KEGG   Homo sapiens (human): 10436
Entry
10436             CDS       T01001                                 
Symbol
EMG1, C2F, Grcc2f, NEP1
Name
(RefSeq) EMG1 N1-specific pseudouridine methyltransferase
  KO
K14568  rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03008  Ribosome biogenesis in eukaryotes
Disease
H00616  Bowen-Conradi syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03008 Ribosome biogenesis in eukaryotes
    10436 (EMG1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03009 Ribosome biogenesis [BR:hsa03009]
    10436 (EMG1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.260  rRNA small subunit pseudouridine methyltransferase Nep1
     10436 (EMG1)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  90S particles
   Other 90S particles
    10436 (EMG1)
SSDB
Motif
Pfam: EMG1
Other DBs
NCBI-GeneID: 10436
NCBI-ProteinID: NP_006322
OMIM: 611531
HGNC: 16912
Ensembl: ENSG00000126749
UniProt: Q92979
Structure
Position
12:6970913..6997428
AA seq 244 aa
MAAPSDGFKPRERSGGEQAQDWDALPPKRPRLGAGNKIGGRRLIVVLEGASLETVKVGKT
YELLNCDKHKSILLKNGRDPGEARPDITHQSLLMLMDSPLNRAGLLQVYIHTQKNVLIEV
NPQTRIPRTFDRFCGLMVQLLHKLSVRAADGPQKLLKVIKNPVSDHFPVGCMKVGTSFSI
PVVSDVRELVPSSDPIVFVVGAFAHGKVSVEYTEKMVSISNYPLSAALTCAKLTTAFEEV
WGVI
NT seq 735 nt   +upstreamnt  +downstreamnt
atggccgcgcccagtgatggattcaagcctcgtgaacgaagcggtggggagcaggcacag
gactgggatgctctgccacccaagcggccccgactaggggcaggaaacaagatcggaggc
cgtaggcttattgtggtgctggaaggggccagtctggagacagtcaaggtagggaagaca
tatgagctactcaactgtgacaagcacaagtctatattgttgaagaatggacgggaccct
ggggaagcgcggccagatatcacccaccagagtttgctgatgctgatggatagtcccctg
aaccgagctggcttgctacaggtttatatccatacacagaagaatgttctgattgaagtg
aatccccagacccgaattcccagaacctttgaccgcttttgtggcctcatggttcaactt
ttacacaagctcagtgttcgagcagctgatggcccccagaagcttttgaaggtaattaag
aatccagtatcagatcactttccagttggatgtatgaaagttggcacttctttttccatc
ccggttgtcagtgatgtgcgtgagctggtgcccagcagtgatcctattgtttttgtggta
ggggcctttgcccatggcaaggtcagtgtggagtatacagagaagatggtgtccatcagt
aactaccccctttctgctgccctcacctgtgcaaaacttaccacagcctttgaggaagta
tggggggtcatttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (37)   
   RefSeq(nuc) (3)   
   GenBank (17)   
   EMBL (17)   
3D Structure (4)   
   PDB (4)   
Protein domain (1)   
   Pfam (1)   
All databases (65)   

Download RDF
DBGET integrated database retrieval system