KEGG   Homo sapiens (human): 348
Entry
348               CDS       T01001                                 
Symbol
APOE, AD2, APO-E, ApoE4, LDLCQ5, LPG
Name
(RefSeq) apolipoprotein E
  KO
K04524  apolipoprotein E
Organism
hsa  Homo sapiens (human)
Pathway
hsa04979  Cholesterol metabolism
hsa05010  Alzheimer disease
Disease
H00056  Alzheimer disease
H00156  Hyperlipoproteinemia, type III
H00887  Lipoprotein glomerulopathy
H01168  Sea-blue histiocyte disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    348 (APOE)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    348 (APOE)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    348 (APOE)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    348 (APOE)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   348 (APOE)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Others
   348 (APOE)
SSDB
Motif
Pfam: Apolipoprotein ApoLp-III Phage_Mu_Gam Prominin Apo-CIII MSP1_C YtxH CHASE6_C DIT1_PvcA LEDGF Sos7 Fzo_mitofusin Adhesin_P1_N Phasin Exonuc_VII_L TetR_C_24 RE_HindIII
Other DBs
NCBI-GeneID: 348
NCBI-ProteinID: NP_000032
OMIM: 107741
HGNC: 613
Ensembl: ENSG00000130203
UniProt: P02649 A0A0S2Z3D5
Structure
Position
19:44905796..44909393
AA seq 317 aa
MKVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQT
LSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQA
RLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVY
QAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMG
SRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEK
VQAAVGTSAAPVPSDNH
NT seq 954 nt   +upstreamnt  +downstreamnt
atgaaggttctgtgggctgcgttgctggtcacattcctggcaggatgccaggccaaggtg
gagcaagcggtggagacagagccggagcccgagctgcgccagcagaccgagtggcagagc
ggccagcgctgggaactggcactgggtcgcttttgggattacctgcgctgggtgcagaca
ctgtctgagcaggtgcaggaggagctgctcagctcccaggtcacccaggaactgagggcg
ctgatggacgagaccatgaaggagttgaaggcctacaaatcggaactggaggaacaactg
accccggtggcggaggagacgcgggcacggctgtccaaggagctgcaggcggcgcaggcc
cggctgggcgcggacatggaggacgtgtgcggccgcctggtgcagtaccgcggcgaggtg
caggccatgctcggccagagcaccgaggagctgcgggtgcgcctcgcctcccacctgcgc
aagctgcgtaagcggctcctccgcgatgccgatgacctgcagaagcgcctggcagtgtac
caggccggggcccgcgagggcgccgagcgcggcctcagcgccatccgcgagcgcctgggg
cccctggtggaacagggccgcgtgcgggccgccactgtgggctccctggccggccagccg
ctacaggagcgggcccaggcctggggcgagcggctgcgcgcgcggatggaggagatgggc
agccggacccgcgaccgcctggacgaggtgaaggagcaggtggcggaggtgcgcgccaag
ctggaggagcaggcccagcagatacgcctgcaggccgaggccttccaggcccgcctcaag
agctggttcgagcccctggtggaagacatgcagcgccagtgggccgggctggtggagaag
gtgcaggctgccgtgggcaccagcgccgcccctgtgcccagcgacaatcactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (12)   
   KEGG DISEASE (4)   
   OMIM (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (15)   
   OC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (45)   
   RefSeq(nuc) (5)   
   GenBank (20)   
   EMBL (20)   
3D Structure (28)   
   PDB (28)   
Protein domain (17)   
   Pfam (17)   
All databases (138)   

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