KEGG   Homo sapiens (human): 10993
Entry
10993             CDS       T01001                                 
Symbol
SDS, SDH
Name
(RefSeq) serine dehydratase
  KO
K17989  L-serine/L-threonine ammonia-lyase [EC:4.3.1.17 4.3.1.19]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00270  Cysteine and methionine metabolism
hsa00290  Valine, leucine and isoleucine biosynthesis
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01230  Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    10993 (SDS)
   00270 Cysteine and methionine metabolism
    10993 (SDS)
   00290 Valine, leucine and isoleucine biosynthesis
    10993 (SDS)
Enzymes [BR:hsa01000]
 4. Lyases
  4.3  Carbon-nitrogen lyases
   4.3.1  Ammonia-lyases
    4.3.1.17  L-serine ammonia-lyase
     10993 (SDS)
    4.3.1.19  threonine ammonia-lyase
     10993 (SDS)
SSDB
Motif
Pfam: PALP TPP_enzyme_N DUF4597
Other DBs
NCBI-GeneID: 10993
NCBI-ProteinID: NP_006834
OMIM: 182128
HGNC: 10691
Ensembl: ENSG00000135094
UniProt: P20132 Q8WW81
Structure
Position
12:complement(113392445..113403887)
AA seq 328 aa
MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCKRWAKQGCAHF
VCSSAGNAGMAAAYAARQLGVPATIVVPSTTPALTIERLKNEGATVKVVGELLDEAFELA
KALAKNNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGL
QEVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHP
IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV
IVCGGSNISLAQLRALKEQLGMTNRLPK
NT seq 987 nt   +upstreamnt  +downstreamnt
atgatgtctggagaacccctgcacgtgaagacccccatccgtgacagcatggccctgtcc
aaaatggccggcaccagcgtctacctcaagatggacagtgcccagccctccggctccttc
aagatccggggcattgggcacttctgcaagaggtgggccaagcaaggctgtgcacatttt
gtctgctcctcggcgggcaacgcaggcatggcggctgcatatgcggccaggcaactcggc
gtccccgccaccatcgtggtgcccagcaccacacctgctctcaccattgagcgcctcaag
aatgaaggtgccacagtcaaggtggtgggtgagttattggatgaagccttcgagctggcc
aaggccctagcgaagaacaacccgggttgggtctacattcccccctttgatgaccccctc
atctgggaaggccacgcttccatcgtgaaagagctgaaggagacactgtgggaaaagccg
ggggccatcgcgctgtcagtgggcggcgggggcctgctgtgtggagtggtccaggggctg
caggaggtgggctggggggacgtgcctgtcatcgccatggagacttttggtgcccacagc
ttccacgctgccaccaccgcaggcaaacttgtctccctgcccaagatcaccagtgttgcc
aaggccctgggcgtgaagactgtgggggctcaggccctgaagctgtttcaggaacacccc
attttctctgaagttatctcggaccaggaggctgtggccgccattgagaagttcgtggat
gatgagaagatcctggtggagcccgcctgcggggcagccctggccgctgtctatagccac
gtgatccagaagctccaactggaggggaatctccgaaccccgctgccatccctcgtggtc
atcgtctgcgggggcagcaacatcagcctggcccagctgcgggcgctcaaggaacagctg
ggcatgacaaataggttgcccaagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
3D Structure (2)   
   PDB (2)   
Protein domain (3)   
   Pfam (3)   
All databases (55)   

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