KEGG   Homo sapiens (human): 10114
Entry
10114             CDS       T01001                                 
Symbol
HIPK3, DYRK6, FIST3, PKY, YAK1
Name
(RefSeq) homeodomain interacting protein kinase 3
  KO
K08826  homeodomain interacting protein kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    10114 (HIPK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    10114 (HIPK3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     10114 (HIPK3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  DYRK family [OT]
   10114 (HIPK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo Pkinase_fungal TCAD9 APH RIO1
Other DBs
NCBI-GeneID: 10114
NCBI-ProteinID: NP_005725
OMIM: 604424
HGNC: 4915
Ensembl: ENSG00000110422
UniProt: Q9H422
Structure
Position
11:33256672..33357023
AA seq 1215 aa
MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTYVNGRNFGNSHPPTKGS
AFQTKIPFNRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQAHVQAPQIGAWRNRLHFLE
GPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTTGEG
DYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQI
EVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIR
PILQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYL
QSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGE
QLLNVGTKSTRFFCKETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDVAHVNTV
MDLEGSDLLAEKADRREFVSLLKKMLLIDADLRITPAETLNHPFVNMKHLLDFPHSNHVK
SCFHIMDICKSHLNSCDTNNHNKTSLLRPVASSSTATLTANFTKIGTLRSQALTTSAHSV
VHHGIPLQAGTAQFGCGDAFQQTLIICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPA
VQPLQIRPGVLSQTWSGRTQQMLVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISC
SNHYNSVMPQPLLTNQITLSAPQPVSVGIAHVVWPQPATTKKNKQCQNRGILVKLMEWEP
GREEINAFSWSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCETS
IRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLDCEACQ
STLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDEEQESSCDTVDGSPTSDSSGH
DSPFAESTFVEDTHENTELVSSADTETKPAVCSVVVPPVELENGLNADEHMANTDSICQP
LIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQHLNFSQVQHFGSGHQEWNGNFGHRRQQAY
IPTSVTSNPFTLSHGSPNHTAVHAHLAGNTHLGGQPTLLPYPSSATLSSAAPVAHLLASP
CTSRPMLQHPTYNISHPSGIVHQVPVGLNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYT
GFPLSPTKLSQYPYM
NT seq 3648 nt   +upstreamnt  +downstreamnt
atggcctcacaagtcttggtctacccaccatatgtttatcaaactcagtcaagtgccttt
tgtagtgtgaagaaactcaaagtagagccaagcagttgtgtattccaggaaagaaactat
ccacggacctatgtgaatggtagaaactttggaaattctcatcctcccactaagggtagt
gcttttcagacaaagataccatttaatagacctcgaggacacaacttttcattgcagaca
agtgctgttgttttgaaaaacactgcaggtgctacaaaggtcatagcagctcaggcacag
caagctcacgtgcaggcacctcagattggggcgtggcgaaacagattgcatttcctagaa
ggcccccagcgatgtggattgaagcgcaagagtgaggagttggataatcatagcagcgca
atgcagattgtcgatgaattgtccatacttcctgcaatgttgcaaaccaacatgggaaat
ccagtgacagttgtgacagctaccacaggatcaaaacagaattgtaccactggagaaggt
gactatcagttagtacagcatgaagtcttatgctccatgaaaaatacttacgaagtcctt
gattttcttggtcgaggcacgtttggccaggtagttaaatgctggaaaagagggacaaat
gaaattgtagcaatcaaaattttgaagaatcatccttcttatgcccgtcaaggtcaaata
gaagtgagcatattagcaaggctcagtactgaaaatgctgatgaatataactttgtacga
gcttatgaatgctttcagcaccgtaaccatacttgtttagtctttgagatgctggaacaa
aacttgtatgactttctgaaacaaaataaatttagtcccctgccactaaaagtgattcgg
cccattcttcaacaagtggccactgcactgaaaaaattgaaaagtcttggtttaattcat
gctgatctcaagccagagaatattatgttggtggatcctgttcggcagccttacagggtt
aaagtaatagactttgggtcggccagtcatgtatcaaagactgtttgttcaacatatcta
caatctcggtactacagagctccagagattatattggggttgccattttgtgaagccata
gacatgtggtcattgggatgtgtgattgcagaattatttcttggatggccgctctaccca
ggagccttggagtatgatcagattcgatacatttctcagactcaaggtttgccaggagaa
cagttgttaaatgtgggtactaaatccacaagatttttttgcaaagaaacagatatgtct
cattctggttggagattaaagacattggaagagcatgaggcagagacaggaatgaagtct
aaagaagccagaaaatacattttcaacagtctggatgatgtagcgcatgtgaacacagtg
atggatttggaaggaagtgatcttttggctgagaaagctgatagaagagaatttgttagt
ctgttgaagaaaatgttgctgattgatgcagatttaagaattactccagctgagaccctg
aaccatccttttgttaatatgaaacatcttctagatttccctcatagcaaccatgtaaag
tcctgttttcatattatggatatttgtaagtcccacctaaattcatgtgacacaaataat
cacaacaaaacttcacttttaagaccagttgcttcaagcagtactgctacactgactgca
aattttactaaaatcggaacattaagaagtcaggcattgaccacatctgctcattcagtt
gtgcaccatggaatacctctgcaggcaggaactgctcagtttggttgtggtgatgctttt
cagcagacattgattatctgtcccccagctattcaaggtattcctgcaacacatggtaaa
cccaccagttattcaataagggtagataatacagttccacttgtaactcaggccccagct
gtgcagccactacagatccgaccaggagttctttctcagacgtggtctggtagaacacag
cagatgctggtgcctgcctggcaacaggtgacacccctggctcctgctactactacacta
acttctgagagtgtggctggttcacacaggcttggagactgggggaagatgatttcatgc
agcaatcattataactcagtgatgccgcagcctcttctgaccaatcagataactttatct
gcccctcagccagttagtgtggggattgcacatgttgtctggcctcagcctgccactacc
aagaaaaataaacagtgccagaacagaggtattttggtaaaactaatggaatgggagcca
ggaagagaggaaataaatgctttcagttggagtaattcattacagaataccaatatccca
cattcagcatttatttctccaaagataattaatgggaaagatgtcgaggaagtaagttgt
atagaaacacaggacaatcagaactcagaaggagaggcaagaaattgctgtgaaacatct
atcagacaggactctgattcatcagtttcagacaaacagcggcaaaccatcattattgcc
gactccccgagtcctgcagtgagtgtcatcactatcagcagtgacactgatgaggaagag
acttcccagagacattcactcagagaatgtaaaggtagtctagattgtgaagcttgccag
agcactttgaatattgatcggatgtgttcattaagtagtcctgatagtactctgagtacc
agctcctcagggcagtccagcccatccccctgcaagagaccgaatagtatgtcagatgaa
gagcaagaaagtagttgtgatacggtggatggctctccgacatctgactcttccgggcat
gacagtccatttgcagagagcacttttgtggaggacactcatgaaaacacagaattggta
tcctctgctgacacagaaaccaagccagctgtctgttctgttgtggtgccaccagtggaa
ctagaaaatggcttaaatgccgatgagcatatggcaaacacagattctatatgccagcca
ttaataaaaggacgatctgcccctggaagattaaaccagccttctgcagtgggtactcgt
cagcaaaaattgacatcagcattccagcagcagcatttgaacttcagtcaggttcagcac
tttggatctgggcatcaagagtggaatggaaactttgggcacagaagacagcaagcttat
attcctactagtgttaccagtaatccattcactctttctcatggaagtcccaatcacaca
gcagtgcatgcccacctggctggaaatacacacctcggaggacagcctactctacttcca
tacccatcatcagccaccctcagtagtgctgcaccagtggcccacctgttagcctctccg
tgtacctcaagacctatgttacagcatccaacttataatatctcccatcccagtggcata
gttcaccaagtcccagtgggcttaaatccccgtctgttaccatccccaaccattcatcag
actcagtacaaaccaatcttcccaccacattcttacattgcagcatcacctgcatatact
ggatttccactgagtccaacaaaactcagccagtatccatatatgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (41)   
   RefSeq(nuc) (9)   
   GenBank (16)   
   EMBL (16)   
3D Structure (2)   
   PDB (2)   
Protein domain (7)   
   Pfam (7)   
All databases (89)   

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