KEGG   Homo sapiens (human): 10599
Entry
10599             CDS       T01001                                 
Symbol
SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6
Name
(RefSeq) solute carrier organic anion transporter family member 1B1
  KO
K05043  solute carrier organic anion transporter family, member 1B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04976  Bile secretion
Disease
H00208  Hyperbilirubinemia
H02057  Rotor syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    10599 (SLCO1B1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    10599 (SLCO1B1)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC21/ASLCO: Organic anion transporter
   10599 (SLCO1B1)
SSDB
Motif
Pfam: OATP MFS_1 Kazal_2 Kazal_1 SP24
Other DBs
NCBI-GeneID: 10599
NCBI-ProteinID: NP_006437
OMIM: 604843
HGNC: 10959
Ensembl: ENSG00000134538
UniProt: Q9Y6L6 Q05CV5
Structure
Position
12:21131194..21239796
AA seq 691 aa
MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFE
ISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGY
YRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNML
RGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYV
DLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLE
TNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVF
KYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLS
FYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGIT
YISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAI
QVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCI
KWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASE
NGSVMDEANLESLNKNKHFVPSAGADSETHC
NT seq 2076 nt   +upstreamnt  +downstreamnt
atggaccaaaatcaacatttgaataaaacagcagaggcacaaccttcagagaataagaaa
acaagatactgcaatggattgaagatgttcttggcagctctgtcactcagctttattgct
aagacactaggtgcaattattatgaaaagttccatcattcatatagaacggagatttgag
atatcctcttctcttgttggttttattgacggaagctttgaaattggaaatttgcttgtg
attgtatttgtgagttactttggatccaaactacatagaccaaagttaattggaatcggt
tgtttcattatgggaattggaggtgttttgactgctttgccacatttcttcatgggatat
tacaggtattctaaagaaactaatatcaattcatcagaaaattcaacatcgaccttatcc
acttgtttaattaatcaaattttatcactcaatagagcatcacctgagatagtgggaaaa
ggttgtttaaaggaatctgggtcatacatgtggatatatgtgttcatgggtaatatgctt
cgtggaataggggagactcccatagtaccattggggctttcttacattgatgatttcgct
aaagaaggacattcttctttgtatttaggtatattgaatgcaatagcaatgattggtcca
atcattggctttaccctgggatctctgttttctaaaatgtacgtggatattggatatgta
gatctaagcactatcaggataactcctactgattctcgatgggttggagcttggtggctt
aatttccttgtgtctggactattctccattatttcttccataccattctttttcttgccc
caaactccaaataaaccacaaaaagaaagaaaagcttcactgtctttgcatgtgctggaa
acaaatgatgaaaaggatcaaacagctaatttgaccaatcaaggaaaaaatattaccaaa
aatgtgactggttttttccagtcttttaaaagcatccttactaatcccctgtatgttatg
tttgtgcttttgacgttgttacaagtaagcagctatattggtgcttttacttatgtcttc
aaatacgtagagcaacagtatggtcagccttcatctaaggctaacatcttattgggagtc
ataaccatacctatttttgcaagtggaatgtttttaggaggatatatcattaaaaaattc
aaactgaacaccgttggaattgccaaattctcatgttttactgctgtgatgtcattgtcc
ttttacctattatattttttcatactctgtgaaaacaaatcagttgccggactaaccatg
acctatgatggaaataatccagtgacatctcatagagatgtaccactttcttattgcaac
tcagactgcaattgtgatgaaagtcaatgggaaccagtctgtggaaacaatggaataact
tacatctcaccctgtctagcaggttgcaaatcttcaagtggcaataaaaagcctatagtg
ttttacaactgcagttgtttggaagtaactggtctccagaacagaaattactcagcccat
ttgggtgaatgcccaagagatgatgcttgtacaaggaaattttacttttttgttgcaata
caagtcttgaatttatttttctctgcacttggaggcacctcacatgtcatgctgattgtt
aaaattgttcaacctgaattgaaatcacttgcactgggtttccactcaatggttatacga
gcactaggaggaattctagctccaatatattttggggctctgattgatacaacgtgtata
aagtggtccaccaacaactgtggcacacgtgggtcatgtaggacatataattccacatca
ttttcaagggtctacttgggcttgtcttcaatgttaagagtctcatcacttgttttatat
attatattaatttatgccatgaagaaaaaatatcaagagaaagatatcaatgcatcagaa
aatggaagtgtcatggatgaagcaaacttagaatccttaaataaaaataaacattttgtc
ccttctgctggggcagatagtgaaacacattgttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
3D Structure (6)   
   PDB (6)   
Protein domain (5)   
   Pfam (5)   
All databases (68)   

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