KEGG   Homo sapiens (human): 641371
Entry
641371            CDS       T01001                                 
Symbol
ACOT1, ACH2, CTE-1, LACH2
Name
(RefSeq) acyl-CoA thioesterase 1
  KO
K01068  acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00062  Fatty acid elongation
hsa01040  Biosynthesis of unsaturated fatty acids
hsa01100  Metabolic pathways
hsa04913  Ovarian steroidogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    641371 (ACOT1)
   01040 Biosynthesis of unsaturated fatty acids
    641371 (ACOT1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    641371 (ACOT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    641371 (ACOT1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.2  palmitoyl-CoA hydrolase
     641371 (ACOT1)
Lipid biosynthesis proteins [BR:hsa01004]
 Fatty acid synthase
  Component type
   641371 (ACOT1)
SSDB
Motif
Pfam: BAAT_C Bile_Hydr_Trans DLH Peptidase_S9 FSH1
Other DBs
NCBI-GeneID: 641371
NCBI-ProteinID: NP_001032238
OMIM: 614313
HGNC: 33128
Ensembl: ENSG00000184227
UniProt: Q86TX2 E9KL42
Position
14:73490933..73543796
AA seq 421 aa
MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGEL
DLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLL
CRVRHERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAG
KGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLS
MASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPL
EGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGH
YIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSK
V
NT seq 1266 nt   +upstreamnt  +downstreamnt
atggcggcgacgctgatcctggagcccgcgggccgctgctgctgggacgaaccggtgcga
atcgccgtgcgcggcctagccccggagcagccggtcacgctgcgcgcgtccctgcgcgac
gagaagggcgcgcttttccaggcccacgcgcgctaccgcgccgacacccttggcgagctg
gacctggagcgcgcgcccgcgctgggcggcagcttcgcggggcttgagcccatggggctg
ctctgggccttggagcccgagaaacccttggtgcggctggtgaagcgcgacgtgcgaacg
cccttggccgtggagctggaggtgctggatggccacgaccccgaccccgggcggctgctg
tgccgggtgcggcacgagcgctacttcctcccgcccggggtgcggcgcgagccggtgcgc
gcgggccgggtgcgaggcacgctcttcctgccgccagaacctgggccctttcctggcatt
gtggacatgttcggaactggaggtggcctgctggagtatcgggctagtctgctggctggg
aagggttttgctgtgatggctctggcttactataactatgaagacctccccaagaccatg
gagacgctccatctggagtactttgaagaagctgtgaactacttgctcagtcatcctgag
gtaaaaggtccaggagttgggctgcttggaatttccaaagggggtgagctctgcctttcc
atggcctctttcctgaagggcatcacggctgctgtcgtcatcaacggctctgtggccaat
gttgggggaaccttacgctacaagggcgagaccctgccccctgtgggcgtcaacagaaat
cgcatcaaggtgaccaaagatggctatgcagacattgtggatgtcctgaacagccctttg
gaaggacctgaccagaagagcttcattcctgtggaaagggcagagagcaccttcctgttc
ctggtaggtcaggatgaccacaactggaagagtgagttctatgctaatgaggcctgtaaa
cgcttgcaggcccatgggaggagaaagccccagatcatctgttacccagagacagggcac
tatattgagcctccttacttccccctgtgtcgggcttccctgcatgccttggtgggcagt
cctattatctggggaggggagcccagggctcatgccatggctcaggtggatgcttggaaa
caactccagactttcttccacaaacacttgggtggccacgaggggacaatcccatcaaaa
gtgtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical substance (26)   
   KEGG COMPOUND (26)   
Chemical reaction (13)   
   KEGG ENZYME (1)   
   KEGG REACTION (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (27)   
   RefSeq(nuc) (5)   
   GenBank (11)   
   EMBL (11)   
Protein domain (5)   
   Pfam (5)   
All databases (99)   

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