KEGG   Homo sapiens (human): 10203
Entry
10203             CDS       T01001                                 
Symbol
CALCRL, CGRPR, CRLR, LMPHM8
Name
(RefSeq) calcitonin receptor like receptor
  KO
K04577  calcitonin receptor-like
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
Disease
H00535  Lymphatic malformation
Drug target
Atogepant: D11313<US>
Davalintide (DG01352): D09600 D09601
Erenumab: D10928<JP/US>
Rimegepant (DG01845): D10662 D10663<US>
Telcagepant (DG01353): D09391 D09392
Ubrogepant: D10673<US>
Zavegepant (DG03122): D11898 D11899<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    10203 (CALCRL)
 09150 Organismal Systems
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    10203 (CALCRL)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    10203 (CALCRL)
G protein-coupled receptors [BR:hsa04030]
 Secretin receptor family
  Calcium-regulating peptide
   Calcitonin
    10203 (CALCRL)
SSDB
Motif
Pfam: 7tm_2 HRM
Other DBs
NCBI-GeneID: 10203
NCBI-ProteinID: NP_001258680
OMIM: 114190
HGNC: 16709
Ensembl: ENSG00000064989
UniProt: Q16602
Structure
Position
2:complement(187341964..187448252)
AA seq 461 aa
MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA
EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT
WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL
FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL
IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA
ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI
AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS
YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
NT seq 1386 nt   +upstreamnt  +downstreamnt
atggagaaaaagtgtaccctgtattttctggttctcttgcctttttttatgattcttgtt
acagcagaattagaagagagtcctgaggactcaattcagttgggagttactagaaataaa
atcatgacagctcaatatgaatgttaccaaaagattatgcaagaccccattcaacaagca
gaaggcgtttactgcaacagaacctgggatggatggctctgctggaacgatgttgcagca
ggaactgaatcaatgcagctctgccctgattactttcaggactttgatccatcagaaaaa
gttacaaagatctgtgaccaagatggaaactggtttagacatccagcaagcaacagaaca
tggacaaattatacccagtgtaatgttaacacccacgagaaagtgaagactgcactaaat
ttgttttacctgaccataattggacacggattgtctattgcatcactgcttatctcgctt
ggcatattcttttatttcaagagcctaagttgccaaaggattaccttacacaaaaatctg
ttcttctcatttgtttgtaactctgttgtaacaatcattcacctcactgcagtggccaac
aaccaggccttagtagccacaaatcctgttagttgcaaagtgtcccagttcattcatctt
tacctgatgggctgtaattacttttggatgctctgtgaaggcatttacctacacacactc
attgtggtggccgtgtttgcagagaagcaacatttaatgtggtattattttcttggctgg
ggatttccactgattcctgcttgtatacatgccattgctagaagcttatattacaatgac
aattgctggatcagttctgatacccatctcctctacattatccatggcccaatttgtgct
gctttactggtgaatctttttttcttgttaaatattgtacgcgttctcatcaccaagtta
aaagttacacaccaagcggaatccaatctgtacatgaaagctgtgagagctactcttatc
ttggtgccattgcttggcattgaatttgtgctgattccatggcgacctgaaggaaagatt
gcagaggaggtatatgactacatcatgcacatccttatgcacttccagggtcttttggtc
tctaccattttctgcttctttaatggagaggttcaagcaattctgagaagaaactggaat
caatacaaaatccaatttggaaacagcttttccaactcagaagctcttcgtagtgcgtct
tacacagtgtcaacaatcagtgatggtccaggttatagtcatgactgtcctagtgaacac
ttaaatggaaaaagcatccatgatattgaaaatgttctcttaaaaccagaaaatttatat
aattga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (11)   
   KEGG DRUG (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (40)   
   RefSeq(nuc) (8)   
   GenBank (16)   
   EMBL (16)   
3D Structure (23)   
   PDB (23)   
Protein domain (2)   
   Pfam (2)   
All databases (103)   

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