KEGG   Homo sapiens (human): 6677
Entry
6677              CDS       T01001                                 
Symbol
SPAM1, HEL-S-96n, HYA1, HYAL1, HYAL3, HYAL5, PH-20, PH20, SPAG15
Name
(RefSeq) sperm adhesion molecule 1
  KO
K01197  hyaluronoglucosaminidase [EC:3.2.1.35]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00531  Glycosaminoglycan degradation
hsa01100  Metabolic pathways
hsa04142  Lysosome
Module
hsa_M00076  Dermatan sulfate degradation
hsa_M00077  Chondroitin sulfate degradation
Network
nt06012  Glycosaminoglycan degradation
  Element
N00610  Dermatan sulfate degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    6677 (SPAM1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    6677 (SPAM1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins [BR:hsa02042]
    6677 (SPAM1)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    6677 (SPAM1)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    6677 (SPAM1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.35  hyaluronoglucosaminidase
     6677 (SPAM1)
Bacterial toxins [BR:hsa02042]
 Toxins that damage the extracellular matrix
  Hyaluronidases/Collagenases
   6677 (SPAM1)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Enzymes
   6677 (SPAM1)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Enzymes
  6677 (SPAM1)
SSDB
Motif
Pfam: Glyco_hydro_56 DUF2180
Other DBs
NCBI-GeneID: 6677
NCBI-ProteinID: NP_001167515
OMIM: 600930
HGNC: 11217
Ensembl: ENSG00000106304
UniProt: P38567 Q5D1J4
Position
7:123925241..123971414
AA seq 509 aa
MGVLKFKHIFFRSFVKSSGVSQIVFTFLLIPCCLTLNFRAPPVIPNVPFLWAWNAPSEFC
LGKFDEPLDMSLFSFIGSPRINATGQGVTIFYVDRLGYYPYIDSITGVTVNGGIPQKISL
QDHLDKAKKDITFYMPVDNLGMAVIDWEEWRPTWARNWKPKDVYKNRSIELVQQQNVQLS
LTEATEKAKQEFEKAGKDFLVETIKLGKLLRPNHLWGYYLFPDCYNHHYKKPGYNGSCFN
VEIKRNDDLSWLWNESTALYPSIYLNTQQSPVAATLYVRNRVREAIRVSKIPDAKSPLPV
FAYTRIVFTDQVLKFLSQDELVYTFGETVALGASGIVIWGTLSIMRSMKSCLLLDNYMET
ILNPYIINVTLAAKMCSQVLCQEQGVCIRKNWNSSDYLHLNPDNFAIQLEKGGKFTVRGK
PTLEDLEQFSEKFYCSCYSTLSCKEKADVKDTDAVDVCIADGVCIDAFLKPPMETEEPQI
FYNASPSTLSATMFIVSILFLIISSVASL
NT seq 1530 nt   +upstreamnt  +downstreamnt
atgggagtgctaaaattcaagcacatctttttcagaagctttgttaaatcaagtggagta
tcccagatagttttcaccttccttctgattccatgttgcttgactctgaatttcagagca
cctcctgttattccaaatgtgcctttcctctgggcctggaatgccccaagtgaattttgt
cttggaaaatttgatgagccactagatatgagcctcttctctttcataggaagcccccga
ataaacgccaccgggcaaggtgttacaatattttatgttgatagacttggctactatcct
tacatagattcaatcacaggagtaactgtgaatggaggaatcccccagaagatttcctta
caagaccatctggacaaagctaagaaagacattacattttatatgccagtagacaatttg
ggaatggctgttattgactgggaagaatggagacccacttgggcaagaaactggaaacct
aaagatgtttacaagaataggtctattgaattggttcagcaacaaaatgtacaacttagt
ctcacagaggccactgagaaagcaaaacaagaatttgaaaaggcagggaaggatttcctg
gtagagactataaaattgggaaaattacttcggccaaatcacttgtggggttattatctt
tttccggattgttacaaccatcactataagaaacccggttacaatggaagttgcttcaat
gtagaaataaaaagaaatgatgatctcagctggttgtggaatgaaagcactgctctttac
ccatccatttatttgaacactcagcagtctcctgtagctgctacactctatgtgcgcaat
cgagttcgggaagccatcagagtttccaaaatacctgatgcaaaaagtccacttccggtt
tttgcatatacccgcatagtttttactgatcaagttttgaaattcctttctcaagatgaa
cttgtgtatacatttggcgaaactgttgctctgggtgcttctggaattgtaatatgggga
accctcagtataatgcgaagtatgaaatcttgcttgctcctagacaattacatggagact
atactgaatccttacataatcaacgtcacactagcagccaaaatgtgtagccaagtgctt
tgccaggagcaaggagtgtgtataaggaaaaactggaattcaagtgactatcttcacctc
aacccagataattttgctattcaacttgagaaaggtggaaagttcacagtacgtggaaaa
ccgacacttgaagacctggagcaattttctgaaaaattttattgcagctgttatagcacc
ttgagttgtaaggagaaagctgatgtaaaagacactgatgctgttgatgtgtgtattgct
gatggtgtctgtatagatgcttttctaaaacctcccatggagacagaagaacctcaaatt
ttctacaatgcttcaccctccacactatctgccacaatgttcattgttagtattttgttt
cttatcatttcttctgtagcgagtttgtaa

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (29)   
   RefSeq(nuc) (5)   
   GenBank (12)   
   EMBL (12)   
Protein domain (2)   
   Pfam (2)   
All databases (77)   

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