KEGG   Homo sapiens (human): 10210
Entry
10210             CDS       T01001                                 
Symbol
TOPORS, LUN, P53BP3, RP31, TP53BPL
Name
(RefSeq) TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
  KO
K10631  E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Disease
H00527  Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    10210 (TOPORS)
   03036 Chromosome and associated proteins [BR:hsa03036]
    10210 (TOPORS)
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    10210 (TOPORS)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     10210 (TOPORS)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    10210 (TOPORS)
  UBL E3 ligases
   10210 (TOPORS)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Centriole proteins
    10210 (TOPORS)
Cilium and associated proteins [BR:hsa03037]
 Primary cilia and associated proteins
  Other primary cilia associated proteins
   10210 (TOPORS)
SSDB
Motif
Pfam: zf-C3HC4 zf-C3HC4_2 zf-RING_2 zf-C3HC4_3 zf-RING_UBOX zf-rbx1 zf-RING_5 zf-C3HC4_4 zf-ANAPC11 Rad50_zn_hook zf-RING_4
Other DBs
NCBI-GeneID: 10210
NCBI-ProteinID: NP_005793
OMIM: 609507
HGNC: 21653
Ensembl: ENSG00000197579
UniProt: Q9NS56
Position
9:complement(32540544..32552586)
AA seq 1045 aa
MGSQPPLGSPLSREEGEAPPPAPASEGRRRSRRVRLRGSCRHRPSFLGCRELAASAPARP
APASSEIMASAAKEFKMDNFSPKAGTSKLQQTVPADASPDSKCPICLDRFDNVSYLDRCL
HKFCFRCVQEWSKNKAECPLCKQPFDSIFHSVRAEDDFKEYVLRPSYNGSFVTPDRRFRY
RTTLTRERNASVYSPSGPVNRRTTTPPDSGVLFEGLGISTRPRDVEIPQFMRQIAVRRPT
TADERSLRKIQEQDIINFRRTLYRAGARVRNIEDGGRYRDISAEFFRRNPACLHRLVPWL
KRELTVLFGAHGSLVNIVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFAR
SPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDET
PGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVI
VGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLG
KDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSS
DSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTL
SLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSY
RRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTA
STGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNES
DTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDN
ASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKDVVTIEAEFG
VLDKECDIATLSNNLNNANKTVDNIPPLAASVEQTLDVREESTFVSDLENQPSNIVSLQT
EPSRQLPSPRTSLMSVCLGRDCDMS
NT seq 3138 nt   +upstreamnt  +downstreamnt
atggggtcgcagccgccgctggggtctccgctgtctcgcgaggagggtgaagcgcccccg
cctgctcccgcttcggagggtaggcggagaagtcgccgggtacgccttcgcggatcctgc
cgacaccgacctagctttctgggctgccgggagctcgcggcgagcgccccagccaggcct
gcgccggcatcctccgagataatggcatcagctgctaaggaatttaaaatggacaacttt
tcacctaaagctggcactagcaaattgcaacagacagtaccagctgatgcatctcctgat
tctaagtgtcctatatgcttggatagatttgataatgtgtcttacttagatcgctgctta
cataagttctgttttcgctgtgtacaggagtggtcaaaaaacaaagctgaatgcccacta
tgtaaacagccctttgattctattttccattctgtgagggcagaagatgacttcaaggag
tatgtcctaaggccttcgtataatggttcttttgtcacccctgatcgacgatttcgctac
cgtacaactctgacaagggaacgaaatgcttctgtgtattcacctagtggtcctgtgaac
agaagaacaacaactccaccggatagtggagtactgtttgaagggttaggcatttcaaca
agacctagagatgttgaaattcctcagtttatgagacagattgcagtaaggaggccaact
acggcagatgaaagatctttgcggaaaattcaagaacaagatattattaattttagacga
actctttatcgtgctggtgctcgagttagaaatattgaagatggtggccgctacagggat
atttcagctgaatttttccgtagaaatccagcttgccttcacagattagtcccctggtta
aaacgtgaacttacagttctttttggagctcatggatctttagtgaatattgtccagcat
attatcatgagtaatgttactcgctatgacttggagagtcaggcatttgtgtctgattta
agaccatttttacttaatcgaactgagcattttatacatgaatttatcagttttgcccga
tctccttttaacatggcagcctttgaccagcatgccaattatgattgccctgctccttca
tacgaagaaggcagccattctgattcttcagtcataacaatatctccagatgaggctgag
acccaagagctggatattaatgtagccactgttagtcaggcaccatgggatgatgaaact
ccaggaccatcttactcaagctcagagcaggtacacgttactatgtcttctcttttaaat
acttctgacagttcagatgaagaacttgtcacaggaggagccacgtctcagatacaagga
gtacaaaccaatgacgacctaaataatgacagtgatgattcttcagataattgtgtcatt
gttgggtttgttaaaccactagctgagaggaccccagaacttgttgaactgtcctctgat
tctgaggacttaggttcttatgagaaaatggagacagtgaagacacaagaacaggagcaa
tcttacagttctggtgatagcgatgttagtagatgctcatctccacactctgtccttgga
aaggatgaacaaataaataaaggtcattgtgattctagtacaagaatcaaatcaaagaag
gaagagaaacgatctacatcattgtcatctcccagaaacctgaactcatctgtaagagga
gacagagtatattctccatataaccatagacacagaaagaggggaagatcaagaagttca
gattcacgttctcagagtagaagtgggcatgatcagaagaatcatagaaagcatcatggg
aagaaaagaatgaaaagtaaacgatccagaagcagggaaagtagcagacctagagggaga
agagacaaaaagagatcaagaactagagatagcagttggtccagaagaagccaaactctg
tctctaagtagtgaaagcacaagcagatcaaggtctcgtagcagtgatcatggtaaaaga
agatcacggagcagaaatagagatcgttattatttaagaaataattatggaagcagatac
aaatgggagtatacttattacagtagaaacaaggacagggatgggtacgaatcatcttac
aggaggaggactctgtccagagctcattattctagacagtcttcaagtccagaatttaga
gttcagtccttttctgaaagaacaaatgctaggaaaaaaaataatcacagtgagaggaag
tattactactatgaaaggcacagatcaaggagcctgtctagtaacagatcaaggactgca
tctaccgggactgaccgggtgagaaatgaaaagcctggagggaaacgaaaatacaaaaca
cggcatttggagggtactaacgaagtggctcagccatctcgtgaatttgcttctaaagca
aaggacagtcattaccaaaaatcttcatcaaaattggatggaaactacaaaaatgagagt
gataccttttcagacagccgatcatcagacagagagacaaaacacaaaaggagaaaaagg
aagacccggagcctaagtgtagagatagtttatgaaggaaaagctactgatacaactaaa
caccataaaaagaaaaagaagaaacataagaagaagcataagaaacaccatggagataat
gcttcacgttccccagttgtaattaccattgacagtgacagtgataaggattctgaagta
aaggaggatacagaatgtgacaatagtggtcctcaagaccctctacaaaatgagtttttg
gctccttccttggaaccatttgaaactaaagatgtagttacaatagaagctgaatttggt
gtgctggacaaggaatgtgatattgccacacttagtaacaacttgaataatgccaacaaa
actgtagataatattccacctctggcagcttcagttgaacaaactctcgatgtaagagaa
gagagcacctttgtttctgatttggagaaccagcccagtaacattgtgtctcttcaaact
gagccatcaaggcaattgccatcgccacggacatcattaatgtcagtatgtcttggtaga
gactgtgatatgtcttaa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (26)   
   RefSeq(nuc) (2)   
   GenBank (12)   
   EMBL (12)   
Protein domain (11)   
   Pfam (11)   
All databases (71)   

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