KEGG   Homo sapiens (human): 9958
Entry
9958              CDS       T01001                                 
Symbol
USP15, UNPH-2, UNPH4
Name
(RefSeq) ubiquitin specific peptidase 15
  KO
K21343  ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04137  Mitophagy - animal
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    9958 (USP15)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    9958 (USP15)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    9958 (USP15)
   04121 Ubiquitin system [BR:hsa04121]
    9958 (USP15)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     9958 (USP15)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   9958 (USP15)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    9958 (USP15)
Ubiquitin system [BR:hsa04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    9958 (USP15)
SSDB
Motif
Pfam: UCH Ubiquitin_3 DUSP UCH_1 USP7_C2 USP7_ICP0_bdg Choline_bind_1
Other DBs
NCBI-GeneID: 9958
NCBI-ProteinID: NP_001239007
OMIM: 604731
HGNC: 12613
Ensembl: ENSG00000135655
UniProt: Q9Y4E8
Structure
Position
12:62260404..62416389
AA seq 981 aa
MAEGGAADLDTQRSDIATLLKTSLRKGDTWYLVDSRWFKQWKKYVGFDSWDKYQMGDQNV
YPGPIDNSGLLKDGDAQSLKEHLIDELDYILLPTEGWNKLVSWYTLMEGQEPIARKVVEQ
GMFVKHCKVEVYLTELKLCENGNMNNVVTRRFSKADTIDTIEKEIRKIFSIPDEKETRLW
NKYMSNTFEPLNKPDSTIQDAGLYQGQVLVIEQKNEDGTWPRGPSTPKSPGASNFSTLPK
ISPSSLSNNYNNMNNRNVKNSNYCLPSYTAYKNYDYSEPGRNNEQPGLCGLSNLGNTCFM
NSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVTPR
AFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVVAE
EAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMKKERTLEVYL
VRMDPLTKPMQYKVVVPKIGNILDLCTALSALSGIPADKMIVTDIYNHRFHRIFAMDENL
SSIMERDDIYVFEININRTEDTEHVIIPVCLREKFRHSSYTHHTGSSLFGQPFLMAVPRN
NTEDKLYNLLLLRMCRYVKISTETEETEGSLHCCKDQNINGNGPNGIHEEGSPSEMETDE
PDDESSQDQELPSENENSQSEDSVGGDNDSENGLCTEDTCKGQLTGHKKRLFTFQFNNLG
NTDINYIKDDTRHIRFDDRQLRLDERSFLALDWDPDLKKRYFDENAAEDFEKHESVEYKP
PKKPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSY
SRYMRDKLDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYGGMGGGHYTAFAKNKD
DGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQDTFSGTGFFPLDRETKGASAATGIPLE
SDEDSNDNDNDIENENCMHTN
NT seq 2946 nt   +upstreamnt  +downstreamnt
atggcggaaggcggagcggcggatctggacacccagcggtctgacatcgcgacgctgctc
aaaacctcgctccggaaaggggacacctggtacctagtcgatagtcgctggttcaaacag
tggaaaaaatatgttggctttgacagttgggacaaataccagatgggagatcaaaatgtg
tatcctggacccattgataactctggacttctcaaagatggtgatgcccagtcacttaag
gaacaccttattgatgaattggattacatactgttgccaactgaaggttggaataaactt
gtcagctggtacacattgatggaaggtcaagagccaatagcacgaaaggtggttgaacag
ggtatgtttgtaaagcactgcaaagtagaagtatatctcacagaattgaagctatgtgaa
aatggaaacatgaataatgttgtaactcgaagatttagcaaagctgacacaatagataca
attgaaaaggaaataagaaaaatcttcagtattccagatgaaaaggagaccagattgtgg
aacaaatacatgagtaacacatttgaaccactgaataaaccagacagcaccattcaggat
gctggtttataccaaggacaggtattagtgatagaacagaaaaatgaagatggaacatgg
ccaaggggtccttctactcctaagtccccaggtgcatccaatttttcaactttaccaaag
atctctccttcatctctatcaaataattataacaacatgaacaacagaaatgtgaaaaac
tcaaattactgtcttccatcatataccgcttataagaactatgattattcggaacctgga
agaaacaatgaacagccaggcctctgtggcctaagtaacttgggaaatacgtgtttcatg
aactcagctattcagtgtttgagcaacacacctccacttactgagtatttcctcaatgat
aagtatcaagaagaactgaattttgacaatcccttaggaatgagaggtgaaatagctaaa
tcttatgccgaactgatcaagcaaatgtggtctggaaagtttagctacgtcaccccaaga
gcctttaagacacaggtaggacgttttgcacctcagttctctggatatcagcagcaagac
tgtcaagaactgttagctttcctattagatggattacatgaggatttgaatagaattagg
aaaaaaccatatatacaattaaaagatgcagatggaaggccagataaggtggttgccgaa
gaagcctgggaaaaccatttaaaacgaaatgattctatcatagtagatatatttcatggc
cttttcaaatcaactttagtttgtcctgagtgtgctaagatttcagtaacatttgatcct
ttttgttacttgacacttccattgcccatgaaaaaagaacgcaccttggaagtttactta
gttagaatggatccacttaccaaacctatgcagtacaaagtggttgtccccaaaattgga
aacatattagatctttgtacagcattgtctgctttgtcaggaatacctgcagataagatg
atagttactgatatatacaatcatagatttcacagaatattcgctatggatgaaaacctt
agtagtattatggaacgggatgatatttatgtgtttgaaattaacatcaataggacagaa
gatacagagcacgtgattattcctgtttgcctaagagaaaaattcagacactcgagttat
acccaccatactggttcttcactttttggtcagccctttcttatggctgtaccacgaaac
aatactgaagacaaactttataatctcctgctcttgagaatgtgccgatatgtcaaaata
tctactgaaactgaagaaactgaaggatccctacactgctgtaaggaccaaaatattaat
gggaatggcccaaatggcatacatgaagaaggctcaccaagtgaaatggaaacagatgag
ccagatgatgaatccagccaggatcaagaacttccctcagagaatgaaaacagtcagtct
gaagattcagttggaggagataatgattctgaaaatggattatgtactgaggatacttgc
aaaggtcaactcacgggacacaaaaaacgattgtttacattccagttcaacaacttaggc
aatactgatatcaactacatcaaagatgataccaggcatataagatttgatgataggcag
cttaggctagatgaaagatcttttcttgctttggattgggatcctgatttgaaaaaaaga
tattttgatgaaaatgctgctgaggactttgaaaaacatgaaagtgtggagtataaacct
cctaaaaaaccctttgtgaaattaaaagattgcattgaactttttacaacaaaagaaaag
ctaggtgctgaagatccctggtattgtccgaattgtaaagaacatcagcaagccacaaag
aaattggatttatggtccctgcctccagtacttgtagtacatctcaagcgattttcttac
agtcgatacatgagagacaagttggataccttagttgattttcctatcaatgacttggat
atgtcggaattcttaattaatccaaatgcaggtccttgccgctataatctgattgctgtt
tccaaccactatggagggatgggaggaggacactatactgcttttgcaaaaaataaagat
gatggaaaatggtactattttgatgacagtagtgtctccactgcatctgaagaccaaatt
gtgtccaaagcagcatatgtactcttctaccagagacaagacactttcagtggaactggc
ttttttcctcttgaccgagaaactaaaggtgcttcagctgccactggcatcccattagaa
agtgatgaagatagcaatgataatgacaatgatatagaaaatgaaaactgtatgcacact
aactaa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (44)   
   RefSeq(nuc) (16)   
   GenBank (14)   
   EMBL (14)   
3D Structure (15)   
   PDB (15)   
Protein domain (7)   
   Pfam (7)   
All databases (116)   

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