KEGG T01001: 9836

Homo sapiens (human): 9836

Entry

9836              CDS       T01001

Symbol

LCMT2, PPM2, TYW4

Name

(RefSeq) leucine carboxyl methyltransferase 2

K15451

tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]

Organism

hsa Homo sapiens (human)

Brite

KEGG Orthology (KO) [BR:hsa00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:hsa03016]
    9836 (LCMT2)
Enzymes [BR:hsa01000]
2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.290  tRNAPhe [7-(3-amino-3-carboxypropyl)wyosine37-O]-methyltransferase
     9836 (LCMT2)
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.231  tRNAPhe {7-[3-amino-3-(methoxycarbonyl)propyl]wyosine37-N}-methoxycarbonyltransferase
     9836 (LCMT2)
Transfer RNA biogenesis [BR:hsa03016]
Eukaryotic type
  tRNA modification factors
   Methyltransferases
    9836 (LCMT2)

SSDB

Motif

Pfam:

LCM Kelch_6 Kelch_5 Kelch_3 Kelch_2 Kelch_1

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Position

15:complement(43323649..43330573)

AA seq 686 aa
MGPRSRERRAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYVRA
RAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWEVDFPDVAR
RKAERIGETPELCALTGPFERGEPASALCFESADYCILGLDLRQLQRVEEALGAAGLDAA
SPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNS
PLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWH
LKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPASVVSSEGQVPNLKRYGH
ASVFLSPDVILSAGGFGEQEGRHCRVSQFHLLSRDCDSEWKGSQIGSCGTGVQWDGRLYH
TMTRLSESRVLVLGGRLSPVSPALGVLQLHFFKSEDNNTEDLKVTITKAGRKDDSTLCCW
RHSTTEVSCQNQEYLFVYGGRSVVEPVLSDWHFLHVGTMAWVRIPVEGEVPEARHSHSAC
TWQGGALIAGGLGASEEPLNSVLFLRPISCGFLWESVDIQPPITPRYSHTAHVLNGKLLL
VGGIWIHSSSFPGVTVINLTTGLSSEYQIDTTYVPWPLMLHNHTSILLPEEQQLLLLGGG
GNCFSFGTYFNPHTVTLDLSSLSAGQ

NT seq 2061 nt +upstreamnt +downstreamnt
atgggcccccggagccgtgagcgtcgggcaggcgcggtacagaacaccaacgacagcagc
gccctcagcaagcgttccctggccgcgcgcgggtacgtgcaggacccctttgccgcgttg
ctggttccgggcgcggcgcgccgcgcaccgctcattcaccgaggctactacgtccgcgca
cgcgccgtgaggcactgcgtgcgcgcttttttggagcagattggcgcgccccaggccgcg
cttcgcgcgcagatcttgtctctcggcgctggcttcgactcgctctattttcgcttaaaa
accgcgggccgcctggcccgggctgcagtctgggaggtggattttccggacgtggcgcgg
cgcaaagcagaaaggattggagagacgccagagctgtgcgcgttaaccgggcctttcgag
aggggggagcccgcgtccgcgctgtgctttgagagcgcagactactgcatcctgggtctg
gacttgcggcagctccagcgagtggaggaggccctgggcgccgcggggctcgacgcagcc
tcacccactctgctcctggccgaggcggtgctgacctacctcgagccggagagtgccgcg
gccctcatcgcctgggcagcccagcgttttcctaatgcccttttcgtggtctatgagcag
atgaggcctcaagacgcctttggccagttcatgctgcaacattttcggcagctaaactcc
cccctgcatggcctggagcgttttcctgacgtggaggcgcagcggcgccgcttccttcaa
gctggctggaccgcctgcggtgccgtggacatgaatgaattctatcactgctttcttccc
gcagaagaacgccggcgggtggaaaatattgaaccctttgacgaatttgaggagtggcat
ctgaagtgcgcccattatttcattctggcagcttctaggggagacaccctctcccacacc
ctagtgtttccatcctcagaggcatttcctcgcgtaaatcctgcttcgccttcaggggta
ttccctgccagcgtagtcagtagcgagggccaggtcccaaacctgaagagatatggccac
gcctctgtcttcttgagcccagacgttattctcagtgcaggaggatttggagagcaggag
gggcggcactgccgagtgagccagtttcacttgctctcaagagattgtgactctgaatgg
aaaggcagccaaataggcagttgtgggactggagttcagtgggatggacgcctttatcac
accatgacaagactctcagagagtcgggttctggttctgggagggagactgtccccagta
agtccagccttgggggttctccagcttcatttttttaagagtgaggataataacactgag
gacctgaaagtgacaataacaaaggctggccgaaaggatgattccactttgtgttgttgg
cggcattcaacaacagaagtgtcctgtcagaatcaggaatatttgtttgtgtatgggggt
cgaagcgtggtggaacctgtactaagtgactggcatttcctccatgtagggacaatggct
tgggtcaggatcccagtggagggagaagtacctgaagcccggcattctcacagtgcctgc
acttggcaagggggagcccttattgctggaggtctcggggcttctgaggagccattgaac
tctgtgctctttctgagaccaatctcttgtggattcctctgggagtcagtagacatccag
cctcccattaccccaaggtactcccacacagctcatgtgctcaatggaaagctgttactg
gttggagggatctggattcattcctcctcatttcctggagtgactgtgatcaatttgact
acaggattgagctctgagtatcagattgacacaacatatgtgccatggccattaatgtta
cacaaccatactagtatccttcttcctgaagagcaacagctcctgctccttggaggtggt
gggaactgcttttcctttggtacctacttcaacccccatacagtcacattagacctttct
tccttaagtgctgggcagtaa

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