KEGG   Homo sapiens (human): 10499
Entry
10499             CDS       T01001                                 
Symbol
NCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75
Name
(RefSeq) nuclear receptor coactivator 2
  KO
K11255  nuclear receptor coactivator 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
hsa04919  Thyroid hormone signaling pathway
Network
nt06227  Nuclear receptor signaling (cancer)
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    10499 (NCOA2)
   04919 Thyroid hormone signaling pathway
    10499 (NCOA2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    10499 (NCOA2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    10499 (NCOA2)
SSDB
Motif
Pfam: NCOA_u2 PAS_11 DUF4927 DUF1518 Nuc_rec_co-act SRC-1 PAS_3 PAS PAS_9 HLH PAS_4
Other DBs
NCBI-GeneID: 10499
NCBI-ProteinID: NP_001308632
OMIM: 601993
HGNC: 7669
Ensembl: ENSG00000140396
UniProt: Q15596
Structure
Position
8:complement(70109782..70456446)
AA seq 1464 aa
MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT
PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN
TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG
NLFPNQLPGMDMIKQEGDTTRKYC
NT seq 4395 nt   +upstreamnt  +downstreamnt
atgagtgggatgggagaaaatacctctgacccctccagggcagagacaagaaagcgcaag
gaatgtcctgaccaacttggacccagccccaaaaggaacactgaaaaacgtaatcgtgaa
caggaaaataaatatatagaagaacttgcagagttgatttttgcaaattttaatgatata
gacaactttaacttcaaacctgacaaatgtgcaatcttaaaagaaactgtgaagcaaatt
cgtcagatcaaagaacaagagaaagcagcagctgccaacatagatgaagtgcagaagtca
gatgtatcctctacagggcagggtgtcatcgacaaggatgcgctggggcctatgatgctt
gaggcccttgatgggttcttctttgtagtgaacctggaaggcaacgttgtgtttgtgtca
gagaatgtgacacagtatctaaggtataaccaagaagagctgatgaacaaaagtgtatat
agcatcttgcatgttggggaccacacggaatttgtcaaaaacctgctgccaaagtctata
gtaaatgggggatcttggtctggcgaacctccgaggcggaacagccataccttcaattgt
cggatgctggtaaaacctttacctgattcagaagaggagggtcatgataaccaggaagct
catcagaaatatgaaactatgcagtgcttcgctgtctctcaaccaaagtccatcaaagaa
gaaggagaagatttgcagtcctgcttgatttgcgtggcaagaagagttcccatgaaggaa
agaccagttcttccctcatcagaaagttttactactcgccaggatctccaaggcaagatc
acgtctctggataccagcaccatgagagcagccatgaaaccaggctgggaggacctggta
agaaggtgtattcagaagttccatgcgcagcatgaaggagaatctgtgtcctatgctaag
aggcatcatcatgaagtactgagacaaggattggcattcagtcaaatctatcgtttttcc
ttgtctgatggcactcttgttgctgcacaaacgaagagcaaactcatccgttctcagact
actaatgaacctcaacttgtaatatctttacatatgcttcacagagagcagaatgtgtgt
gtgatgaatccggatctgactggacaaacgatggggaagccactgaatccaattagctct
aacagccctgcccatcaggccctgtgcagtgggaacccaggtcaggacatgaccctcagt
agcaatataaattttcccataaatggcccaaaggaacaaatgggcatgcccatgggcagg
tttggtggttctgggggaatgaaccatgtgtcaggcatgcaagcaaccactcctcagggt
agtaactatgcactcaaaatgaacagcccctcacaaagcagccctggcatgaatccagga
cagcccacctccatgctttcaccaaggcatcgcatgagccctggagtggctggcagccct
cgaatcccacccagtcagttttcccctgcaggaagcttgcattcccctgtgggagtttgc
agcagcacaggaaatagccatagttataccaacagctccctcaatgcacttcaggccctc
agcgaggggcacggggtctcattagggtcatcgttggcttcaccagacctaaaaatgggc
aatttgcaaaactccccagttaatatgaatcctcccccactcagcaagatgggaagcttg
gactcaaaagactgttttggactatatggggagccctctgaaggtacaactggacaagca
gagagcagctgccatcctggagagcaaaaggaaacaaatgaccccaacctgcccccggcc
gtgagcagtgagagagctgacgggcagagcagactgcatgacagcaaagggcagaccaaa
ctcctgcagctgctgaccaccaaatctgatcagatggagccctcgcccttagccagctct
ttgtcggatacaaacaaagactccacaggtagcttgcctggttctgggtctacacatgga
acctcgctcaaggagaagcataaaattttgcacagactcttgcaggacagcagttcccct
gtggacttggccaagttaacagcagaagccacaggcaaagacctgagccaggagtccagc
agcacagctcctggatcagaagtgactattaaacaagagccggtgagccccaagaagaaa
gagaatgcactacttcgctatttgctagataaagatgatactaaagatattggtttacca
gaaataacccccaaacttgagagactggacagtaagacagatcctgccagtaacacaaaa
ttaatagcaatgaaaactgagaaggaggagatgagctttgagcctggtgaccagcctggc
agtgagctggacaacttggaggagattttggatgatttgcagaatagtcaattaccacag
cttttcccagacacgaggccaggcgcccctgctggatcagttgacaagcaagccatcatc
aatgacctcatgcaactcacagctgaaaacagccctgtcacacctgttggagcccagaaa
acagcactgcgaatttcacagagcacttttaataacccacgaccagggcaactgggcagg
ttattgccaaaccagaatttaccacttgacatcacattgcaaagcccaactggtgctgga
cctttcccaccaatcagaaacagtagtccctactcagtgatacctcagccaggaatgatg
ggtaatcaagggatgataggaaaccaaggaaatttagggaacagtagcacaggaatgatt
ggtaacagtgcttctcggcctactatgccatctggagaatgggcaccgcagagttcggct
gtgagagtcacctgtgctgctaccaccagtgccatgaaccggccagtccaaggaggtatg
attcggaacccagcagccagcatccccatgaggcccagcagccagcctggccaaagacag
acgcttcagtctcaggtcatgaatatagggccatctgaattagagatgaacatgggggga
cctcagtatagccaacaacaagctcctccaaatcagactgccccatggcctgaaagcatc
ctgcctatagaccaggcgtcttttgccagccaaaacaggcagccatttggcagttctcca
gatgacttgctatgtccacatcctgcagctgagtctccgagtgatgagggagctctcctg
gaccagctgtatctggccttgcggaattttgatggcctggaggagattgatagagcctta
ggaatacccgaactggtcagccagagccaagcagtagatccagaacagttctcaagtcag
gattccaacatcatgctggagcagaaggcgcccgttttcccacagcagtatgcatctcag
gcacaaatggcccagggtagctattctcccatgcaagatccaaactttcacaccatggga
cagcggcctagttatgccacactccgtatgcagcccagaccgggcctcaggcccacgggc
ctagtgcagaaccagccaaatcaactaagacttcaacttcagcatcgcctccaagcacag
cagaatcgccagccacttatgaatcaaatcagcaatgtttccaatgtgaacttgactctg
aggcctggagtaccaacacaggcacctattaatgcacagatgctggcccagagacagagg
gaaatcctgaaccagcatcttcgacagagacaaatgcatcagcaacagcaagttcagcaa
cgaactttgatgatgagaggacaagggttgaatatgacaccaagcatggtggctcctagt
ggtatgccagcaactatgagcaaccctcggattccccaggcaaatgcacagcagtttcca
tttcctccaaactacggaataagtcagcaacctgatccaggctttactggggctacgact
ccccagagcccacttatgtcaccccgaatggcacatacacagagtcccatgatgcaacag
tctcaggccaacccagcctatcaggccccctccgacataaatggatgggcgcaggggaac
atgggcggaaacagcatgttttcccagcagtccccaccacactttgggcagcaagcaaac
accagcatgtacagtaacaacatgaacatcaatgtgtccatggcgaccaacacaggtggc
atgagcagcatgaaccagatgacaggacagatcagcatgacctcagtgacctccgtgcct
acgtcagggctgtcctccatgggtcccgagcaggttaatgatcctgctctgaggggaggc
aacctgttcccaaaccagctgcctggaatggatatgattaagcaggagggagacacaaca
cggaaatattgctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (4)   
   KEGG NETWORK (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (91)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (89)   
DNA sequence (121)   
   RefSeq(nuc) (89)   
   GenBank (16)   
   EMBL (16)   
3D Structure (347)   
   PDB (347)   
Protein domain (11)   
   Pfam (11)   
All databases (593)   

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