagacgttatt
ccagattcaccgataacagccttctcattttctggcgttaaccggctacgaagaaaggag
aacccccatgtccgatacatagaacaaacacatactaaattggagcactctgtgtgtgca
aatgaaatgagaaaagtttccaagtcttcaactcatccacaacataatcctaatgaaaat
gaaattctagtagctgacacttatgaccaaagtcaatctccaatggccaaagcacatgga
acaagcagctatacccctgataagtcatcttttaatttagctacagttgttgctgaaaca
cttggacttggtgttcaagaagaatctgaaactcaaggtcccatgagcccccttggtgat
gagctctaccactgtctggaaggaaatcacaagaaacagccttttgaggaatctacaaga
aatactgaagatagtttaagattttcagattctacttcaaagactcctcctcaagaagaa
ttacctactcgagtgtcatctcctgtatttggagctacctctagtatcaaaagtggttta
gatttgaatacaagtttgtccccttctcttttacagcctgggaaaaaaaaacatctgaaa
acactcccttttagcaacacttgtatatctagattagaaaaaactagatcaaaatctgaa
gatagtgcccttttcacacatcacagtcttgggtctgaagtgaacaagatcattatccag
tcatctaataaacagatacttataaataaaaatataagtgaatccctaggtgaacagaat
aggactgagtacggtaaagattctaacactgataaacatttggagcccctgaaatcattg
ggaggccgaacatccaaaaggaagaaaactgaggaagaaagtgaacatgaagtaagctgc
ccccaagcttcttttgataaagaaaatgctttcccttttccaatggataatcagttttcc
atgaatggagactgtgtgatggataaacctctggatctgtctgatcgattttcagctatt
cagcgtcaagagaaaagccaaggaagtgagacttctaaaaacaaatttaggcaagtgact
ctttatgaggctttgaagaccattccaaagggcttttcctcaagccgtaaggcctcagat
ggcaactgcacgttgcccaaagattccccaggggagccctgttcacaggaatgcatcatc
cttcagcccttgaataaatgctctccagacaataaaccatcattacaaataaaagaagaa
aatgctgtctttaaaattcctctacgtccacgtgaaagtttggagactgagaatgtttta
gatgacataaagagtgctggttctcatgagccaataaaaatacaaaccaggtcagaccat
ggaggatgtgaacttgcatcagttcttcagttaaatccatgtagaactggtaaaataaag
tctctacaaaacaaccaagatgtatcctttgaaaatatccagtggagtatagatccggga
gcagacctttctcagtataaaatggatgttactgtaatagatacaaaggatggcagtcag
tcaaaattaggaggagagacagtggacatggactgtacattggttagtgaaaccgttctc
ttaaaaatgaagaagcaagagcagaagggagaaaaaagttcaaatgaagaaagaaaaatg
aatgatagcttggaagatatgtttgatcggacaacacatgaagagtatgaatcctgtttg
gcagacagtttctcccaagcagcagatgaagaggaggaattgtctactgccacaaagaaa
ctacacactcatggtgataaacaagacaaagtcaagcagaaagcgtttgtggagccgtat
tttaaaggtgatgaaagagagactagcttgcaaaattttcctcatattgaggtggttcgg
aaaaaagaggagagaagaaaactgcttgggcacacgtgtaaggaatgtgaaatttattat
gcagatatgccagcagaagaaagagaaaagaaattggcttcctgctcaagacaccgattc
cgctacattccacccaacacaccagagaatttttgggaagttggttttccttccactcag
acttgtatggaaagaggttatattaaggaagatcttgatccttgtcctcgtccaaaaaga
cgtcagccttacaacgcaatattttctccaaaaggcaaggagcagaagacatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
Protein sequence (26)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (40)   
   RefSeq(nuc) (24)   
   GenBank (8)   
   EMBL (8)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (106)   

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