KEGG   Homo sapiens (human): 11091
Entry
11091             CDS       T01001                                 
Symbol
WDR5, BIG-3, BIG3, CFAP89, SWD3
Name
(RefSeq) WD repeat domain 5
  KO
K14963  COMPASS component SWD3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03083  Polycomb repressive complex
hsa04934  Cushing syndrome
Network
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N01614  Activation of PRC2.2 by ubiquitination of H2AK119 in germline genes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    11091 (WDR5)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    11091 (WDR5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    11091 (WDR5)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HAT complexes
    ATAC complex
     11091 (WDR5)
    NSL complex
     11091 (WDR5)
   HMT complexes
    COMPASS/SET1 complex
     11091 (WDR5)
    COMPASS/SET1 complex (yeast)
     11091 (WDR5)
    MLL-HCF complex
     11091 (WDR5)
    MLL3/MLL4 complex
     11091 (WDR5)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     11091 (WDR5)
SSDB
Motif
Pfam: WD40 ANAPC4_WD40 NBCH_WD40 eIF2A Nup160 WD40_like RMC1_N PROPPIN Ge1_WD40 WDR54 VID27 CDtoxinA Nucleoporin_N TolB_like
Other DBs
NCBI-GeneID: 11091
NCBI-ProteinID: NP_060058
OMIM: 609012
HGNC: 12757
Ensembl: ENSG00000196363
UniProt: P61964
Structure
Position
9:134135199..134159968
AA seq 334 aa
MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWL
ASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK
CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN
RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKL
WDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH
TDVVISTACHPTENIIASAALENDKTIKLWKSDC
NT seq 1005 nt   +upstreamnt  +downstreamnt
atggcgacggaggagaagaagcccgagaccgaggccgccagagcacagccaaccccttcg
tcatccgccactcagagcaagcctacacctgtgaagccaaactatgctctaaagttcacc
cttgctggccacaccaaagcagtgtcctccgtgaaattcagcccgaatggagagtggctg
gcaagttcatctgctgataaacttattaaaatttggggcgcgtatgatgggaaatttgag
aaaaccatatctggtcacaagctgggaatatccgatgtagcctggtcgtcagattctaac
cttcttgtttctgcctcagatgacaaaaccttgaagatatgggacgtgagctcgggcaag
tgtctgaaaaccctgaagggacacagtaattatgtcttttgctgcaacttcaatccccag
tccaaccttattgtctcaggatcctttgacgaaagcgtgaggatatgggatgtgaaaaca
gggaagtgcctcaagactttgccagctcactcggatccagtctcggccgttcattttaat
cgtgatggatccttgatagtttcaagtagctatgatggtctctgtcgcatctgggacacc
gcctcaggccagtgcctgaagacgctcatcgatgacgacaacccccccgtgtcttttgtg
aagttctccccgaacggcaaatacatcctggccgccacgctggacaacactctgaagctc
tgggactacagcaaggggaagtgcctgaagacgtacactggccacaagaatgagaaatac
tgcatatttgccaatttctctgttactggtgggaagtggattgtgtctggctcagaggat
aaccttgtttacatctggaaccttcagacgaaagagattgtacagaaactacaaggccac
acagatgtcgtgatctcaacagcttgtcacccaacagaaaacatcatcgcctctgctgcg
ctagaaaatgacaaaacaattaaactgtggaagagtgactgctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (58)   
   KEGG ORTHOLOGY (1)   
   RefGene (49)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (33)   
   RefSeq(nuc) (15)   
   GenBank (9)   
   EMBL (9)   
3D Structure (146)   
   PDB (146)   
Protein domain (14)   
   Pfam (14)   
All databases (276)   

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