KEGG   Homo sapiens (human): 10434
Entry
10434             CDS       T01001                                 
Symbol
LYPLA1, APT-1, APT1, LPL-I, LPL1, hAPT1
Name
(RefSeq) lysophospholipase 1
  KO
K06128  lysophospholipase I [EC:3.1.1.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00564  Glycerophospholipid metabolism
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    10434 (LYPLA1)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    10434 (LYPLA1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.5  lysophospholipase
     10434 (LYPLA1)
SSDB
Motif
Pfam: Abhydrolase_2 Abhydrolase_1 Hydrolase_4 Abhydrolase_6 Abhydrolase_3 Cutinase Palm_thioest Mbeg1-like FSH1 BD-FAE Lipase_3 Esterase
Other DBs
NCBI-GeneID: 10434
NCBI-ProteinID: NP_006321
OMIM: 605599
HGNC: 6737
Ensembl: ENSG00000120992
UniProt: O75608 Q6IAQ1
Structure
Position
8:complement(54046367..54101947)
AA seq 230 aa
MCGNNMSTPLPAIVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSSHIKYICPHAPVRP
VTLNMNVAMPSWFDIIGLSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQ
GGALSLYTALTTQQKLAGVTALSCWLPLRASFPQGPIGGANRDISILQCHGDCDPLVPLM
FGSLTVEKLKTLVNPANVTFKTYEGMMHSSCQQEMMDVKQFIDKLLPPID
NT seq 693 nt   +upstreamnt  +downstreamnt
atgtgcggcaataacatgtcaaccccgctgcccgccatcgtgcccgccgcccggaaggcc
accgctgcggtgattttcctgcatggattgggagatactgggcacggatgggcagaagcc
tttgcaggtatcagaagttcacatatcaaatatatctgcccgcatgcgcctgttaggcct
gttacattaaatatgaacgtggctatgccttcatggtttgatattattgggctttcacca
gattcacaggaggatgaatctgggattaaacaggcagcagaaaatataaaagctttgatt
gatcaagaagtgaagaatggcattccttctaacagaattattttgggagggttttctcag
ggaggagctttatctttatatactgcccttaccacacagcagaaactggcaggtgtcact
gcactcagttgctggcttccacttcgggcttcctttccacagggtcctatcggtggtgct
aatagagatatttctattctccagtgccacggggattgtgaccctttggttcccctgatg
tttggttctcttacggtggaaaaactaaaaacattggtgaatccagccaatgtgaccttt
aaaacctatgaaggtatgatgcacagttcgtgtcaacaggaaatgatggatgtcaagcaa
ttcattgataaactcctacctccaattgattga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (31)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (28)   
DNA sequence (66)   
   RefSeq(nuc) (28)   
   GenBank (19)   
   EMBL (19)   
3D Structure (6)   
   PDB (6)   
Protein domain (12)   
   Pfam (12)   
All databases (147)   

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