KEGG   Homo sapiens (human): 11099
Entry
11099             CDS       T01001                                 
Symbol
PTPN21, PTPD1, PTPRL10
Name
(RefSeq) protein tyrosine phosphatase non-receptor type 21
  KO
K18025  tyrosine-protein phosphatase non-receptor type 14/21 [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    11099 (PTPN21)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     11099 (PTPN21)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    11099 (PTPN21)
SSDB
Motif
Pfam: Y_phosphatase FERM_M FERM_C FERM_N DSPc Y_phosphatase3 PTPlike_phytase SNX17-27-31_F1_FERM
Other DBs
NCBI-GeneID: 11099
NCBI-ProteinID: NP_008970
OMIM: 603271
HGNC: 9651
Ensembl: ENSG00000070778
UniProt: Q16825
Structure
Position
14:complement(88465778..88555007)
AA seq 1174 aa
MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELRE
VTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEPTVYFGVVFYVPSVSQLQQEITRYQY
YLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEKV
LEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEG
IFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVAR
HKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQD
NLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNPS
ITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGSS
YAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSVP
ELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRVH
HSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSAS
AAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDFE
EESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRTT
AEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGMK
KTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTEY
ERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVSV
SGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHNT
VTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSY
LEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRVL
DMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
NT seq 3525 nt   +upstreamnt  +downstreamnt
atgccactgccatttgggttgaaactgaaacgcacccggcgctacacggtgtccagcaag
agttgcctggttgcccggatccaactgcttaataacgagtttgtggagttcaccctgtcc
gtggagagcactggccaggaaagcctcgaggccgtggcccagaggctggagctgcgggag
gtcacttacttcagcctctggtactacaacaagcaaaatcagcgccggtgggtagatttg
gaaaaacctttgaagaagcagctggataaatatgcattggaacctaccgtctattttgga
gtggtgttttatgtgccttcagtttctcagctgcagcaggagattaccaggtatcagtat
tatctgcaactgaagaaagatatcttggaaggaagtattccttgtaccttagaacaagca
attcagctagcaggcttagctgttcaagcggattttggtgactttgatcagtatgaatcc
caggactttcttcagaaatttgccttgtttcctgtgggatggttacaagatgaaaaagta
ttggaagaagcaacccaaaaagtggccttactacatcagaaatacagagggctcacagct
cctgatgctgaaatgctgtacatgcaggaggtagagagaatggatggctatggagaagag
agctaccctgctaaggatagccaaggaagtgacatatccattggagcgtgtcttgaaggt
atctttgtgaaacacaagaatggaaggcatcctgtggtatttaggtggcatgacattgcc
aacatgtcccacaacaagtccttttttgcattagagctggcaaataaagaggagaccatt
caatttcaaactgaagacatggaaacagcaaaatacatttggagactctgtgttgcgcga
cacaagttttacagactaaaccagtgtaacctgcaaactcagactgtcacagtgaaccca
atcaggaggaggtcttcttcaaggatgtctctgcctaaaccccagccctacgtgatgcct
cccccaccgcagttgcactataatggacattatacagaaccatatgcttcttcccaagat
aacctctttgtgcccaaccagaacggatactactgtcactctcagacaagcttggataga
gcccagattgacctcaacggtcggatccgtaatggcagtgtctacagtgcacacagcacc
aactccttaaataatcctcagccctacttgcagccctcgccgatgtcgtccaaccctagc
atcaccgggagtgacgtcatgaggcctgactacctcccgtcccatcggcacagcgccgtg
atacccccgtcctaccgccccaccccagactatgagactgtgatgaagcagctcaacagg
ggcctggtgcatgcggaacggcagagccactcgctgcgaaacctcaacatcggcagctcg
tacgcctacagcaggcccgcggcgctggtctacagccagcccgagatccgcgagcacgca
cagctcccctcgccagcggccgcacactgcccgttcagcctgagctacagcttccacagc
ccgtctccctacccctaccctgccgagcggcggcccgtggtgggcgcggtcagcgtgccg
gagctgaccaatgcgcagctgcaggcgcaggactacccgtctcccaacatcatgcggacg
caggtgtaccggccacccccaccctacccgccccccaggcccgccaacagcacgccagac
ctgtcccgccacctttacatcagcagcagcaaccccgacctcatcacgcggcgcgtgcac
cactcggtgcaaacgttccaggaggacagcctgcccgtggcgcactcgctgcaggaggtc
agcgagcccctcaccgccgcgcgccacgcgcagctgcacaaacggaacagcatcgaggtg
gccgggctcagccacggcctggagggcctgcggctcaaggagcgcaccctatccgcgtcg
gcggcagaggtggcgccgcgagccgtctcggtgggctcccagcccagcgttttcaccgag
aggacacagcgagaagggccggaggaggcggagggcttgaggtacggccataagaagtcc
ctgtcggacgccaccatgctaatccacagcagcgaggaggaggaggacgaggacttcgag
gaggagagcggggcccgggcgcctcctgcacgtgcgcgcgagcctcggcccggcctggcc
caggacccacctggctgccctcgcgtcctgctcgccgggcccctgcacatcctggagccc
aaggcccacgtcccagacgcggagaagaggatgatggacagcagccccgtccgcacgacc
gcagaggcccagcggccctggagagacgggctgctgatgccctccatgtcggagtccgac
ctcaccacgtcaggccgctaccgagcccggagggactctctgaagaaaaggccggtgtcg
gaccttctctctgggaagaagaacatcgtggaagggctcccgcctctagggggaatgaaa
aagactcgagtagatgcaaaaaaaattggtcctcttaaactggctgccctaaatggactc
tccctatctcgagtgcctctgcctgatgaaggaaaggaagtggctaccagagcaacgaat
gatgaaaggtgtaaaattctggaacaacgattagaacaaggaatggtattcacagaatat
gaaagaattcttaagaaacggctagttgatggggagtgctcaacagcacgactccctgaa
aatgcagaaagaaatcgattccaagatgttcttccttatgatgatgtgagagtggagttg
gtcccaactaaagaaaacaacactggttacatcaacgcatcacatattaaggtctctgtc
agtggaatcgaatgggattatattgccacacagggaccattacagaatacctgtcaagat
ttttggcagatggtatgggaacagggaattgcaattatagcaatggtgacagcagaagag
gagggtggaagggagaagagctttaggtactggccacgacttggttccaggcacaacact
gtcacctatggaaggtttaagatcacgacccggttccgcacagactctggctgctatgcc
accacaggcctgaagatgaagcacctccttactgggcaagagaggaccgtctggcacctc
caatacacagactggcctgaacatggctgtccagaagacctcaagggatttttatcatat
cttgaagagatccagtctgttcgacgccatacaaatagcacaagtgatccccaaagcccc
aaccctccgttgttggtccactgcagtgctggggtaggaaggactggcgtggtgattttg
tcggagatcatgatcgcctgcctggaacacaatgaggtgctggacatcccgagagtgctg
gacatgctgaggcaacagagaatgatgctggtgcagactctctgccagtacacatttgtg
tacagagtcctcatccagttcctgaaaagctccaggctcatctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (23)   
   RefSeq(nuc) (9)   
   GenBank (7)   
   EMBL (7)   
3D Structure (4)   
   PDB (4)   
Protein domain (8)   
   Pfam (8)   
All databases (66)   

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