KEGG   Homo sapiens (human): 10389
Entry
10389             CDS       T01001                                 
Symbol
SCML2
Name
(RefSeq) Scm polycomb group protein like 2
  KO
K11465  sex comb on midleg-like protein 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa03083  Polycomb repressive complex
Network
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N01577  Gene silencing by methylation of H3K27 and ubiquitination of H2AK119
N01585  Deubiquitination of H2AK119
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    10389 (SCML2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    10389 (SCML2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    Canonical PRC1 (PRC1.2/1.4)
     PRC1.4 specific proteins
      10389 (SCML2)
SSDB
Motif
Pfam: MBT SLED RBR SAM_1 SAM_PNT SAM_2
Other DBs
NCBI-GeneID: 10389
NCBI-ProteinID: NP_006080
OMIM: 300208
HGNC: 10581
Ensembl: ENSG00000102098
UniProt: Q9UQR0
Structure
Position
X:complement(18239313..18355118)
AA seq 700 aa
MGQTVNEDSMDVKKENQEKTPQSSTSSVQRDDFHWEEYLKETGSISAPSECFRQSQIPPV
NDFKVGMKLEARDPRNATSVCIATVIGITGARLRLRLDGSDNRNDFWRLVDSPDIQPVGT
CEKEGDLLQPPLGYQMNTSSWPMFLLKTLNGSEMASATLFKKEPPKPPLNNFKVGMKLEA
IDKKNPYLICPATIGDVKGDEVHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTGDVLQPP
GTSVPIVKNIAKTESSPSEASQHSMQSPQKTTLILPTQQVRRSSRIKPPGPTAVPKRSSS
VKNITPRKKGPNSGKKEKPLPVICSTSAASLKSLTRDRGMLYKDVASGPCKIVMSTVCVY
VNKHGNFGPHLDPKRIQQLPDHFGPGPVNVVLRRIVQACVDCALETKTVFGYLKPDNRGG
EVITASFDGETHSIQLPPVNSASFALRFLENFCHSLQCDNLLSSQPFSSSRGHTHSSAEH
DKNQSAKEDVTERQSTKRSPQQTVPYVVPLSPKLPKTKEYASEGEPLFAGGSAIPKEENL
SEDSKSSSLNSGNYLNPACRNPMYIHTSVSQDFSRSVPGTTSSPLVGDISPKSSPHEVKF
QMQRKSEAPSYIAVPDPSVLKQGFSKDPSTWSVDEVIQFMKHTDPQISGPLADLFRQHEI
DGKALFLLKSDVMMKYMGLKLGPALKLCYYIEKLKEGKYS
NT seq 2103 nt   +upstreamnt  +downstreamnt
atgggacaaacagtgaatgaagattccatggatgtcaagaaggagaatcaagagaaaact
cctcagtcaagtacatcttctgtacaaagggatgatttccactgggaggagtatttgaaa
gagactgggtctataagtgctccttcagagtgcttccgtcagtctcagattccacctgtg
aatgatttcaaagttggtatgaaattggaagcccgtgaccctcgcaatgccacttcagta
tgtattgctacggttattggaattactggggccaggttacggttacgactggatggtagt
gacaacagaaatgatttttggaggcttgtcgattccccagacatacaacctgttgggaca
tgtgaaaaggaaggagacttacttcaacctccactagggtaccagatgaatacatcctcc
tggccgatgttcctcttaaagacactaaatgggtctgaaatggcatctgccacattattt
aagaaggaaccaccaaagcccccactaaataattttaaagtggggatgaaactggaagct
attgacaaaaagaacccgtatctcatctgtcctgcgaccattggagatgttaaaggggat
gaagttcatatcacatttgatggctggagtggagcttttgattactggtgcaagtatgat
tctcgagatattttcccagctgggtggtgtcgcctgacaggagatgtattacaaccccca
ggaactagtgttcctattgtaaagaatatagcaaaaacagagtcttctccttccgaagca
agccagcattcaatgcagtctccacagaaaactactctaatattaccaacacagcaggtc
aggagatcaagtcgaattaaaccacctggacctactgcagtccccaaaaggagcagttct
gttaaaaatatcacaccaaggaaaaaaggtccaaactcaggaaaaaaggaaaaacctttg
cccgtgatatgttctacatctgcagcttctctaaaatcgctgaccagagaccgtggcatg
ttatataaagatgtcgcttctgggccatgtaaaatagtgatgtctacagtctgtgtctat
gtaaacaaacatggaaactttggccctcatctggatcccaagagaatccagcagctgcct
gaccacttcggcccgggcccggtgaatgtggtgcttcgccggattgtgcaggcctgtgtg
gattgtgcccttgaaactaaaactgtttttggatacctgaagccagataatcgtggagga
gaagtgataactgcctcctttgatggggaaactcattccatccagctccctccagtgaac
agtgcatcatttgctcttcgctttcttgagaacttctgccacagtctgcagtgtgataac
cttttgagtagccagccttttagttcttccaggggtcatactcacagctctgcagagcat
gataaaaatcagtcagcaaaagaagatgtaacagaaaggcaaagcaccaaacgatctcct
cagcaaactgtaccatatgttgttcctctctctcctaagctccccaaaacaaaggagtat
gcgtctgaaggagaaccattgtttgctgggggaagtgccattcccaaagaggagaatctt
tcagaagattctaagagctcatcactaaattcaggaaattatttgaatcctgcctgtaga
aatcctatgtatattcatacttcagtctcccaggatttttctcgaagtgtgccaggcacc
acaagttcaccactagttggggacatatcccccaagagcagtccccatgaagttaaattc
caaatgcagaggaaaagtgaagctccaagttatatagctgtacctgatcccagtgtcctg
aaacaaggcttctctaaggacccttcaacctggtctgtggatgaagtgatacagtttatg
aaacatacagatcctcagatatcaggccccctcgccgacctcttcaggcaacatgaaatt
gatgggaaggctctgttcctactcaagagtgatgtgatgatgaagtatatggggctgaag
ctggggccagcattaaagctgtgttactacattgaaaagcttaaagaaggaaaatacagt
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (30)   
   RefSeq(nuc) (10)   
   GenBank (10)   
   EMBL (10)   
3D Structure (5)   
   PDB (5)   
Protein domain (6)   
   Pfam (6)   
All databases (81)   

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