KEGG   Homo sapiens (human): 10126
Entry
10126             CDS       T01001                                 
Symbol
DNAL4, MRMV3, PIG27
Name
(RefSeq) dynein axonemal light chain 4
  KO
K10412  dynein axonemal light chain 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04814  Motor proteins
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N01159  Mutation-caused aberrant TUBA4A to retrograde axonal transport
N01160  Mutation-caused aberrant SOD1 to retrograde axonal transport
Disease
H01287  Congenital mirror movements
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    10126 (DNAL4)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    10126 (DNAL4)
   05016 Huntington disease
    10126 (DNAL4)
   05022 Pathways of neurodegeneration - multiple diseases
    10126 (DNAL4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    10126 (DNAL4)
   04812 Cytoskeleton proteins [BR:hsa04812]
    10126 (DNAL4)
Cilium and associated proteins [BR:hsa03037]
 Motile cilia and associated proteins
  Dynein arm
   10126 (DNAL4)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     10126 (DNAL4)
SSDB
Motif
Pfam: Dynein_light DUF3109 Ground-like
Other DBs
NCBI-GeneID: 10126
NCBI-ProteinID: NP_005731
OMIM: 610565
HGNC: 2955
Ensembl: ENSG00000100246
UniProt: O96015
Position
22:complement(38778508..38794143)
AA seq 105 aa
MGETEGKKDEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKET
MDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS
NT seq 318 nt   +upstreamnt  +downstreamnt
atgggagaaacagaagggaagaaagatgaggctgattataagcgactgcagaccttccct
ctggtcaggcactcggacatgccagaggagatgcgcgtggagaccatggagctatgtgtc
acagcctgtgagaaattctccaacaacaacgagagcgccgccaagatgatcaaagagaca
atggacaagaagttcggctcctcctggcacgtggtgatcggcgagggctttgggtttgag
atcacccacgaggtgaagaacctcctctacctgtacttcgggggcaccctggctgtgtgc
gtctggaagtgctcctga

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