KEGG   Homo sapiens (human): 8672
Entry
8672              CDS       T01001                                 
Symbol
EIF4G3, eIF-4G_3, eIF4G_3, eIF4GII
Name
(RefSeq) eukaryotic translation initiation factor 4 gamma 3
  KO
K03260  translation initiation factor 4G
Organism
hsa  Homo sapiens (human)
Pathway
hsa05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09166 Cardiovascular disease
   05416 Viral myocarditis
    8672 (EIF4G3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    8672 (EIF4G3)
   03012 Translation factors [BR:hsa03012]
    8672 (EIF4G3)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    eIF4F and regulatory proteins
     8672 (EIF4G3)
   mRNA cycle factors
    Stress granule specific factors
     8672 (EIF4G3)
Translation factors [BR:hsa03012]
 Eukaryotic type
  Initiation factors
   eIF-4
    8672 (EIF4G3)
SSDB
Motif
Pfam: MIF4G MA3 W2 eIF4G1-like_eIF4E-bd PP_kinase
Other DBs
NCBI-GeneID: 8672
NCBI-ProteinID: NP_003751
OMIM: 603929
HGNC: 3298
Ensembl: ENSG00000075151
UniProt: O43432 Q59GJ0
Structure
Position
1:complement(20806292..21176897)
AA seq 1585 aa
MNSQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPV
PQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQ
SAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTP
PQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLS
GEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDR
CELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEIN
GVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPT
PPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQ
TEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKV
LESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSS
GDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPK
LPMRTLDPRILPRGPDFTPAFADFGRQTPGGRGVPLLNVGSRRSQPGQRREPRKIITVSV
KEDVHLKKAENAWKPSQKRDSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGL
TVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNR
CQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELF
KLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIV
KERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK
EKRRPGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVPKAQLGSWGKGSS
GGAKASETDALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSRGSMGREKNDKP
LPSATARPNTFMRGGSSKDLLDNQSQEEQRREMLETVKQLTGGVDVERNSTEAERNKTRE
SAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEELNAQGLLHVFVR
VGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYL
AELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREAD
LSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKAN
DEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQRVPILLKYL
DSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNG
KGVALKSVTAFFTWLREAEEESEDN
NT seq 4758 nt   +upstreamnt  +downstreamnt
atgaattcacaacctcaaacccgttctccgtttttccagaggcctcaaatacagcctcct
agagctaccatcccgaacagcagtccttccattcgtcctggtgcacagacacccactgca
gtgtaccaggctaatcagcacatcatgatggttaaccatctgcccatgccgtacccagtg
ccccaggggcctcagtactgtataccacagtaccgtcatagtggccctccttatgttggg
cccccccaacaatatccagttcaaccaccggggccaggtcctttttatcctggaccagga
cctggggacttccccaatgcttatggaacgcctttttacccaagtcagccggtgtatcag
tcagcacctatcatagtgcctacgcagcaacagccgcctccagccaagagagagaaaaaa
actataagaattcgggatccaaaccagggaggtaaagacataacagaggagattatgtct
ggaggtggcagcagaaatcctactccacccataggaagacccacgtccacacctactcct
cctcagcagctgcccagccaggtccccgagcacagccctgtggtttatgggactgtggag
agcgctcatcttgctgccagcacccctgtcactgcagctagcgaccagaagcaagaggag
aagccaaaaccagatccagtgttaaagtctccttccccagtccttaggctagtcctcagt
ggagagaagaaagaacaagaaggccagacatctgaaactactgcaatagtatccatagca
gagcttcctctgcctccatcacctaccactgtttcttctgttgctcgaagtacaattgca
gcccccacctcttctgctcttagtagccaaccaatattcaccactgctatagatgacaga
tgtgaactctcatccccaagagaagacacaattcctatacccagcctcacatcttgcaca
gaaacatcagaccctttaccaacaaatgaaaatgatgatgatatatgcaagaaaccctgt
agtgtagcacctaatgatattccactggtttctagtactaacctaattaatgaaataaat
ggagttagcgaaaaattatcagccacggagagcattgtggaaatagtaaaacaggaagta
ttgccattgactcttgaattggagattctcgaaaatcccccagaagaaatgaaactggag
tgtatcccagctcccatcaccccttccacagttccttcctttcctccaactcctccaact
cctccagcttctcctcctcacactccagtcattgttcctgctgctgccactactgttagt
tctccgagtgctgccatcacagtccagagagtcctagaggaggacgagagcataagaact
tgccttagtgaagatgcaaaagagattcagaacaaaatagaggtagaagcagatgggcaa
acagaagagattttggattctcaaaacttaaattcaagaaggagccctgtcccagctcaa
atagctataactgtaccaaagacatggaagaaaccaaaagatcggacccgaaccactgaa
gagatgttagaggcagaattggagcttaaagctgaagaggagctttccattgacaaagta
cttgaatctgaacaagataaaatgagccaggggtttcatcctgaaagagacccctctgac
ctaaaaaaagtgaaagctgtggaagaaaatggagaagaagctgagccagtacgtaatggt
gctgagagtgtttctgagggtgaaggaatagatgctaattcaggctccacagatagttct
ggtgatggggttacatttccatttaaaccagaatcctggaagcctactgatactgaaggt
aagaagcagtatgacagggagtttctgctggacttccagttcatgcctgcctgtatacaa
aaaccagagggcctgcctcctatcagtgatgtggttcttgacaagatcaaccaacccaaa
ttgccaatgcgaactctggatcctcgaattttgcctcgaggaccagactttacaccagcc
tttgctgattttggaaggcagacacctggtggaagaggcgtacctttgttgaatgttggg
tcacgaagatctcaacctggccaaagaagagaacccagaaagatcatcacagtttctgta
aaagaagatgtacacctgaaaaaggcagaaaatgcctggaagccaagccaaaaacgagac
agccaagccgatgatcccgaaaacattaaaacccaggagctttttagaaaagttcgaagt
atcttaaataaattgacaccacagatgttcaatcaactgatgaagcaagtgtcaggactt
actgttgacacagaggagcggctgaaaggagttattgacctggtctttgagaaggctatt
gatgaacccagtttctctgtggcttacgcaaacatgtgtcgatgtctagtaacgctgaaa
gtacccatggcagacaagcctggtaacacagtgaatttccggaagctgctactgaaccgt
tgccagaaggagtttgaaaaagataaagcagatgatgatgtctttgagaagaagcagaaa
gaacttgaggctgccagtgctccagaggagaggacaaggcttcatgatgaactggaagaa
gccaaggacaaagcccggcggagatccattggcaacatcaagtttattggagaactcttt
aaactcaaaatgctgactgaagccatcatgcatgactgtgtggtgaagctgctaaagaac
catgatgaagaatccctggagtgcctgtgtcgcctgctcaccaccattggcaaagacttg
gactttgaaaaagcaaagccacgtatggaccagtactttaatcagatggagaaaattgtg
aaagaaagaaaaacctcatctaggattcggttcatgcttcaagatgttatagacctaagg
ctgtgcaattgggtatctcgaagagcagatcaagggcctaaaactatcgaacagattcac
aaagaggctaaaatagaagaacaagaagagcaaaggaaggtccagcaactcatgaccaaa
gagaagagaagaccaggtgtccagagagtggacgaaggtgggtggaacactgtacaaggg
gccaagaacagtcgggtactggacccctcaaaattcctaaaaatcactaagcctacaatt
gatgaaaaaattcagctggtacctaaagcacagctaggcagctggggaaaaggcagcagt
ggtggagcaaaggcaagtgagactgatgccttacggtcaagtgcttccagtttaaacaga
ttctctgccctgcaacctccagcaccctcagggtccacgccatccacgcctgtagagttt
gattcccgaaggaccttaactagtcgtggaagtatgggcagggagaagaatgacaagccc
cttccatctgcaacagctcggccaaatactttcatgaggggtggcagcagtaaagacctg
ctagacaatcagtctcaagaagagcagcggagagagatgctggagaccgtgaagcagctc
acaggaggtgtggatgtggagaggaacagcactgaggctgagcgaaataaaacaagggag
tcagcaaaaccagaaatttcagcaatgtcagctcatgacaaggctgcattatcagaagag
gaactggagaggaagtcgaaatctatcattgatgaatttctacacattaatgattttaag
gaagccatgcagtgtgtggaagagctgaatgcccagggcctactacatgtttttgtgaga
gtgggagtggagtccaccctggaaaggagccagatcaccagggatcacatgggccaatta
ctctatcagctggtacagtcagaaaaactcagcaaacaggactttttcaaaggtttttca
gaaactttggaattggcagatgacatggccattgatattccccatatttggttgtacctt
gctgaactggtgacccccatgttaaaagaaggtggaatctccatgagagaacttaccata
gaatttagcaaacctttacttcctgttggaagagctggggtcttgctatctgaaatattg
cacctactatgcaaacaaatgagccataagaaagtgggagccttatggagggaggctgac
ctcagctggaaggactttttaccagaaggagaagatgtacataattttcttttggagcag
aagttggacttcatagagtctgacagtccctgttcctctgaagcactttcaaagaaagaa
ctgtctgccgaagagctgtataagcgactcgagaaactcattattgaggacaaagcgaat
gatgaacagatctttgactgggtagaggctaatctagacgaaatccagatgagttcacct
acattccttagagctttaatgactgctgtttgtaaagcagctattatagccgactcttct
accttcagagtggacactgctgttatcaagcagagagtgccgatcttactcaagtaccta
gactcagatacagagaaggaactgcaagcactttatgcactacaagcatcgatagtaaaa
cttgatcaacctgccaatttgctgcggatgttttttgattgtctatatgacgaggaggtg
atctccgaggatgccttctacaaatgggagagcagcaaggaccctgcagagcagaatggg
aagggcgtggctctgaaatctgtcacggcattcttcacgtggctgcgggaagcagaagag
gagtctgaggataactaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (109)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (106)   
DNA sequence (142)   
   RefSeq(nuc) (106)   
   GenBank (18)   
   EMBL (18)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (287)   

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