KEGG   Homo sapiens (human): 10320
Entry
10320             CDS       T01001                                 
Symbol
IKZF1, CVID13, Hs.54452, IK1, IKAROS, LYF1, LyF-1, PPP1R92, PRO0758, ZNFN1A1
Name
(RefSeq) IKAROS family zinc finger 1
  KO
K09220  IKAROS family zinc finger protein
Organism
hsa  Homo sapiens (human)
Disease
H00088  Common variable immunodeficiency
Drug target
Zelebrudomide: D12858
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    10320 (IKZF1)
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    10320 (IKZF1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     10320 (IKZF1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 others
    10320 (IKZF1)
SSDB
Motif
Pfam: zf-H2C2_2 zf-C2H2 zf-C2H2_4 zf-C2H2_11 zf-H2C2_5 GAGA
Other DBs
NCBI-GeneID: 10320
NCBI-ProteinID: NP_006051
OMIM: 603023
HGNC: 13176
Ensembl: ENSG00000185811
UniProt: Q13422 R9R4D9
Structure
Position
7:50303455..50405101
AA seq 519 aa
MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVASNVKVE
TQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCD
ICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNY
ACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGTLYPVI
KEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYE
KENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPR
SNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAP
HARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIH
MGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS
NT seq 1560 nt   +upstreamnt  +downstreamnt
atggatgctgatgagggtcaagacatgtcccaagtttcagggaaggaaagcccccctgta
agcgatactccagatgagggcgatgagcccatgccgatccccgaggacctctccaccacc
tcgggaggacagcaaagctccaagagtgacagagtcgtggccagtaatgttaaagtagag
actcagagtgatgaagagaatgggcgtgcctgtgaaatgaatggggaagaatgtgcggag
gatttacgaatgcttgatgcctcgggagagaaaatgaatggctcccacagggaccaaggc
agctcggctttgtcgggagttggaggcattcgacttcctaacggaaaactaaagtgtgat
atctgtgggatcatttgcatcgggcccaatgtgctcatggttcacaaaagaagccacact
ggagaacggcccttccagtgcaatcagtgcggggcctcattcacccagaagggcaacctg
ctccggcacatcaagctgcattccggggagaagcccttcaaatgccacctctgcaactac
gcctgccgccggagggacgccctcactggccacctgaggacgcactccgttggtaaacct
cacaaatgtggatattgtggccgaagctataaacagcgaagctctttagaggaacataaa
gagcgctgccacaactacttggaaagcatgggccttccgggcacactgtacccagtcatt
aaagaagaaactaatcacagtgaaatggcagaagacctgtgcaagataggatcagagaga
tctctcgtgctggacagactagcaagtaacgtcgccaaacgtaagagctctatgcctcag
aaatttcttggggacaagggcctgtccgacacgccctacgacagcagcgccagctacgag
aaggagaacgaaatgatgaagtcccacgtgatggaccaagccatcaacaacgccatcaac
tacctgggggccgagtccctgcgcccgctggtgcagacgcccccgggcggttccgaggtg
gtcccggtcatcagcccgatgtaccagctgcacaagccgctcgcggagggcaccccgcgc
tccaaccactcggcccaggacagcgccgtggagaacctgctgctgctctccaaggccaag
ttggtgccctcggagcgcgaggcgtccccgagcaacagctgccaagactccacggacacc
gagagcaacaacgaggagcagcgcagcggtctcatctacctgaccaaccacatcgccccg
cacgcgcgcaacgggctgtcgctcaaggaggagcaccgcgcctacgacctgctgcgcgcc
gcctccgagaactcgcaggacgcgctccgcgtggtcagcaccagcggggagcagatgaag
gtgtacaagtgcgaacactgccgggtgctcttcctggatcacgtcatgtacaccatccac
atgggctgccacggcttccgtgatccttttgagtgcaacatgtgcggctaccacagccag
gaccggtacgagttctcgtcgcacataacgcgaggggagcaccgcttccacatgagctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (108)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (105)   
DNA sequence (162)   
   RefSeq(nuc) (112)   
   GenBank (25)   
   EMBL (25)   
3D Structure (3)   
   PDB (3)   
Protein domain (6)   
   Pfam (6)   
All databases (298)   

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