KEGG   Homo sapiens (human): 8444
Entry
8444              CDS       T01001                                 
Symbol
DYRK3, DYRK5, RED, REDK, hYAK3-2
Name
(RefSeq) dual specificity tyrosine phosphorylation regulated kinase 3
  KO
K18669  dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    8444 (DYRK3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.1  dual-specificity kinase
     8444 (DYRK3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  DYRK family [OT]
   8444 (DYRK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH ABC1 Kdo RIO1 Choline_kinase YrbL-PhoP_reg TCAD9
Other DBs
NCBI-GeneID: 8444
NCBI-ProteinID: NP_003573
OMIM: 603497
HGNC: 3094
Ensembl: ENSG00000143479
UniProt: O43781
Structure
Position
1:206635536..206655158
AA seq 588 aa
MGGTARGPGRKDAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCPPCSNVLCNPSEPPPPR
RLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSPTVSQGKS
SDCLNTVKSNSSSKAPKVVPLTPEQALKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRHG
VIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQYVALKMV
RNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSIDLYELIK
KNKFQGFSVQLVRKFAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSSTKVIDFGSSC
FEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLAC
MMELLGMPPPKLLEQSKRAKYFINSKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPGS
KDWGTALKGCDDYLFIEFLKRCLHWDPSARLTPAQALRHPWISKSVPRPLTTIDKVSGKR
VVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLPKLIS
NT seq 1767 nt   +upstreamnt  +downstreamnt
atgggaggcacagctcgtgggcctgggcggaaggatgcggggccgcctggggccgggctc
ccgccccagcagcggaggttgggggatggtgtctatgacaccttcatgatgatagatgaa
accaaatgtcccccctgttcaaatgtactctgcaatccttctgaaccacctccacccaga
agactaaatatgaccactgagcagtttacaggagatcatactcagcactttttggatgga
ggtgagatgaaggtagaacagctgtttcaagaatttggcaacagaaaatccaatactatt
cagtcagatggcatcagtgactctgaaaaatgctctcctactgtttctcagggtaaaagt
tcagattgcttgaatacagtaaaatccaacagttcatccaaggcacccaaagtggtgcct
ctgactccagaacaagccctgaagcaatataaacaccacctcactgcctatgagaaactg
gaaataattaattatccagaaatttactttgtaggtccaaatgccaagaaaagacatgga
gttattggtggtcccaataatggagggtatgatgatgcagatggggcctatattcatgta
cctcgagaccatctagcttatcgatatgaggtgctgaaaattattggcaaggggagtttt
gggcaggtggccagggtctatgatcacaaacttcgacagtacgtggccctaaaaatggtg
cgcaatgagaagcgctttcatcgtcaagcagctgaggagatccggattttggagcatctt
aagaaacaggataaaactggtagtatgaacgttatccacatgctggaaagtttcacattc
cggaaccatgtttgcatggcctttgaattgctgagcatagacctttatgagctgattaaa
aaaaataagtttcagggttttagcgtccagttggtacgcaagtttgcccagtccatcttg
caatctttggatgccctccacaaaaataagattattcactgcgatctgaagccagaaaac
attctcctgaaacaccacgggcgcagttcaaccaaggtcattgactttgggtccagctgt
ttcgagtaccagaagctctacacatatatccagtctcggttctacagagctccagaaatc
atcttaggaagccgctacagcacaccaattgacatatggagttttggctgcatccttgca
gaacttttaacaggacagcctctcttccctggagaggatgaaggagaccagttggcctgc
atgatggagcttctagggatgccaccaccaaaacttctggagcaatccaaacgtgccaag
tactttattaattccaagggcataccccgctactgctctgtgactacccaggcagatggg
agggttgtgcttgtggggggtcgctcacgtaggggtaaaaagcggggtcccccaggcagc
aaagactgggggacagcactgaaagggtgtgatgactacttgtttatagagttcttgaaa
aggtgtcttcactgggacccctctgcccgcttgaccccagctcaagcattaagacaccct
tggattagcaagtctgtccccagacctctcaccaccatagacaaggtgtcagggaaacgg
gtagttaatcctgcaagtgctttccagggattgggttctaagctgcctccagttgttgga
atagccaataagcttaaagctaacttaatgtcagaaaccaatggtagtatacccctatgc
agtgtattgccaaaactgattagctag

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (31)   
   RefSeq(nuc) (9)   
   GenBank (11)   
   EMBL (11)   
3D Structure (1)   
   PDB (1)   
Protein domain (9)   
   Pfam (9)   
All databases (72)   

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