KEGG   Homo sapiens (human): 8803
Entry
8803              CDS       T01001                                 
Symbol
SUCLA2, A-BETA, A-SCS, LINC00444, MTDPS5, SCS-betaA
Name
(RefSeq) succinate-CoA ligase ADP-forming subunit beta
  KO
K01900  succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00020  Citrate cycle (TCA cycle)
hsa00640  Propanoate metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
Module
hsa_M00009  Citrate cycle (TCA cycle, Krebs cycle)
hsa_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Network
nt06031  Citrate cycle and pyruvate metabolism
  Element
N01617  Citrate cycle, second carbon oxidation 2
Disease
H00469  Mitochondrial DNA depletion syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    8803 (SUCLA2)
   00640 Propanoate metabolism
    8803 (SUCLA2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    8803 (SUCLA2)
Enzymes [BR:hsa01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.4  succinate---CoA ligase (GDP-forming)
     8803 (SUCLA2)
    6.2.1.5  succinate---CoA ligase (ADP-forming)
     8803 (SUCLA2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   8803 (SUCLA2)
SSDB
Motif
Pfam: ATP-grasp_2 Ligase_CoA ATP-grasp_5 CPSase_L_D2 GARS_A
Other DBs
NCBI-GeneID: 8803
NCBI-ProteinID: NP_003841
OMIM: 603921
HGNC: 11448
Ensembl: ENSG00000136143
UniProt: Q9P2R7 E5KS60 Q9Y4T0
Structure
Position
13:complement(47942656..48001273)
AA seq 463 aa
MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS
MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK
IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP
VLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM
VKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER
DKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEA
FKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALI
ADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
NT seq 1392 nt   +upstreamnt  +downstreamnt
atggcggcctccatgttctacggcaggctagtggccgtggccacccttcggaaccaccgg
cctcggacggcccagcgggctgctgctcaggttctgggaagttctggattgtttaataac
catggactccaagtacagcagcaacagcaaaggaatctctcactacatgaatacatgagt
atggaattattgcaagaagctggtgtctccgttcccaaaggatatgtggcaaagtcacca
gatgaagcttatgcaattgccaaaaaattaggttcaaaagatgtcgtgataaaggcacag
gttttagctggtggtagaggaaaaggaacatttgaaagtggcctcaaaggaggagtgaag
atagttttctctccagaagaagcaaaagctgtttcttcacaaatgattgggaaaaaattg
tttaccaagcaaacgggagaaaagggcagaatatgcaatcaagtattggtctgtgagcga
aaatatcccaggagagaatactactttgcaataacaatggaaaggtcatttcaaggtcct
gtattaataggaagttcacatggtggtgtcaacattgaagatgttgctgctgagtctcct
gaagcaataattaaagaacctattgatattgaagaaggcatcaaaaaggaacaagctctc
cagcttgcacagaagatgggatttccacctaatattgtggaatcagcagcagaaaacatg
gtcaagctttacagcctttttctgaaatacgatgcaaccatgatagaaataaatccaatg
gtggaagattcagatggagctgtattgtgtatggatgcaaagatcaattttgactctaat
tcagcctatcgccaaaagaaaatctttgatctacaggactggacccaggaagatgaaagg
gacaaagatgctgctaaggcaaatctcaactacattggcctcgatggaaatataggctgc
ctagtaaatggtgctggtttggctatggccacaatggatataataaaacttcatggaggg
actccagccaacttccttgatgttggtggtggtgctacagtccatcaagtaacagaagca
tttaagcttatcacttcagataaaaaggtactggctattctggtcaacatttttggagga
atcatgcgctgtgatgttattgcacagggtatagtcatggcagtaaaagacttggaaatt
aaaatacctgttgtggtacggttacaaggtacacgagtcgatgatgctaaggcactgata
gcggacagtggacttaaaatacttgcttgtgatgacttggatgaagctgctagaatggtt
gtaaagctctctgaaatagtgaccttagcgaagcaagcacatgtggatgtgaaatttcag
ttgccaatatga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (5)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (35)   
   RefSeq(nuc) (1)   
   GenBank (17)   
   EMBL (17)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (85)   

Download RDF
DBGET integrated database retrieval system