KEGG   Homo sapiens (human): 85446
Entry
85446             CDS       T01001                                 
Symbol
ZFHX2, MARSIS, ZFH-5, ZFH5, ZNF409
Name
(RefSeq) zinc finger homeobox 2
  KO
K09379  zinc finger homeobox protein 2
Organism
hsa  Homo sapiens (human)
Disease
H00774  Congenital insensitivity to pain
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    85446 (ZFHX2)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Homeo domain ZF
    85446 (ZFHX2)
SSDB
Motif
Pfam: Homeodomain Homeobox_KN zf-C2H2 zf-C2H2_2 zf-C2H2_jaz zf-met zf-H2C2_5 zf-C2H2_4 zf-Di19 Ada_Zn_binding
Other DBs
NCBI-GeneID: 85446
NCBI-ProteinID: NP_207646
OMIM: 617828
HGNC: 20152
Ensembl: ENSG00000136367
UniProt: Q9C0A1 A0A2P1H683 B9EK48 B7ZM83
Position
14:complement(23520857..23555952)
AA seq 2572 aa
MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL
LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG
EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG
FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL
LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP
SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA
KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR
LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN
SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ
AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML
HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA
QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR
CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD
KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA
RGAAHEENSQIYKFLLDMEGAEAGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQ
RRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPGKAPVTPLAEPPTPEKDAQNKTEQLAS
EETENKTGPSRDSANQTTVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVG
RPALHFHLSHLHNVVPECVEKLLLVATTVEMTFTTKVLSAPTLSPLDNGQEPPTHGPEPT
PSRDQAAEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDV
APPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPARPYKCTVCKESF
TQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQS
STLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFISGL
PFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL
AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAA
KALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEE
HVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEAG
GTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETSAYP
KDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFS
CVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPD
GEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSA
PPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRL
RTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRST
PGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPF
LPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAE
PESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGE
EIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVS
CRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTL
PRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQR
PMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPAL
LGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNAL
LQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTHRYLCRQCKMAF
DGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSGREALASHLRSSAHR
RKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTSTLLAL
NT seq 7719 nt   +upstreamnt  +downstreamnt
atggccacccttaactcagcctctaccactggtaccaccccctcccctgggcacaatgcc
ccgtccctgccttcggacaccttctcctccagcaccccctctgatcctgtcaccaaagat
ccccctgctgcctcctccacctctgagaacatgaggtcctcagagccagggggacagctc
ctggagtcgggctgtggcctcgtcccaccaaaggagattggggagccccaggaagggcct
gactgtggtcacttcccaccaaatgacccaggggtggaaaaggacaaggagcaggaggag
gaagaagaagggctccctcccatggacctaagcaaccacttattcttcacagctggaggt
gaggcctacctagtggccaagctgtccctgccaggtggcagtgaactcctgttaccaaag
ggcttcccctggggtgaggcgggcatcaaggaagagcccagtctgcccttccttgcctac
ccacccccctcacacctcactgcccttcacatccaacatggctttgacccaatccaaggc
tttagctcttctgaccaaattctgtcccatgatacctcagcaccatctccggctgcctgt
gaggaaaggcatggagctttctggagctaccagctggctccaaatccacccggagatccc
aaagatggccccatggggaacagcgggggcaaccacgtggcggtcttctggctctgcctt
ctgtgccgcctgggtttcagcaagccccaggcctttatggatcacacacagtctcatggg
gtgaagctaacccctgcccaatatcagggcctgtcaggtagcccagctgtactccaggag
ggagatgaaggctgcaaggccctcataagctttctggagccaaaactccctgctcgcccc
tcttctgacataccccttgacaacagcagcacagtgaacatggaggcgaatgtggcccag
acagaggatggcccccctgaggcagaagtccaggcccttatcctcctggatgaagaagtt
atggccctcagcccaccctctccacccacagccacctgggaccccagcccaacccaagcc
aaagaatcgccagtagcagcaggcgaggcagggccagattggttccctgaggggcaagaa
gaggatggagggctctgccccccactcaaccaaagctcacccacctccaaggaggggggc
actctccctgccccagtgggctcccccgaagaccccagtgacccaccccagccctatcgc
ctagctgatgactacaccccagcccctgcagccttccagggcctcagcctgtccagccac
atgtccctgctccactcacgcaactcctgcaagacactcaagtgtcccaagtgcaactgg
cactacaagtaccagcagaccctggatgtgcacatgcgagagaagcaccctgagagcaac
agtcactgcagctactgcagtgctgggggcgcccacccccgccttgctcgtggagagagc
tacaactgtggctacaaaccctaccgctgtgacgtctgcaactactctacaaccaccaaa
ggcaacctcagcatccatatgcagtctgacaagcacctggccaacctacagggcttccag
gcgggccctggtgggcagggaagtccaccagaggcatcactcccaccctccgcgggagac
aaagagcctaagaccaaatcatcctggcagtgcaaggtgtgcagctacgagacaaacatc
tcccgtaacctgcgcatccatatgacctctgagaagcacatgcagaatgtcctaatgctg
caccaggggctgccgctgggcctgccacctggattgatggggccaggccctcctccccca
ccaggggctacccccactagcccccctgaactcttccagtactttgggccccaggcccta
gggcagcctcagactcccttggctggcccggggctgaggccagacaagcccctggaagcc
cagctacttctcaatggtttccaccacgtaggagcacctgcccgcaagttccccacatcc
gcccctggaagcctatcccctgatgcccacctgcctccaagtcagctcctgggttcctca
tctgacagcctgcccacctcaccacccccagacgacagcctgtccctgaaggtgttccgc
tgcctagtgtgccaggccttcagcacagacagcctggagctgctgctctaccactgcagc
ataggccggagcctcccggaagctgaatggaaggaggtggctggtgacacccaccgctgc
aagctttgctgctatggcacccagctcaaggccaacttccaactccacctcaagactgac
aaacatgctcagaagtaccagctggcagcccacctgcgggaggggggtggagccatgggc
accccttccccagcatccctgggagatggggctccttatgggtctgtctccccactacac
ctgcgctgcaacatctgtgactttgagtccaacagcaaggagaagatgcagctgcatgcc
aggggtgcagcccacgaagaaaacagccaaatctataagtttctgctggacatggaggga
gcggaggcaggggcagagctggggctataccactgcctgttgtgtgcgtgggagacaccc
tcccgcttggctgtgctgcaacacctgcgcacacctgcccaccgcgatgcccaggcccag
aggcgtctgcagctgctacagaatggcccaaccactgaggaaggactcgcagctcttcag
agcatcctgagcttcagccacgggcagctccggactcccgggaaggctcctgtcaccccc
ttagctgagccacccacccctgagaaagatgcccagaacaagacagaacaattggcttca
gaagagacagaaaacaagactggcccttccagagacagtgccaaccagaccacggtatac
tgctgtccatactgcagcttcctgagcccagagtccagccaggtgagggctcatacactc
tcccagcatgcagtgcagcccaagtacagatgcccactgtgccaggaacagctggtgggc
cggcctgccctgcacttccaccttagccaccttcacaacgtggtgcccgagtgcgttgag
aagctgctgcttgtagctacaactgtagaaatgacatttacaaccaaagtgctgtctgca
cccacattaagccctctggacaatggccaagaaccccccactcatgggccagagcctaca
ccgagcagagaccaggcagcagaaggccctaacctgaccccagaagccagtccagatcct
cttcctgagcctcccctggcctcagttgaggtcccagacaaaccctcaggaagccctggc
caacccccttctccagccccatctccagtccctgaacctgatgcccaagctgaagacgta
gctcctccgcccaccatggctgaggaggaagaggggaccactggggagctccgctctgca
gagccagctccagctgactctcgccaccctctgacctatcggaaaaccaccaactttgcc
ctggacaagtttctcgaccctgcccggccctataagtgcactgtgtgtaaggagtccttc
acccagaagaatattctgttggttcattataattctgtctcccaccttcacaagatgaag
aaggctgccattgacccctctgcccctgcacggggagaggccggtgccccacccaccacc
actgctgccacagacaagccctttaagtgcacagtctgcagagtctcctacaaccagagc
tccaccctggagatccacatgcggtcagttctgcatcagactcgctctcggggaaccaag
actgattccaagattgaagggccagaacgcagccaagaagagcccaaggaaggcgagaca
gagggggaggtgggcactgagaagaagggccctgacaccagtggcttcatatctggattg
cctttcctgtcccctcccccacctcccttggacctgcaccgattcccagcccctctcttc
accccaccagtcctgccccccttccctctggtgcccgaatcactgcttaagctccagcag
cagcagctgctcctgcccttctacctccacgatctcaaggtggggcccaagctgacacta
gctgggcctgcacctgtgctgtccctgccagctgccacccctcctcctccaccccaacct
cccaaggctgagctggctgagcgggagtgggagcggccccccatggccaaagagggtaat
gaggcagggccttcctcaccccccgacccattgcccaacgaggctgcccgcactgcagcc
aaagcccttctagaaaactttggctttgagctggtgatccagtacaatgaagggaagcaa
gctgtgccccctccccctaccccacccccacctgaggccctcgggggtggggacaagctg
gcctgtggggcctgtgggaaactcttctccaatatgcttatcctcaagacacacgaggaa
catgtccaccgccgctttctgccctttgaagccctgagccgttatgctgctcagtttcga
aagagctatgacagcctatacccgccccttgcagagcctcccaaacctcctgatgggtct
ctggattcacctgttccccatctgggcccacccttcctggtcccagagcctgaggcaggg
gggacccgtgcccctgaagagcgaagtcgagcagggggacactggcccatagaagaggaa
gaaagctccagagggaatcttcctcccctggtgcctgccggccgccggttctccagaacc
aagttcacagagttccagacccaagccctgcagtctttctttgagactagcgcctacccc
aaagacggagaggtggagcgactcgcaagtctgttgggtctggctagccgtgtggtggtg
gtgtggttccagaatgcccgccagaaagcacgcaaaaatgcctgtgagggtgggtccatg
ccaaccggaggaggcactgggggagcctccggctgcaggcgttgccacgccactttctcc
tgtgtttttgagttggtgcgccacctcaagaagtgctatgatgaccagacccttgaagag
gaggaggaagaggcagagagaggggaagaggaggaagaggtggaagaagaagaagtagag
gaggaacagggccttgaacctccagcagggcctgagggcccattaccagagcctccagat
ggggaggagctgagccaagcagaggcaacaaaggcaggaggcaaagagcctgaagagaag
gctactccatcaccttccccagcccatacctgtgaccagtgtgccatttctttctccagc
caggacctcctgaccagtcaccgccgactacatttcctgccatctctgcagcccagtgct
cccccccaactcctagatctgcccttgctggtgtttggggagagaaaccccctggtggca
gccacctcaccaatgccaggtccacctctcaaacggaagcatgaggacggcagcttgtct
cccacaggcagtgaagcagggggaggaggggagggcgagccccccagggacaagcgcctg
cgcaccaccatcttgcctgagcagctagagatcctgtaccgttggtacatgcaggattcc
aacccaacacgcaagatgctcgactgcatctccgaggaggtggggctcaaaaagcgagtg
gtacaggtctggttccagaataccagggcccgggagaggaaaggccagtttcgaagcacc
cctgggggggtgcctagtccagcagtgaaaccgcctgccacagccacccctgcatccttg
cccaagttcaacctcttattaggcaaggtagatgatggcactgggagggaagccccaaag
agggaagcacctgcttttccctaccccactgccacgcttgcttctgggccccagcctttc
ctaccacctgggaaagaggccaccaccccaacaccagagccacctctacctctcctacct
ccccctccacccagtgaggaagagggcccagaggaaccacctaaagcttctccagagagt
gaggcttgcagtctctctgcaggagatctgagtgattcatctgcttccagcctagctgaa
ccagaatcccctggggctggagggaccagtgggggacctggaggtgggactggggttcca
gatggaatggggcagcggcgctacaggacccagatgagcagcctgcagctgaagatcatg
aaagcctgctatgaagcttaccgcacccccaccatgcaggagtgtgaggtgctgggagag
gagattgggctgcccaagagagtcatccaggtctggttccagaatgctcgtgccaaggaa
aagaaggccaaactacaggggacagccgctgggagcactgggggcagcagtgagggcctc
ttagcagcccagcgcactgactgcccctattgtgatgtcaagtatgatttctatgtctcc
tgccgaggccatctcttttcccgtcagcacctggccaagctcaaggaggcggttcgagcc
cagctgaagagtgaaagcaagtgctacgacttggccccagcacctgaggctcccccagct
ctcaaggccccacctgccaccacacctgcctccatgcccctcggggctgccccaaccttg
cctcgcctggcgccggtcctcttatctggcccagctctggctcagcccccgctgggcaac
ttagctcctttcaattcaggcccggcagcctcctcaggcctcctcggcctcgccacttcg
gtcctgcctaccaccacagtggtccagactgctggcccaggccgccccttacctcagaga
cccatgcccgaccaaaccaacacctccacagcaggcaccactgaccctgtcccaggccct
cctactgagcccttgggggacaaggtctccagtgagcgaaagccagttgcaggccccacc
agctcctccaatgatgccctcaagaacctcaaagcattgaagaccactgtcccagccctg
ttggggggccagttcctgccctttccattgccccctgctgggggaacagcaccgccagct
gtctttggcccccagctacagggggcctacttccaacagctctatggcatgaagaagggg
ctatttcccatgaaccccatgatacctcagaccctcattgggctgctccccaatgccctc
ctccagccgccaccccagccccctgagcccacagccacagcacctccaaagcctcctgaa
ctgcctgctccaggggagggggaagctggtgaggttgatgagctgctgacaggcagcact
ggcatctccaccgtggatgtaacccatcgctacctgtgccgccagtgcaagatggcattt
gacggggaggccccggctactgcccaccagagatccttctgcttctttgggcggggctct
gggggctccatgccacccccattgcgggtgcccatctgcacctaccactgcctggcatgt
gaggtgctgctgagtgggcgtgaagccctagcctcccacctgcgctcctcggcccacagg
cgcaaggcagccccacctcaagggggcccacccatctccatcaccaacgccgccactgct
gcctcggctgctgtggcttttgccaaagaggaagcaagattacctcacacggactccaac
ccaaaaactacgactacctctacacttctagctttataa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (62)   
   KEGG ORTHOLOGY (1)   
   RefGene (56)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (32)   
   UniProt (4)   
   SWISS-PROT (1)   
   RefSeq(pep) (27)   
DNA sequence (43)   
   RefSeq(nuc) (27)   
   GenBank (8)   
   EMBL (8)   
Protein domain (10)   
   Pfam (10)   
All databases (153)   

Download RDF
DBGET integrated database retrieval system