KEGG   Homo sapiens (human): 10395
Entry
10395             CDS       T01001                                 
Symbol
DLC1, ARHGAP7, HP, STARD12, p122-RhoGAP
Name
(RefSeq) DLC1 Rho GTPase activating protein
  KO
K20632  deleted in liver cancer protein
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10395 (DLC1)
Membrane trafficking [BR:hsa04131]
 Others
  Rho GTPase associated proteins
   Rho GTPase-activating proteins
    10395 (DLC1)
SSDB
Motif
Pfam: START RhoGAP SAM_2 Tra1_central RE_NgoPII
Other DBs
NCBI-GeneID: 10395
NCBI-ProteinID: NP_001335010
OMIM: 604258
HGNC: 2897
Ensembl: ENSG00000164741
UniProt: Q96QB1
Structure
Position
8:complement(13083361..13604620)
AA seq 1528 aa
MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASMEKDATLNVDRKEKCVS
LPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLC
LTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVSSNSWGIAGETELALVKESGE
RKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKDIAPEKQLLNSAVIAQQRRKPDP
PKDENERSTCNVVQNEFLDTPCTNRGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFS
QHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQVRLRKRKEIREDRDRARLDSMVLLIM
KLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTEST
DLPSSTPVANSGTKPKTTAIQGISEKEKAEIEAKEACDWLRATGFPQYAQLYEDFLFPID
ISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWTF
QRDSKRWSRLEEFDVFSPKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSST
GSLPSHAPPSEDAATPRTNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTA
KSKTRSLLKRMESLKLKSSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALN
GNRINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFD
PFNQSTFNNVVEQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRT
GSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENE
DIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTT
PSDLDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQI
NCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPL
TVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEG
QSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREV
LQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQ
KDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSAD
YQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVPEE
ILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKG
ACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSF
GHLCAAEVVKIRDSFSNQNTETKDTKSR
NT seq 4587 nt   +upstreamnt  +downstreamnt
atgtctgtagctatcagaaagagaagctgggaagaacatgtgacccactggatgggacag
ccttttaattctgatgatcgtaacacagcatgtcatcatggactagtagctgacagcttg
caggcaagtatggaaaaagatgcaactctaaatgtggaccgcaaagagaagtgtgtttca
ctacctgactgctgtcatggatcagagctgagagattttcctgggaggccaatgggtcat
ctttcaaaggatgtggacgaaaatgacagccatgaaggtgaagatcagtttctttctctg
gaagccagcacagaaacactagtgcatgtttctgatgaggataacaatgctgatttatgc
cttacagatgataaacaggttttaaatacccaagggcagaaaacatcaggccaacatatg
atccaaggagcaggctccttagaaaaggcactgcccatcatacaaagtaaccaagtttct
tctaactcctggggaatagctggtgaaactgaattagcactggtaaaagaaagtggggag
agaaaagttactgactctataagtaaaagcctggagctttgcaatgaaataagcttaagt
gaaataaaagatgcacccaaagtaaatgcagtggatactttgaacgtgaaagatattgca
cctgagaaacaattgcttaactctgctgtaattgctcagcaacgaaggaaacctgacccc
cctaaagatgaaaatgaaagaagcacctgcaatgtagtacaaaatgagttcttggatact
ccttgcacaaacagaggactgccattattaaaaacagattttggaagctgccttctgcag
cctccttcctgccccaatggaatgtcagctgaaaatggcctggagaagagtggtttttca
caacatcaaaacaaaagtccaccaaaggtcaaggcagaagatggcatgcagtgtttacaa
ttaaaggagaccctggccacccaggaacccacagataaccaagtcagacttcgtaagaga
aaggaaataagagaagatcgagatagggcgcggctggactccatggtgctgctgattatg
aaactggaccagcttgatcaggacatagaaaatgccctcagcaccagctcctctccatca
ggcacaccaacaaacctgcggcggcacgttcctgatctggaatcaggatctgaaagtgga
gcagataccatttcagtaaatcagacacgagtaaatttgtcttctgacactgagtccacg
gacctcccatcttccactccagtagccaattctggaaccaaacccaagactacggctatt
caaggtatttcagagaaggaaaaggctgaaattgaagccaaggaagcttgtgattggcta
cgggcaactggtttcccccagtatgcacagctttatgaagatttcctgttccccatcgat
atttccttggtcaagagagagcatgattttttggacagagatgccattgaggctctatgc
aggcgtctaaatactttaaacaaatgtgcggtgatgaagctagaaattagtcctcatcgg
aaacgaagtgacgattcagacgaggatgagccttgtgccatcagtggcaaatggactttc
caaagggacagcaagaggtggtcccggcttgaagagtttgatgtcttttctccaaaacaa
gacctggtccctgggtccccagacgactcccacccgaaggacggccccagccccggaggc
acgctgatggacctcagcgagcgccaggaggtgtcttccgtccgcagcctcagcagcact
ggcagcctccccagccacgcgccccccagcgaggatgctgccaccccccggactaactcc
gtcatcagcgtttgctcctccagcaacttggcaggcaatgacgactctttcggcagcctg
ccctctcccaaggaactgtccagcttcagcttcagcatgaaaggccacgaaaaaactgcc
aagtccaagacgcgcagtctgctgaaacggatggagagcctgaagctcaagagctcccat
cacagcaagcacaaagcgccctcaaagctggggttgatcatcagcgggcccatcttgcaa
gaggggatggatgaggagaagctgaagcagctcaactgcgtggagatctccgccctcaat
ggcaaccgcatcaacgtccccatggtacgaaagaggagcgtttccaactccacgcagacc
agcagcagcagcagccagtcggagaccagcagcgcggtcagcacgcccagccctgttacg
aggacccggagcctcagtgcgtgcaacaagcgggtgggcatgtacttagagggcttcgat
cctttcaatcagtcaacatttaacaacgtggtggagcagaactttaagaaccgcgagagc
tacccagaggacacggtgttctacatccctgaagatcacaagcctggcactttccccaaa
gctctcaccaatggcagtttctccccctcggggaataacggctctgtgaactggaggacg
ggaagcttccacggccctggccacatcagcctcaggagggaaaacagtagcgacagcccc
aaggaactgaagagacgcaattcttccagctccatgagcagccgcctgagcatctacgac
aacgtgccgggctccatcctctactccagttcaggggacctggcggatctggagaacgag
gacatcttccccgagctggacgacatcctctaccacgtgaaggggatgcagcggatagtc
aatcagtggtcggagaagttttctgatgagggagattcggactcagccctggactcggtc
tctccctgcccgtcctctccaaaacagatacacctggatgtggacaacgaccgaaccaca
cccagcgacctggacagcacaggcaactccctgaatgaaccggaagagccctccgagatc
ccggaaagaagggattctggggttggggcttccctaaccaggtccaacaggcaccgactg
agatggcacagtttccagagctcacatcggccaagcctcaactctgtatcactacagatt
aactgccagtctgtggcccagatgaacctgctgcagaaatactcactcctaaagctaacg
gccctgctggagaaatacacaccttctaacaagcatggttttagctgggccgtgcccaag
ttcatgaagaggatcaaggttccagactacaaggaccggagtgtgtttggggtcccactg
acggtcaacgtgcagcgcacaggacaaccgttgcctcagagcatccagcaggccatgcga
tacctccggaaccattgtttggatcaggttgggctcttcagaaaatcgggggtcaagtcc
cggattcaggctctgcgccagatgaatgaaggtgccatagactgtgtcaactacgaagga
cagtctgcttatgacgtggcagacatgctgaagcagtattttcgagatcttcctgagcca
ctaatgacgaacaaactctcggaaacctttctacagatctaccaatatgtgcccaaggac
cagcgcctgcaggccatcaaggctgccatcatgctgctgcctgacgagaaccgggaggtt
ctgcagaccctgctttatttcctgagcgatgtcacagcagccgtaaaagaaaaccagatg
accccaaccaacctggccgtgtgcttagcgccttccctcttccatctcaacaccctgaag
agagagaattcctctcccagggtaatgcaaagaaaacaaagtttgggcaaaccagatcag
aaagatttgaatgaaaacctagctgccactcaagggctggcccatatgatcgccgagtgc
aagaagcttttccaggttcccgaggaaatgagccgatgtcgtaattcctataccgaacaa
gagctgaagcccctcactctggaagcactcgggcacctgggtaatgatgactcagctgac
taccaacacttcctccaggactgtgtggatggcctgtttaaagaagtcaaagagaagttt
aaaggctgggtcagctactccacttcggagcaggctgagctgtcctataagaaggtgagc
gaaggaccccctctgaggctttggaggtcagtcattgaagtccctgctgtgccagaggaa
atcttaaagcgcctacttaaagaacagcacctctgggatgtagacctgttggattcaaaa
gtgatcgaaattctggacagccaaactgaaatttaccagtatgtccaaaacagtatggca
cctcatcctgctcgagactacgttgttttaagaacctggaggactaatttacccaaagga
gcctgtgcccttttactaacctctgtggatcacgatcgcgcacctgtggtgggtgtgagg
gttaatgtgctcttgtccaggtatttgattgaaccctgtgggccaggaaaatccaaactc
acctacatgtgcagagttgacttaaggggccacatgccagaatggtacacaaaatctttt
ggacatttgtgtgcagctgaagttgtaaagatccgggattccttcagtaaccagaacact
gaaaccaaagacaccaaatctaggtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (28)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (26)   
DNA sequence (76)   
   RefSeq(nuc) (26)   
   GenBank (25)   
   EMBL (25)   
3D Structure (6)   
   PDB (6)   
Protein domain (5)   
   Pfam (5)   
All databases (149)   

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