KEGG   Homo sapiens (human): 1073
Entry
1073              CDS       T01001                                 
Symbol
CFL2, NEM7
Name
(RefSeq) cofilin 2
  KO
K05765  cofilin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05133  Pertussis
hsa05170  Human immunodeficiency virus 1 infection
Network
nt06161  Human immunodeficiency virus 1 (HIV-1)
  Element
N00433  CXCR4-GNB/G-RAC signaling pathway
Disease
H00698  Nemaline myopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    1073 (CFL2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    1073 (CFL2)
  09158 Development and regeneration
   04360 Axon guidance
    1073 (CFL2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    1073 (CFL2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    1073 (CFL2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    1073 (CFL2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1073 (CFL2)
   04147 Exosome [BR:hsa04147]
    1073 (CFL2)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Others
    1073 (CFL2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    ADF / Cofilin
     1073 (CFL2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   1073 (CFL2)
SSDB
Motif
Pfam: Cofilin_ADF
Other DBs
NCBI-GeneID: 1073
NCBI-ProteinID: NP_068733
OMIM: 601443
HGNC: 1875
Ensembl: ENSG00000165410
UniProt: Q9Y281 Q549N0
Structure
Position
14:complement(34709113..34714593)
AA seq 166 aa
MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDI
GDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS
KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL
NT seq 501 nt   +upstreamnt  +downstreamnt
atggcttctggagttacagtgaatgatgaagtcatcaaagtttttaatgatatgaaagta
aggaaatcttctacacaagaggagatcaaaaagagaaagaaagcagttctcttctgttta
agcgatgacaaaagacaaataattgtagaggaagcaaagcagatcttggtgggtgacatt
ggtgatactgtagaggacccctacacatcttttgtgaagttgctacctctgaatgattgc
cgatatgctttgtacgatgccacatacgaaacaaaagagtctaagaaagaagacctagta
tttatattctgggctcctgaaagtgcacctttaaaaagcaagatgatttatgctagctct
aaagatgccattaaaaagaaatttacaggtattaaacatgagtggcaagtaaatggcttg
gatgatattaaggaccgttcgacacttggagagaaattgggaggcaatgtagtagtttca
cttgaaggaaaaccattataa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (35)   
   RefSeq(nuc) (5)   
   GenBank (15)   
   EMBL (15)   
3D Structure (2)   
   PDB (2)   
Protein domain (1)   
   Pfam (1)   
All databases (80)   

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