KEGG   Homo sapiens (human): 7841
Entry
7841              CDS       T01001                                 
Symbol
MOGS, CDG2B, CWH41, DER7, GCS1
Name
(RefSeq) mannosyl-oligosaccharide glucosidase
  KO
K01228  mannosyl-oligosaccharide glucosidase [EC:3.2.1.106]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00510  N-Glycan biosynthesis
hsa01100  Metabolic pathways
hsa04141  Protein processing in endoplasmic reticulum
Module
hsa_M00073  N-glycan precursor trimming
Network
nt06015  N-Glycan biosynthesis
  Element
N00820  N-Glycan biosynthesis
Disease
H00119  Congenital disorders of glycosylation type II
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    7841 (MOGS)
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    7841 (MOGS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    7841 (MOGS)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.106  mannosyl-oligosaccharide glucosidase
     7841 (MOGS)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   7841 (MOGS)
SSDB
Motif
Pfam: Glyco_hydro_63 Glyco_hydro_63N
Other DBs
NCBI-GeneID: 7841
NCBI-ProteinID: NP_006293
OMIM: 601336
HGNC: 24862
Ensembl: ENSG00000115275
UniProt: Q13724 A0A384MDR6
Position
2:complement(74461057..74465382)
AA seq 837 aa
MARGERRRRAVPAEGVRTAERAARGGPGRRDGRGGGPRSTAGGVALAVVVLSLALGMSGR
WVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLM
WAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQH
GGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDF
RFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGL
PGSLKWEDRGPSGQGQGQFLIQQVTLKIPISIEFVFESGSAQAGGNQALPRLAGSLLTQA
LESHAEGFRERFEKTFQLKEKGLSSGEQVLGQAALSGLLGGIGYFYGQGLVLPDIGVEGS
EQKVDPALFPPVPLFTAVPSRSFFPRGFLWDEGFHQLVVQRWDPSLTREALGHWLGLLNA
DGWIGREQILGDEARARVPPEFLVQRAVHANPPTLLLPVAHMLEVGDPDDLAFLRKALPR
LHAWFSWLHQSQAGPLPLSYRWRGRDPALPTLLNPKTLPSGLDDYPRASHPSVTERHLDL
RCWVALGARVLTRLAEHLGEAEVAAELGPLAASLEAAESLDELHWAPELGVFADFGNHTK
AVQLKPRPPQGLVRVVGRPQPQLQYVDALGYVSLFPLLLRLLDPTSSRLGPLLDILADSR
HLWSPFGLRSLAASSSFYGQRNSEHDPPYWRGAVWLNVNYLALGALHHYGHLEGPHQARA
AKLHGELRANVVGNVWRQYQATGFLWEQYSDRDGRGMGCRPFHGWTSLVLLAMAEDY
NT seq 2514 nt   +upstreamnt  +downstreamnt
atggctcggggcgagcggcggcgccgcgcagtgccggcagagggagtgcggacagccgag
agggcggctcggggaggccccgggcgacgggacggccggggcggcgggccgcgtagcacg
gctggaggagtggctctggccgtcgtggtcctgtctttggccctgggtatgtcggggcgc
tgggtgctggcgtggtaccgtgcgcggcgggcggtcacgctgcactccgcgcctcctgtg
ttgcctgccgactcctccagccccgccgtggccccggacctcttctggggaacctaccgc
cctcacgtctacttcggcatgaagacccgcagcccgaagcccctcctcaccggactgatg
tgggcgcagcagggcaccaccccggggactcctaagctcaggcacacgtgtgagcagggg
gacggtgtgggtccctatggctgggagttccacgacggcctctccttcgggcgccaacac
atccaggatggggccttaaggctcaccactgagttcgtcaagaggcctgggggtcagcac
ggaggggactggagctggagagtgactgtagagcctcaggactcaggtacttctgccctc
cctttggtctccctgttcttctatgtggtgacagatggcaaggaagtcctactaccagag
gttggggccaaggggcagttgaagtttatcagtgggcacaccagtgaacttggtgacttc
cgctttacacttttgccaccaaccagtccaggggatacagcccccaagtatggcagctac
aatgtcttctggacctccaacccaggactgcccctgctgacagagatggtaaagagtcgc
ctaaatagctggtttcagcatcggcccccaggggccccccctgaacgctacctcggcttg
ccaggatccctgaagtgggaggacagaggtccaagtgggcaagggcaggggcagttcttg
atacagcaggtgaccctgaaaattcccatttccatagagtttgtgtttgaatcaggcagt
gcccaggcaggaggaaatcaagccctgccaagactggcaggcagtctactgacccaggcc
ctggagagccatgctgaaggctttagagagcgctttgagaagaccttccagctgaaggag
aagggcctgagctctggcgagcaggttttgggtcaggctgccctcagcggcctccttggt
ggaattggctacttctacggacaagggctggtattgccagacatcggggtggaagggtct
gagcagaaggtggacccagccctctttccacccgtacctctttttacagcagtgccctcc
cggtcattcttcccacgaggcttcctttgggatgaaggctttcaccagctggtggttcag
cggtgggatccctccctcacccgggaagcccttggccactggctggggctgctaaatgct
gatggctggattgggagggagcagatactgggggatgaggcccgagcccgggtgcctcca
gaattcctagtacaacgagcagtccacgccaaccccccaaccctacttttgcctgtagcc
catatgctagaggttggtgaccctgacgacttggctttcctccgaaaggccttgccccgc
ctgcatgcctggttttcctggctccatcagagccaggcaggcccactgccactatcttac
cgctggcggggacgggaccctgccttaccaaccttactgaaccccaagaccctaccctct
gggctggatgactacccccgggcttcacacccttcagtaaccgagcggcacctggacctg
cgatgttgggtggcactgggtgcccgtgtgctgacgcggctggcagagcatctgggtgag
gctgaggtagctgctgagctgggcccactggctgcctcactggaggcagcagagagcctg
gatgagctgcactgggccccagagctaggagtctttgcagactttgggaaccacacaaaa
gcagtacagctgaagcccaggccccctcaggggctcgttcgggtggtgggtcggccccaa
cctcaactgcagtatgtagatgctcttggctatgtcagtctttttcccttgctgctgcga
ctgctggaccccacctcatcccgccttgggcccctgctggacattctagccgacagccgc
catctctggagcccctttggtttacgctcccttgcagcctccagctccttttatggccag
cgcaattcagagcatgatcccccctactggcggggtgctgtgtggctcaatgtcaactac
ctggctttgggagcactccaccactatgggcatctggagggtcctcaccaggctcgggct
gccaaactccacggtgagctccgtgccaacgtggtaggcaatgtatggcgccagtaccag
gctacaggctttctttgggagcagtacagtgaccgcgatgggcgaggcatgggctgccgc
cctttccacggctggaccagccttgtcttactggccatggctgaagactactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (34)   
   RefSeq(nuc) (2)   
   GenBank (16)   
   EMBL (16)   
Protein domain (2)   
   Pfam (2)   
All databases (77)   

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