KEGG   Homo sapiens (human): 81631
Entry
81631             CDS       T01001                                 
Symbol
MAP1LC3B, ATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a
Name
(RefSeq) microtubule associated protein 1 light chain 3 beta
  KO
K10435  microtubule-associated protein 1 light chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04137  Mitophagy - animal
hsa04140  Autophagy - animal
hsa04216  Ferroptosis
hsa04371  Apelin signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa05014  Amyotrophic lateral sclerosis
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05131  Shigellosis
hsa05167  Kaposi sarcoma-associated herpesvirus infection
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06182  Shigella
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
nt06532  Autophagy
nt06536  Mitophagy
  Element
N00156  Autophagy-vesicle nucleation/elongation/maturation, LC3-II formation
N01137  PINK-Parkin-mediated autophagosome formation
N01139  Mutation-inactivated p62 to PINK-Parkin-mediated autophagosome formation
N01140  TBK1-mediated autophagosome formation
N01141  Mutation-inactivated TBK1 to TBK1-mediated autophagosome formation
N01716  Autophagy-vesicle nucleation/elongation/maturation, sequestosome-1-like receptor
N01721  Autophagosome and lysosome fusion, tethering factor
N01722  Autophagosome and lysosome fusion, tethering factor, GRASP55
N01756  PINK-Parkin-independent ubiquitin-mediated mitophagy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    81631 (MAP1LC3B)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    81631 (MAP1LC3B)
   04137 Mitophagy - animal
    81631 (MAP1LC3B)
  09143 Cell growth and death
   04216 Ferroptosis
    81631 (MAP1LC3B)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    81631 (MAP1LC3B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    81631 (MAP1LC3B)
  09171 Infectious disease: bacterial
   05131 Shigellosis
    81631 (MAP1LC3B)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    81631 (MAP1LC3B)
   05022 Pathways of neurodegeneration - multiple diseases
    81631 (MAP1LC3B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    81631 (MAP1LC3B)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    81631 (MAP1LC3B)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    81631 (MAP1LC3B)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    81631 (MAP1LC3B)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Other mitophagy factors
    81631 (MAP1LC3B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Microtubule-associated proteins (MAPs)
     81631 (MAP1LC3B)
SSDB
Motif
Pfam: ATG8 APG12 Rad60-SLD
Other DBs
NCBI-GeneID: 81631
NCBI-ProteinID: NP_073729
OMIM: 609604
HGNC: 13352
Ensembl: ENSG00000140941
UniProt: Q9GZQ8 Q658J6
Structure
Position
16:87392336..87404774
AA seq 125 aa
MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG
MKLSV
NT seq 378 nt   +upstreamnt  +downstreamnt
atgccgtcggagaagaccttcaagcagcgccgcaccttcgaacaaagagtagaagatgtc
cgacttattcgagagcagcatccaaccaaaatcccggtgataatagaacgatacaagggt
gagaagcagcttcctgttctggataaaacaaagttccttgtacctgaccatgtcaacatg
agtgagctcatcaagataattagaaggcgcttacagctcaatgctaatcaggccttcttc
ctgttggtgaacggacacagcatggtcagcgtctccacaccaatctcagaggtgtatgag
agtgagaaagatgaagatggattcctgtacatggtctatgcctcccaggagacgttcggg
atgaaattgtcagtgtaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (9)   
   KEGG PATHWAY (9)   
Network (15)   
   KEGG NETWORK (15)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (37)   
   RefSeq(nuc) (1)   
   GenBank (18)   
   EMBL (18)   
3D Structure (24)   
   PDB (24)   
Protein domain (3)   
   Pfam (3)   
All databases (122)   

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