KEGG   Homo sapiens (human): 59340
Entry
59340             CDS       T01001                                 
Symbol
HRH4, AXOR35, BG26, GPCR105, GPRv53, H4, H4R, HH4R
Name
(RefSeq) histamine receptor H4
  KO
K04152  histamine receptor H4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Adriforant: D11819
Histamine: D08040<US>
Toreforant (DG01866): D10735 D10736
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    59340 (HRH4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    59340 (HRH4)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Histamine
    59340 (HRH4)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7tm_4 MPS-4
Other DBs
NCBI-GeneID: 59340
NCBI-ProteinID: NP_067637
OMIM: 606792
HGNC: 17383
Ensembl: ENSG00000134489
UniProt: Q9H3N8
Structure
Position
18:24460637..24479974
AA seq 390 aa
MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS
DFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAV
SYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYILAITSF
LEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSA
STEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARR
LAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPL
CHKRFQKAFLKIFCIKKQPLPSQHSRSVSS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccagatactaatagcacaatcaatttatcactaagcactcgtgttactttagcattt
tttatgtccttagtagcttttgctataatgctaggaaatgctttggtcattttagctttt
gtggtggacaaaaaccttagacatcgaagtagttatttttttcttaacttggccatctct
gacttctttgtgggtgtgatctccattcctttgtacatccctcacacgctgttcgaatgg
gattttggaaaggaaatctgtgtattttggctcactactgactatctgttatgtacagca
tctgtatataacattgtcctcatcagctatgatcgatacctgtcagtctcaaatgctgtg
tcttatagaactcaacatactggggtcttgaagattgttactctgatggtggccgtttgg
gtgctggccttcttagtgaatgggccaatgattctagtttcagagtcttggaaggatgaa
ggtagtgaatgtgaacctggatttttttcggaatggtacatccttgccatcacatcattc
ttggaattcgtgatcccagtcatcttagtcgcttatttcaacatgaatatttattggagc
ctgtggaagcgtgatcatctcagtaggtgccaaagccatcctggactgactgctgtctct
tccaacatctgtggacactcattcagaggtagactatcttcaaggagatctctttctgca
tcgacagaagttcctgcatcctttcattcagagagacagaggagaaagagtagtctcatg
ttttcctcaagaaccaagatgaatagcaatacaattgcttccaaaatgggttccttctcc
caatcagattctgtagctcttcaccaaagggaacatgttgaactgcttagagccaggaga
ttagccaagtcactggccattctcttaggggtttttgctgtttgctgggctccatattct
ctgttcacaattgtcctttcattttattcctcagcaacaggtcctaaatcagtttggtat
agaattgcattttggcttcagtggttcaattcctttgtcaatcctcttttgtatccattg
tgtcacaagcgctttcaaaaggctttcttgaaaatattttgtataaaaaagcaacctcta
ccatcacaacacagtcggtcagtatcttcttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (4)   
   KEGG DRUG (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (29)   
   RefSeq(nuc) (3)   
   GenBank (13)   
   EMBL (13)   
3D Structure (2)   
   PDB (2)   
Protein domain (4)   
   Pfam (4)   
All databases (65)   

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