KEGG   Homo sapiens (human): 6585
Entry
6585              CDS       T01001                                 
Symbol
SLIT1, MEGF4, SLIL1, SLIT-1, SLIT3
Name
(RefSeq) slit guidance ligand 1
  KO
K06838  slit 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    6585 (SLIT1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    6585 (SLIT1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Axon guidance molecules
   6585 (SLIT1)
SSDB
Motif
Pfam: LRR_8 LRR_4 LRR_5 EGF Laminin_G_2 LRRNT Laminin_G_1 hEGF LRRCT LRR_9 LRR_1 DL-JAG_EGF-like EGF_3 EGF_2
Other DBs
NCBI-GeneID: 6585
NCBI-ProteinID: NP_003052
OMIM: 603742
HGNC: 11085
Ensembl: ENSG00000187122
UniProt: O75093 A6H8V1
Position
10:complement(96998038..97185959)
AA seq 1534 aa
MALTPGWGSSAGPVRPELWLLLWAAAWRLGASACPALCTCTGTTVDCHGTGLQAIPKNIP
RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ
LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL
RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFT
QCSGPASLRGLNVAEVQKSEFSCSGQGEAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGL
TAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLN
SLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSL
AKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIETSGARCASPRRLANKRIGQI
KSKKFRCSAKEQYFIPGTEDYQLNSECNSDVVCPHKCRCEANVVECSSLKLTKIPERIPQ
STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ
LESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTL
QSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCE
EGQEEGGCLPRPQCPQECACLDTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQL
STFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLH
GNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPQDME
GKLLLTTPAKKFECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRD
CEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVC
VDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNC
SENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGA
NCVDQGNRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDN
GILLYNGDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQFHTVELVAFDQMVNL
SIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYIN
NELQDFTKTQMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGP
CHGHKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGA
HCVCDPGFSGELCEQESECRGDPVRDFHQVQRGYAICQTTRPLSWVECRGSCPGQGCCQG
LRLKRRKFTFECSDGTSFAEEVEKPTKCGCALCA
NT seq 4605 nt   +upstreamnt  +downstreamnt
atggcgctgactcccgggtgggggtcctcggcggggccggtccggccggagctctggctg
ctgctgtgggcagccgcgtggcgcctgggtgcctcggcgtgccccgccctctgcacctgc
accggaaccacggtggactgccacggcacggggctgcaggccattcccaagaatatacct
cggaacaccgagcgcctggaactcaatggcaacaacatcactcggatccataagaatgac
tttgcggggctcaagcagctgcgggtgctgcagctgatggagaaccagattggagcagtg
gaacgtggtgcttttgatgacatgaaggagctggagcggctgcgactgaaccgaaaccag
ctgcacatgttaccggaactgctgttccagaacaaccaggctttgtcaagactggacttg
agtgagaacgccatccaggccatccccaggaaagcttttcggggagctacggaccttaaa
aatttacagctggacaagaaccagatcagctgcattgaggaaggggccttccgtgctctg
cgggggctggaggtgctgaccctgaacaacaacaatatcaccaccatccccgtgtccagc
ttcaaccatatgcccaagctacggaccttccgcctgcactccaaccacctgttttgcgac
tgccacctggcctggctctcgcagtggctgaggcagcggccaaccatcgggctcttcacc
cagtgctcgggcccagccagcctgcgtggcctcaatgtggcagaggtccagaagagtgag
ttcagctgctcaggccagggagaagcggggcgcgtgcccacctgcaccctgtcctccggc
tcctgcccggccatgtgcacctgcagcaatggcatcgtggactgtcgtggaaaaggcctc
actgccatcccggccaacctgcccgagaccatgacggagatacgcctggagctgaacggc
atcaagtccatccctcctggagccttctcaccctacagaaagctacggaggatagacctg
agcaacaatcagatcgctgagattgcacccgacgccttccagggcctccgctccctgaac
tcgctggtcctctatggaaacaagatcacagacctcccccgtggtgtgtttggaggccta
tacaccctacagctcctgctcctgaatgccaacaagatcaactgcatccggcccgatgcc
ttccaggacctgcagaacctctcactgctctccctgtatgacaacaagatccagagcctc
gccaagggcactttcacctccctgcgggccatccagactctgcacctggcgcagaaccct
ttcatttgcgactgtaacctcaagtggctggcagacttcctgcgcaccaatcccatcgag
acgagtggtgcccgctgtgccagtccccggcgcctcgccaacaagcgcatcgggcagatc
aagagcaagaagttccggtgctcagccaaagagcagtacttcattccaggcacggaggat
taccagctgaacagcgagtgcaacagcgacgtggtctgtccccacaagtgccgctgtgag
gccaacgtggtggagtgctccagcctgaagctcaccaagatccctgagcgcatcccccag
tccacggcagaactgcgattgaataacaatgagatttccatcctggaggccactgggatg
tttaaaaaacttacacatctgaagaaaatcaatctgagcaacaacaaggtgtcagaaatt
gaagatggggccttcgagggcgcagcctctgtgagcgagctgcacctaactgccaaccag
ctggagtccatccggagcggcatgttccggggtctggatggcttgaggaccctaatgctg
cggaacaaccgcatcagctgcatccacaacgacagcttcacgggcctgcgcaacgtccgg
ctcctctcgctctacgacaaccagatcaccaccgtatccccaggagccttcgacaccctc
cagtccctctccacactgaatctcctggccaaccctttcaactgcaactgccagctggcc
tggctaggaggctggctacggaagcgcaagatcgtgacggggaacccgcgatgccagaac
cctgactttttgcggcagattcccctgcaggacgtggccttccctgacttcaggtgtgag
gaaggccaggaggaggggggctgcctgccccgcccacagtgcccacaggagtgcgcctgc
ctggacaccgtggtccgatgcagcaacaagcacctgcgggccctgcccaagggcattccc
aagaatgtcacagaactctatttggacgggaaccagttcacgctggttccgggacagctg
tctaccttcaagtacctgcagctcgtggacctgagcaacaacaagatcagttccttaagc
aattcctccttcaccaacatgagccagctgaccactctgatcctcagctacaatgccctg
cagtgcatcccgcctttggccttccagggactccgctccctgcgcctgctgtctctccac
ggcaatgacatctccaccctccaagagggcatctttgcagacgtgacctccctgtctcac
ctggccattggtgccaaccccctatactgtgactgccacctccgctggctgtccagctgg
gtgaagactggctacaaggaaccgggcattgctcgttgtgctgggccccaggacatggag
ggcaagctgctcctcaccacgcctgccaagaagtttgaatgccaaggtcctccaacgctg
gctgtccaggccaagtgtgatctctgcttgtccagtccgtgccagaaccagggcacctgc
cacaacgacccccttgaggtgtacaggtgcgcctgccccagcggctataagggtcgagac
tgtgaggtgtccctggacagctgttccagtggcccctgtgaaaatgggggcacctgccat
gcacaggagggcgaggatgccccgttcacgtgctcctgtcccaccggctttgaaggacca
acctgtggggtgaacacagatgactgtgtggatcatgcctgtgccaatgggggcgtctgt
gtggatggtgtgggcaactacacctgccagtgccccctgcagtatgagggaaaggcctgt
gagcagctggtggacttgtgctctccggatctgaacccatgtcaacacgaggcccagtgt
gtgggcaccccggatgggcccaggtgtgagtgcatgccaggttatgcaggtgacaactgc
agtgagaaccaggatgactgcagggaccaccgctgccagaatggggcccagtgtatggat
gaagtcaacagctactcctgcctctgtgctgagggctacagtggacagctctgtgagatc
cctccccatctgcctgcccccaagagcccctgtgaggggactgagtgccagaatggggcc
aactgtgtggaccagggcaacaggcctgtgtgccagtgcctcccaggcttcggtggccct
gagtgtgagaagttgctcagtgtcaactttgtggatcgggacacttacctgcagttcact
gacctgcaaaactggccacgggccaacatcacgttgcaggtctccacggcagaggacaat
gggatccttctgtacaacggggacaacgaccacattgcagttgagctgtaccagggccat
gtgcgtgtcagctacgacccaggcagctaccccagctctgccatctacagtgctgagacg
atcaacgatgggcaattccacaccgttgagctggttgcctttgaccagatggtgaatctc
tccattgatggcgggagccccatgaccatggacaactttggcaaacattacacgctcaac
agcgaggcgccactctatgtgggagggatgcccgtggatgtcaactcagctgccttccgc
ctgtggcagatcctcaacggcaccggcttccacggttgcatccgaaacctgtacatcaac
aacgagctgcaggacttcaccaagacgcagatgaagccaggcgtggtgccaggctgcgaa
ccctgccgcaagctctactgcctgcatggcatctgccagcccaatgccaccccagggccc
atgtgccactgcgaggctggctgggtgggcctgcactgtgaccagcccgctgacggcccc
tgccatggccacaagtgtgtccatgggcaatgcgtgcccctcgacgctctttcctacagc
tgccagtgccaggatgggtactcgggggcactgtgcaaccaggccggggccctggcagag
ccctgcagaggcctgcagtgcctgcatggccactgccaggcctcaggcaccaagggggca
cactgtgtgtgtgaccccggcttttcgggcgagctgtgtgagcaagagtccgagtgccgg
ggggaccctgtccgggactttcaccaggtccagaggggctatgccatctgccagaccacg
cgccccctgtcatgggtggagtgccggggctcgtgcccaggccagggctgctgccagggc
cttcggctgaagcggaggaagttcacctttgagtgcagcgatgggacctcttttgccgag
gaggtggaaaagcccaccaagtgtggctgtgccctctgcgcatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (14)   
   Pfam (14)   
All databases (71)   

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