KEGG   Homo sapiens (human): 11040
Entry
11040             CDS       T01001                                 
Symbol
PIM2
Name
(RefSeq) Pim-2 proto-oncogene, serine/threonine kinase
  KO
K08806  proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05200  Pathways in cancer
hsa05221  Acute myeloid leukemia
Network
nt06219  JAK-STAT signaling (cancer)
nt06275  Acute myeloid leukemia
  Element
N00054  Duplication or mutation-activated FLT3 to Jak-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    11040 (PIM2)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    11040 (PIM2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    11040 (PIM2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     11040 (PIM2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  PIM family [OT]
   11040 (PIM2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 11040
NCBI-ProteinID: NP_006866
OMIM: 300295
HGNC: 8987
Ensembl: ENSG00000102096
UniProt: Q9P1W9
Structure
Position
X:complement(48913182..48919024)
AA seq 311 aa
MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAI
KVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPL
PAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKL
IDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFER
DQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKG
GPAPLAWSLLP
NT seq 936 nt   +upstreamnt  +downstreamnt
atgttgaccaagcctctacaggggcctcccgcgccccccgggacccccacgccgccgcca
ggaggcaaggatcgggaagcgttcgaggccgagtatcgactcggccccctcctgggtaag
gggggctttggcaccgtcttcgcaggacaccgcctcacagatcgactccaggtggccatc
aaagtgattccccggaatcgtgtgctgggctggtcccccttgtcagactcagtcacatgc
ccactcgaagtcgcactgctatggaaagtgggtgcaggtggtgggcaccctggcgtgatc
cgcctgcttgactggtttgagacacaggagggcttcatgctggtcctcgagcggcctttg
cccgcccaggatctctttgactatatcacagagaagggcccactgggtgaaggcccaagc
cgctgcttctttggccaagtagtggcagccatccagcactgccattcccgtggagttgtc
catcgtgacatcaaggatgagaacatcctgatagacctacgccgtggctgtgccaaactc
attgattttggttctggtgccctgcttcatgatgaaccctacactgactttgatgggaca
agggtgtacagccccccagagtggatctctcgacaccagtaccatgcactcccggccact
gtctggtcactgggcatcctcctctatgacatggtgtgtggggacattccctttgagagg
gaccaggagattctggaagctgagctccacttcccagcccatgtctccccagactgctgt
gccctaatccgccggtgcctggcccccaaaccttcttcccgaccctcactggaagagatc
ctgctggacccctggatgcaaacaccagccgaggatgtacccctcaacccctccaaagga
ggccctgcccctttggcctggtccttgctaccctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (14)   
   RefSeq(nuc) (4)   
   GenBank (5)   
   EMBL (5)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (48)   

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