KEGG   Homo sapiens (human): 60495
Entry
60495             CDS       T01001                                 
Symbol
HPSE2, HPA2, HPR2, UFS, UFS1
Name
(RefSeq) heparanase 2 (inactive)
  KO
K07965  heparanase 2 [EC:3.2.1.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00531  Glycosaminoglycan degradation
hsa01100  Metabolic pathways
hsa05205  Proteoglycans in cancer
Module
hsa_M00078  Heparan sulfate degradation
Disease
H00753  Urofacial syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    60495 (HPSE2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    60495 (HPSE2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    60495 (HPSE2)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Enzymes
   60495 (HPSE2)
SSDB
Motif
Pfam: Glyco_hydro_79n
Other DBs
NCBI-GeneID: 60495
NCBI-ProteinID: NP_068600
OMIM: 613469
HGNC: 18374
Ensembl: ENSG00000172987
UniProt: Q8WWQ2 Q2M1H9
Position
10:complement(98457077..99315951)
AA seq 592 aa
MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQAGDRRPLPVDRAAGLKEKTL
ILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRT
DFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREK
AAQMHLVLLKEQFSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSS
ALSLLKYSASKKYNISWELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRAS
LYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQ
IRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIR
HSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRI
YAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSKSV
QLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR
NT seq 1779 nt   +upstreamnt  +downstreamnt
atgagggtgctttgtgccttccctgaagccatgccctccagcaactcccgcccccccgcg
tgcctagccccgggggctctctacttggctctgttgctccatctctccctttcctcccag
gctggagacaggagacccttgcctgtagacagagctgcaggtttgaaggaaaagaccctg
attctacttgatgtgagcaccaagaacccagtcaggacagtcaatgagaacttcctctct
ctgcagctggatccgtccatcattcatgatggctggctcgatttcctaagctccaagcgc
ttggtgaccctggcccggggactttcgcccgcctttctgcgcttcgggggcaaaaggacc
gacttcctgcagttccagaacctgaggaacccggcgaaaagccgcgggggcccgggcccg
gattactatctcaaaaactatgaggatgacattgttcgaagtgatgttgccttagataaa
cagaaaggctgcaagattgcccagcaccctgatgttatgctggagctccaaagggagaag
gcagctcagatgcatctggttcttctaaaggagcaattctccaatacttacagtaatctc
atattaacagccaggtctctagacaaactttataactttgctgattgctctggactccac
ctgatatttgctctaaatgcactgcgtcgtaatcccaataactcctggaacagttctagt
gccctgagtctgttgaagtacagcgccagcaaaaagtacaacatttcttgggaactgggt
aatgagccaaataactatcggaccatgcatggccgggcagtaaatggcagccagttggga
aaggattacatccagctgaagagcctgttgcagcccatccggatttattccagagccagc
ttatatggccctaatattgggcggccgaggaagaatgtcatcgccctcctagatggattc
atgaaggtggcaggaagtacagtagatgcagttacctggcaacattgctacattgatggc
cgggtggtcaaggtgatggacttcctgaaaactcgcctgttagacacactctctgaccag
attaggaaaattcagaaagtggttaatacatacactccaggaaagaagatttggcttgaa
ggtgtggtgaccacctcagctggaggcacaaacaatctatccgattcctatgctgcagga
ttcttatggttgaacactttaggaatgctggccaatcagggcattgatgtcgtgatacgg
cactcattttttgaccatggatacaatcacctcgtggaccagaattttaacccattacca
gactactggctctctctcctctacaagcgcctgatcggccccaaagtcttggctgtgcat
gtggctgggctccagcggaagccacggcctggccgagtgatccgggacaaactaaggatt
tatgctcactgcacaaaccaccacaaccacaactacgttcgtgggtccattacacttttt
atcatcaacttgcatcgatcaagaaagaaaatcaagctggctgggactctcagagacaag
ctggttcaccagtacctgctgcagccctatgggcaggagggcctaaagtccaagtcagtg
caactgaatggccagcccttagtgatggtggacgacgggaccctcccagaattgaagccc
cgcccccttcgggccggccggacattggtcatccctccagtcaccatgggcttttatgtg
gtcaagaatgtcaatgctttggcctgccgctaccgataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (27)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (44)   
   RefSeq(nuc) (24)   
   GenBank (10)   
   EMBL (10)   
Protein domain (1)   
   Pfam (1)   
All databases (95)   

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