KEGG   Homo sapiens (human): 10818
Entry
10818             CDS       T01001                                 
Symbol
FRS2, FRS1A, FRS2A, FRS2alpha, SNT, SNT-1, SNT1
Name
(RefSeq) fibroblast growth factor receptor substrate 2
  KO
K12461  fibroblast growth factor receptor substrate 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04714  Thermogenesis
hsa04722  Neurotrophin signaling pathway
hsa05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    10818 (FRS2)
  09159 Environmental adaptation
   04714 Thermogenesis
    10818 (FRS2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    10818 (FRS2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:hsa04990]
    10818 (FRS2)
Domain-containing proteins not elsewhere classified [BR:hsa04990]
 Phosphotyrosine binding (PTB) domain-containing proteins
  IRS related family proteins
   10818 (FRS2)
SSDB
Motif
Pfam: IRS
Other DBs
NCBI-GeneID: 10818
NCBI-ProteinID: NP_001036020
OMIM: 607743
HGNC: 16971
Ensembl: ENSG00000166225
UniProt: Q8WU20 L7RTG7
Structure
Position
12:69470388..69579793
AA seq 508 aa
MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYL
CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVER
NNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGE
ESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDP
QILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPS
VNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWE
ARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRDCTPTVF
NFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTA
AMSNLQKALPRDDGTSRKTRHNSTDLPM
NT seq 1527 nt   +upstreamnt  +downstreamnt
atgggtagctgttgtagctgtccagataaagacactgtcccagataaccatcggaacaag
tttaaggtcattaatgtggatgatgatgggaatgagttaggttctggcataatggaactt
acagacacagaactgattttatacacccgcaaacgtgactcagtaaaatggcactacctc
tgcctgcgacgctatggctatgactcgaatctcttttcttttgaaagtggtcgaaggtgt
caaactggacaaggaatctttgcctttaagtgtgcccgtgcagaagaattatttaacatg
ttgcaagagattatgcaaaataatagtataaatgtggtggaagagccagttgtagaaaga
aataatcatcagacagaattggaagtccctagaacacctcgaacacctacaactccagga
tttgctgctcagaacttacctaatggatatccccgatatccctcatttggagatgcttca
tcccatccgtcaagcagacatccttctgtgggaagtgctcgcctgccttcagtaggggaa
gaatctacacatcctttgcttgtggctgaggaacaagtacatacctatgtcaacactaca
ggtgtgcaagaagagcggaaaaaccgcacaagtgtgcatgttccattggaggcgagggtt
tctaacgctgaaagcagcacaccaaaagaagaaccaagtagtattgaggacagggatcct
cagattcttcttgaacctgaaggagtcaaatttgttttagggccaacccctgttcaaaag
cagttaatggaaaaagagaaactggagcaacttggaagagatcaagttagtggaagtgga
gcaaataacacagaatgggacactggctatgacagtgatgaacgaagagatgcaccctct
gttaacaaactggtgtatgaaaatataaatgggctatctatccctagtgcctcaggggtc
aggagaggtcgtctgacatccaccagtacctcagatacccagaatatcaacaactcagct
cagagaagaactgcattattaaactatgaaaatctaccatctttgcctcctgtttgggaa
gcccgcaagctaagtagggatgaagatgacaatttaggaccaaagaccccatctctaaat
ggctaccataataatctagatccaatgcataactatgtaaatacagagaatgtaacagtg
ccagcaagtgctcacaaaatagaatattcaaggcgtcgggactgtacaccaacagtcttt
aactttgatatcagacgcccaagtttagaacacaggcagcttaattacatacaggttgac
ttggaaggtggcagtgactctgacaaccctcagactccaaaaacgcctacaactcccctt
ccacaaacccctaccaggcgcacagagctgtatgccgtgatagacatcgagagaactgct
gctatgtcaaatttgcagaaagcactgccacgagatgatggtacatctaggaaaactaga
cacaatagtactgatctgcccatgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (29)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (26)   
DNA sequence (66)   
   RefSeq(nuc) (26)   
   GenBank (20)   
   EMBL (20)   
3D Structure (2)   
   PDB (2)   
Protein domain (1)   
   Pfam (1)   
All databases (113)   

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