KEGG   Homo sapiens (human): 64754
Entry
64754             CDS       T01001                                 
Symbol
SMYD3, KMT3E, ZMYND1, ZNFN3A1, bA74P14.1
Name
(RefSeq) SET and MYND domain containing 3
  KO
K11426  [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00310  Lysine degradation
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    64754 (SMYD3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    64754 (SMYD3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase
     64754 (SMYD3)
    2.1.1.357  [histone H3]-lysine36 N-dimethyltransferase
     64754 (SMYD3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     64754 (SMYD3)
SSDB
Motif
Pfam: SET zf-MYND
Other DBs
NCBI-GeneID: 64754
NCBI-ProteinID: NP_001161212
OMIM: 608783
HGNC: 15513
Ensembl: ENSG00000185420
UniProt: Q9H7B4
Structure
Position
1:complement(245749347..246507279)
AA seq 428 aa
MEPLKVEKFATAKRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLM
RCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSES
EKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVIC
NSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYL
DMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHW
KWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRI
FFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEE
CDANIRAS
NT seq 1287 nt   +upstreamnt  +downstreamnt
atggagccgctgaaggtggaaaagttcgcaaccgccaagaggggaaacgggctgcgcgcc
gtgaccccgctgcgccccggagagctactcttccgctcggatcccttggcgtacacggtg
tgcaaggggagtcgtggcgtcgtctgcgaccgctgccttctcgggaaggaaaagctgatg
cgatgctctcagtgccgcgtcgccaaatactgtagtgctaagtgtcagaaaaaagcttgg
ccagaccacaagcgggaatgcaaatgccttaaaagctgcaaacccagatatcctccagac
tccgttcgacttcttggcagagttgtcttcaaacttatggatggagcaccttcagaatca
gagaagctttactcattttatgatctggagtcaaatattaacaaactgactgaagataag
aaagagggcctcaggcaactcgtaatgacatttcaacatttcatgagagaagaaatacag
gatgcctctcagctgccacctgcctttgacctttttgaagcctttgcaaaagtgatctgc
aactctttcaccatctgtaatgcggagatgcaggaagttggtgttggcctatatcccagt
atctctttgctcaatcacagctgtgaccccaactgttcgattgtgttcaatgggccccac
ctcttactgcgagcagtccgagacatcgaggtgggagaggagctcaccatctgctacctg
gatatgctgatgaccagtgaggagcgccggaagcagctgagggaccagtactgctttgaa
tgtgactgtttccgttgccaaacccaggacaaggatgctgatatgctaactggtgatgag
caagtatggaaggaagttcaagaatccctgaaaaaaattgaagaactgaaggcacactgg
aagtgggagcaggttctggccatgtgccaggcaatcataagcagcaattctgaacggctt
cccgatatcaacatctaccagctgaaggtgctcgactgcgccatggatgcctgcatcaac
ctcggcctgttggaggaagccttgttctatggtactcggaccatggagccatacaggatt
tttttcccaggaagccatcccgtcagaggggttcaagtgatgaaagttggcaaactgcag
ctacatcaaggcatgtttccccaagcaatgaagaatctgagactggcttttgatattatg
agagtgacacatggcagagaacacagcctgattgaagatttgattctacttttagaagaa
tgcgacgccaacatcagagcatcctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (29)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (27)   
DNA sequence (53)   
   RefSeq(nuc) (27)   
   GenBank (13)   
   EMBL (13)   
3D Structure (34)   
   PDB (34)   
Protein domain (2)   
   Pfam (2)   
All databases (156)   

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