KEGG   Homo sapiens (human): 8731
Entry
8731              CDS       T01001                                 
Symbol
RNMT, CMT1, CMT1c, MET, N7-MTase, RG7MT1, cm1p, hCMT1, hMet
Name
(RefSeq) RNA guanine-7 methyltransferase
  KO
K00565  mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    8731 (RNMT)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    8731 (RNMT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.56  mRNA (guanine-N7)-methyltransferase
     8731 (RNMT)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA processing factors
   5' end processing
    Capping factors
     8731 (RNMT)
SSDB
Motif
Pfam: mRNA_G-N7_MeTrfase Methyltransf_31 Methyltransf_11 Methyltransf_25 Methyltransf_12 Methyltransf_23 SH3BGR Methyltransf_32 FtsJ MTS
Other DBs
NCBI-GeneID: 8731
NCBI-ProteinID: NP_003790
OMIM: 603514
HGNC: 10075
Ensembl: ENSG00000101654
UniProt: O43148
Structure
Position
18:13726673..13764556
AA seq 476 aa
MANSAKAEEYEKMSLEQAKASVNSETESSFNINENTTASGTGLSEKTSVCRQVDIARKRK
EFEDDLVKESSSCGKDTPSKKRKLDPEIVPEEKDCGDAEGNSKKRKRETEDVPKDKSSTG
DGTQNKRKIALEDVPEKQKNLEEGHSSTVAAHYNELQEVGLEKRSQSRIFYLRNFNNWMK
SVLIGEFLEKVRQKKKRDITVLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQRY
EDMKNRRDSEYIFSAEFITADSSKELLIDKFRDPQMCFDICSCQFVCHYSFESYEQADMM
LRNACERLSPGGYFIGTTPNSFELIRRLEASETESFGNEIYTVKFQKKGDYPLFGCKYDF
NLEGVVDVPEFLVYFPLLNEMAKKYNMKLVYKKTFLEFYEEKIKNNENKMLLKRMQALEP
YPANESSKLVSEKVDDYEHAAKYMKNSQVRLPLGTLSKSEWEATSIYLVFAFEKQQ
NT seq 1431 nt   +upstreamnt  +downstreamnt
atggcaaattctgcaaaagcagaagaatatgaaaagatgtctcttgaacaggcaaaagcg
tcagtgaattctgaaacagagtcttcattcaatattaatgaaaacacaacagcttctggg
actgggctttctgaaaagacttctgtctgtaggcaagtagacatagcaagaaagagaaaa
gagtttgaagatgatcttgtaaaggaaagttctagttgtgggaaagacactccatccaag
aagagaaaacttgatcctgaaattgtcccagaggaaaaagattgtggtgatgctgaaggc
aattcaaagaaaagaaaaagagaaactgaggatgttccaaaagataaatcttctactgga
gatggcactcaaaataagagaaaaatagcacttgaggatgttcctgaaaagcagaaaaat
ctggaagaaggacacagctcaacagtggctgcccattacaatgaacttcaggaagttggt
ttggagaagcgtagtcaaagtcgtattttttacctaagaaactttaataattggatgaaa
agtgttctcattggagaatttttggaaaaggtacgacagaagaaaaaacgtgatatcact
gttttggacctgggatgtggtaaaggtggagatttgctgaaatggaaaaaaggaagaatt
aacaagctagtttgtactgatattgccgatgtttctgtcaaacagtgtcagcagcggtat
gaggacatgaaaaatcgtcgtgatagtgaatatattttcagtgcagaatttataactgct
gacagctcaaaggaacttctgattgacaaatttcgtgacccacaaatgtgttttgacatc
tgcagttgtcagtttgtctgtcattactcatttgagtcttatgagcaggctgacatgatg
ctgagaaatgcgtgtgagagacttagccctgggggctattttattggtactactcccaat
agctttgaattgataagacgccttgaagcttcagaaacagaatcatttggaaatgaaata
tatactgtgaaatttcagaagaaaggagattatcctttatttggctgcaaatatgacttc
aacttggaaggtgttgtggatgttcctgaattcttggtctattttccattgctaaatgaa
atggcaaagaagtacaatatgaaactagtctacaaaaaaacatttctggaattctacgaa
gaaaagattaagaacaatgaaaataaaatgctcttaaaacgaatgcaggccttggagcca
tatcctgcaaatgagagttctaaacttgtctctgagaaggtggatgactatgaacatgca
gcaaagtacatgaagaacagtcaagtaaggttacctttgggaaccttaagtaaatcagaa
tgggaagctacaagtatttacttggtgtttgcctttgagaaacagcagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (19)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (17)   
DNA sequence (46)   
   RefSeq(nuc) (18)   
   GenBank (14)   
   EMBL (14)   
3D Structure (5)   
   PDB (5)   
Protein domain (10)   
   Pfam (10)   
All databases (110)   

Download RDF
DBGET integrated database retrieval system