KEGG   Homo sapiens (human): 11214
Entry
11214             CDS       T01001                                 
Symbol
AKAP13, AKAP-13, AKAP-Lbc, ARHGEF13, BRX, HA-3, Ht31, LBC, PRKA13, PROTO-LB, PROTO-LBC, c-lbc, p47
Name
(RefSeq) A-kinase anchoring protein 13
  KO
K16529  A-kinase anchor protein 13
Organism
hsa  Homo sapiens (human)
Pathway
hsa04928  Parathyroid hormone synthesis, secretion and action
hsa05163  Human cytomegalovirus infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    11214 (AKAP13)
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    11214 (AKAP13)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    11214 (AKAP13)
Membrane trafficking [BR:hsa04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    11214 (AKAP13)
SSDB
Motif
Pfam: PH_16 RhoGEF PH C1_1 RII_binding_1 C1_2 Prok-RING_1 Ank_2
Other DBs
NCBI-GeneID: 11214
NCBI-ProteinID: NP_009131
OMIM: 604686
HGNC: 371
Ensembl: ENSG00000170776
UniProt: Q12802
Structure
Position
15:85380603..85749358
AA seq 2813 aa
MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAP
GHDCCETVKVQLCASKEGLPVFVVAEEDFHFVQDEAYDAAQFLATSAGNQQALNFTRFLD
QSGPPSGDVNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDAGPRETLMHFAVRLGLLRLT
WFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLLTEENAGEPDSWSSLSYEIPYG
DCSVRHHRELDIYTLTSESDSHHEHPFPGDGCTGPIFKLMNIQQQLMKTNLKQMDSLMPL
MMTAQDPSSAPETDGQFLPCAPEPTDPQRLSSSEETESTQCCPGSPVAQTESPCDLSSIV
EEENTDRSCRKKNKGVERKGEEVEPAPIVDSGTVSDQDSCLQSLPDCGVKGTEGLSSCGN
RNEETGTKSSGMPTDQESLSSGDAVLQRDLVMEPGTAQYSSGGELGGISTTNVSTPDTAG
EMEHGLMNPDATVWKNVLQGGESTKERFENSNIGTAGASDVHVTSKPVDKISVPNCAPAA
SSLDGNKPAESSLAFSNEETSTEKTAETETSRSREESADAPVDQNSVVIPAAAKDKISDG
LEPYTLLAAGIGEAMSPSDLALLGLEEDVMPHQNSETNSSHAQSQKGKSSPICSTTGDDK
LCADSACQQNTVTSSGDLVAKLCDNIVSESESTTARQPSSQDPPDASHCEDPQAHTVTSD
PVRDTQERADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSHPHPVVPKMEKELVPDQAVI
SDSTFSLANSPGSESVTKDDALSFVPSQKEKGTATPELHTATDYRDGPDGNSNEPDTRPL
EDRAVGLSTSSTAAELQHGMGNTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSLQSVGKA
TLALDSVLTEEGKLLVVSESSAAQEQDKDKAVTCSSIKENALSSGTLQEEQRTPPPGQDT
QQFHEKSISADCAKDKALQLSNSPGASSAFLKAETEHNKEVAPQVSLLTQGGAAQSLVPP
GASLATESRQEALGAEHNSSALLPCLLPDGSDGSDALNCSQPSPLDVGVKNTQSQGKTSA
CEVSGDVTVDVTGVNALQGMAEPRRENISHNTQDILIPNVLLSQEKNAVLGLPVALQDKA
VTDPQGVGTPEMIPLDWEKGKLEGADHSCTMGDAEEAQIDDEAHPVLLQPVAKELPTDME
LSAHDDGAPAGVREVMRAPPSGRERSTPSLPCMVSAQDAPLPKGADLIEEAASRIVDAVI
EQVKAAGALLTEGEACHMSLSSPELGPLTKGLESAFTEKVSTFPPGESLPMGSTPEEATG
SLAGCFAGREEPEKIILPVQGPEPAAEMPDVKAEDEVDFRASSISEEVAVGSIAATLKMK
QGPMTQAINRENWCTIEPCPDAASLLASKQSPECENFLDVGLGRECTSKQGVLKRESGSD
SDLFHSPSDDMDSIIFPKPEEEHLACDITGSSSSTDDTASLDRHSSHGSDVSLSQILKPN
RSRDRQSLDGFYSHGMGAEGRESESEPADPGDVEEEEMDSITEVPANCSVLRSSMRSLSP
FRRHSWGPGKNAASDAEMNHRSSMRVLGDVVRRPPIHRRSFSLEGLTGGAGVGNKPSSSL
EVSSANAEELRHPFSGEERVDSLVSLSEEDLESDQREHRMFDQQICHRSKQQGFNYCTSA
ISSPLTKSISLMTISHPGLDNSRPFHSTFHNTSANLTESITEENYNFLPHSPSKKDSEWK
SGTKVSRTFSYIKNKMSSSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTFSSIPVV
GPISCSQCMKPFTNKDAYTCANCSAFVHKGCRESLASCAKVKMKQPKGSLQAHDTSSLPT
VIMRNKPSQPKERPRSAVLLVDETATTPIFANRRSQQSVSLSKSVSIQNITGVGNDENMS
NTWKFLSHSTDSLNKISKVNESTESLTDEGVGTDMNEGQLLGDFEIESKQLEAESWSRII
DSKFLKQQKKDVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADLLFEQQMVEKLFP
CLDELISIHSQFFQRILERKKESLVDKSEKNFLIKRIGDVLVNQFSGENAERLKKTYGKF
CGQHNQSVNYFKDLYAKDKRFQAFVKKKMSSSVVRRLGIPECILLVTQRITKYPVLFQRI
LQCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVASYEKKVRLNEIYTKTDSKSIMRMKSGQ
MFAKEDLKRKKLVRDGSVFLKNAAGRLKEVQAVLLTDILVFLQEKDQKYIFASLDQKSTV
ISLKKLIVREVAHEEKGLFLISMGMTDPEMVEVHASSKEERNSWIQIIQDTINTLNRDED
EGIPSENEEEKKMLDTRARELKEQLHQKDQKILLLLEEKEMIFRDMAECSTPLPEDCSPT
HSPRVLFRSNTEEALKGGPLMKSAINEVEILQGLVSGNLGGTLGPTVSSPIEQDVVGPVS
LPRRAETFGGFDSHQMNASKGGEKEEGDDGQDLRRTESDSGLKKGGNANLVFMLKRNSEQ
VVQSVVHLYELLSALQGVVLQQDSYIEDQKLVLSERALTRSLSRPSSLIEQEKQRSLEKQ
RQDLANLQKQQAQYLEEKRRREREWEARERELREREALLAQREEEVQQGQQDLEKEREEL
QQKKGTYQYDLERLRAAQKQLEREQEQLRREAERLSQRQTERDLCQVSHPHTKLMRIPSF
FPSPEEPPSPSAPSIAKSGSLDSELSVSPKRNSISRTHKDKGPFHILSSTSQTNKGPEGQ
SQAPASTSASTRLFGLTKPKEKKEKKKKNKTSRSQPGDGPASEVSAEGEEIFC
NT seq 8442 nt   +upstreamnt  +downstreamnt
atgaaacttaatccacagcaagctcccttatatggtgattgtgttgttacagtgctgctt
gctgaagaggacaaagctgaagatgatgtagtgttttacttggtatttttgggttccacc
ctccgtcactgtacaagtactcggaaggtcagttctgatacattggagaccattgctcct
ggtcatgattgttgtgaaacagtgaaggtgcagctctgtgcttccaaagagggccttccc
gtgtttgtggtggctgaagaagactttcatttcgtccaggatgaagcgtatgatgcagct
caattcctagcaaccagtgctggaaatcagcaggctttgaactttacccgttttcttgac
cagtcaggacccccatctggggatgtgaattcccttgataagaagttggtgctggcattc
aggcacctgaagctgcccacggagtggaatgtattggggacagatcagagtttgcatgat
gctggcccgcgagagacattgatgcattttgctgtgcggctgggactgctgaggttgacg
tggttcctgttgcagaagccaggtggccgcggagctctcagtatccacaaccaggaaggg
gcgacgcctgtgagcttggccttggagcgaggctatcacaagctgcaccagcttctaacc
gaggagaatgctggagaaccagactcctggagcagtttatcctatgaaataccgtatgga
gactgttctgtgaggcatcatcgagagttggacatctatacattaacctctgagtctgat
tcacatcatgaacacccatttcctggagacggttgcactggaccaatttttaaacttatg
aacatccaacagcaactaatgaaaacaaacctcaagcagatggacagtcttatgccctta
atgatgacagcacaggatccttccagtgccccagagacagatggccagtttcttccctgt
gcaccggagcccacggaccctcagcgactttcttcttctgaagagactgagagcactcag
tgctgcccagggagccctgttgcacagactgaaagtccctgtgatttgtcaagcatagtt
gaggaggagaatacagaccgttcctgtaggaagaaaaataaaggcgtggaaagaaaaggg
gaagaggtggagccagcacctattgtggactctggaactgtatctgatcaagacagctgc
cttcagagcttgcctgattgtggagtaaagggcacggaaggcctttcgtcctgtggaaac
agaaatgaagaaactggaacaaaatcttctggaatgcccacagaccaggagtccctgagc
agtggagatgctgtgcttcagagagacttggtcatggagccaggcacagcccagtattcc
tctggaggtgaactgggaggcatttcaacaacaaatgtcagtaccccagacactgcaggg
gaaatggaacatgggctcatgaacccagatgccactgtttggaagaatgtgcttcaggga
ggggaaagtacaaaggaaagatttgagaactctaatattggcacagctggagcctctgac
gtgcacgtcacaagtaagcctgtggataaaatcagtgttccaaactgtgcccctgctgcc
agttccctggatggtaacaaacctgctgagtcttcacttgcatttagtaatgaagaaacc
tccactgaaaaaacagcagaaacggaaacttcacgaagtcgtgaggagagtgctgatgct
ccagtagatcagaattctgtggtgattccagctgctgcaaaagacaagatttcagatgga
ttagaaccttatactctcttagcagcaggcataggtgaggcaatgtcaccctcagattta
gcccttcttgggctggaagaagatgtaatgccacaccagaactcagaaacaaattcatct
catgctcaaagccaaaagggcaaatcctcacccatttgttctacaactggagacgataaa
ctttgtgcagactctgcatgtcaacagaacacagtgacttctagtggcgatttggttgca
aaactgtgtgataacatagttagcgagtccgaaagcaccacagcaaggcaacccagctca
caagatccacccgatgcctcccactgtgaagacccacaggctcatacagtcacctctgac
cctgtaagggatacccaggaacgtgcggatttttgtcctttcaaagtggtggataacaaa
ggccaacgaaaagatgtgaaactagataaacctttaacaaatatgcttgaggtggtttca
catccacatccagttgtccctaaaatggagaaagaactggtgccagaccaggcagtaata
tcagacagtactttctctctggcaaacagtccaggcagtgaatcagtaaccaaggatgac
gcactttcttttgtcccctcccagaaagaaaagggaacagcaactcctgaactacataca
gctacagattatagagatggcccagatggaaattcgaatgagcctgatacgcggccacta
gaagacagggcagtaggcctgtccacatcctccactgctgcagagcttcagcacgggatg
gggaataccagtctcacaggacttggtggagagcatgagggtcccgcccctccagcaatc
ccagaagctctgaatatcaaggggaacactgactcttccctgcaaagtgtgggtaaggcc
actttggctttagattcagttttgactgaagaaggaaaacttctggtggtttcagaaagc
tctgcagctcaggaacaagataaggataaagcggtgacctgttcctctattaaggaaaat
gctctctcttcaggaactttgcaggaagagcagagaacaccacctcctggacaagatact
caacaatttcatgaaaaatcaatctcagctgactgtgccaaggacaaagcacttcagcta
agtaattcaccgggtgcatcctctgcctttcttaaggcagaaactgaacataacaaggaa
gtggccccacaagtctcactgctgactcaaggtggggctgcccagagcctggtgccacca
ggagcaagtctggccacagagtcaaggcaggaagccttgggggcagagcacaacagctcc
gctctgttgccatgtctgttgccagatgggtctgatgggtccgatgctcttaactgcagt
cagccttctcctctggatgttggagtgaagaacactcaatcccagggaaaaactagtgcc
tgtgaggtgagtggagatgtgacggtggatgttacaggggttaatgctctacaaggtatg
gctgagcccagaagagagaatatatcacacaacacccaagacatcctgattccaaacgtc
ttgttgagccaagagaagaatgccgttctaggtttgccagtggctctacaggacaaagct
gtgactgacccacagggagttggaaccccagagatgatacctcttgattgggagaaaggg
aagctggagggagcagaccacagctgtaccatgggtgacgctgaggaagcccaaatagac
gatgaagcacatcctgtcctactgcagcctgttgccaaggagctccccacagacatggag
ctctcagcccatgatgatggggccccagctggtgtgagggaagtcatgcgagccccgcct
tcaggcagggaaaggagcactccctctctaccttgcatggtctctgcccaggacgcacct
ctgcctaagggggcagacttgatagaggaggctgccagccgtatagtggatgctgtcatc
gaacaagtcaaggccgctggagcactgcttactgagggggaggcctgtcacatgtcactg
tccagccctgagttgggtcctctcactaaaggactagagagtgcttttacagaaaaagtg
agtactttcccacctggggagagcctaccaatgggcagtactcctgaggaagccacgggg
agccttgcaggatgttttgctggaagggaggagccagagaagatcattttacctgtccag
gggcctgagccagcagcagaaatgccagacgtgaaagctgaagatgaagtggattttaga
gcaagttcaatttctgaagaagtggctgtagggagcatagctgctacactgaagatgaag
caaggcccaatgacccaggcgataaaccgagaaaactggtgtacaatagagccatgccct
gatgcagcatctcttctggcttccaagcagagcccagaatgtgagaacttcctggatgtt
ggactgggcagagagtgtacctcaaaacaaggtgtacttaaaagagaatctgggagtgat
tctgacctctttcactcacccagtgatgacatggacagcatcatcttcccaaagccagag
gaagagcatttggcctgtgatatcaccggatccagttcatccaccgatgacacggcttca
ctggaccgacattcttctcatggcagtgatgtgtctctctcccagattttaaagccaaac
aggtcaagagatcggcaaagccttgatggattctacagccatgggatgggagctgagggt
cgagaaagtgagagtgagcctgctgacccaggcgacgtggaggaggaggagatggacagt
atcactgaagtgcctgcaaactgctctgtcctaaggagctccatgcgctctctttctccc
ttccggaggcacagctgggggcctgggaaaaatgcagccagcgatgcagaaatgaaccac
cggagttcaatgcgagttcttggggatgttgtcaggagacctcccattcataggagaagt
ttcagtctagaaggcttgacaggaggagctggtgtcggaaacaagccatcctcatctcta
gaagtaagctctgcaaatgccgaagagctcagacacccattcagtggtgaggaacgggtt
gactctttggtgtcactttcagaagaggatctggagtcagaccagagagaacataggatg
tttgatcagcagatatgtcacagatctaagcagcagggatttaattactgtacatcagcc
atttcctctccattgacaaaatccatctcattaatgacaatcagccatcctggattggac
aattcacggcccttccacagtaccttccacaataccagtgctaatctgactgagagtata
acagaagagaactataatttcctgccacatagcccctccaagaaagattctgaatggaag
agtggaacaaaagtcagtcgtacattcagctacatcaagaataaaatgtctagcagcaag
aagagcaaagaaaaggaaaaagaaaaagataagattaaggagaaggagaaagattctaaa
gacaaggagaaagataagaagactgtcaacgggcacactttcagttccattcctgttgtg
ggtcccatcagctgtagccagtgtatgaagcccttcaccaacaaagatgcctatacttgt
gcaaattgcagtgcttttgtccacaaaggctgccgagaaagtctagcctcctgtgcaaag
gtcaaaatgaagcagcccaaagggagccttcaggcacatgacacatcatcactgcccacg
gtcattatgagaaacaagccctcacagcccaaggagcgtcctcggtccgcagtcctcctg
gtggatgaaaccgctaccaccccaatatttgccaatagacgatcccagcagagtgtctcg
ctctccaaaagtgtctccatacagaacattactggagttggcaatgatgagaacatgtca
aacacctggaaattcctgtctcattcaacagactcactaaataaaatcagcaaggtcaat
gagtcaacagaatcacttactgatgagggagtaggtacagacatgaatgaaggacaacta
ctgggagactttgagattgagtccaaacagctggaagcagagtcttggagtcggataata
gacagcaagtttctaaaacagcaaaagaaagatgtggtcaaacggcaagaagtaatatat
gagttgatgcagacagagtttcatcatgtccgcactctcaagatcatgagtggtgtgtac
agccaggggatgatggcggatctgctttttgagcagcagatggtagaaaagctgttcccc
tgtttggatgagctgatcagtatccatagccaattcttccagaggattctggagcggaag
aaggagtctctggtggataaaagtgaaaagaactttctcatcaagaggataggggatgtg
cttgtaaatcagttttcaggtgagaatgcagaacgtttaaagaagacatatggcaagttt
tgtgggcaacataaccagtctgtaaactacttcaaagacctttatgccaaggataagcgt
tttcaagcctttgtaaagaagaagatgagcagttcagttgttagaaggcttggaattcca
gagtgcatattgcttgtaactcagcggattaccaagtacccagttttattccaaagaata
ttgcagtgtaccaaagacaatgaagtggagcaggaagatctagcacagtccttgagcctg
gtgaaggatgtgattggagctgtagacagcaaagtggcaagttatgaaaagaaagtgcgt
ctcaatgagatttatacaaagacagatagcaagtcaatcatgaggatgaagagtggtcag
atgtttgccaaggaagatttgaaacggaagaagcttgtacgtgatgggagtgtgtttctg
aagaatgcagcaggaaggttgaaagaggttcaagcagttcttctcactgacattttagtt
ttccttcaagaaaaagaccagaagtacatctttgcatcattggaccagaagtcaacagtg
atctctttaaagaagctgattgtgagagaagtggcacatgaggagaaaggtttattcctg
atcagcatggggatgacagatccagagatggtagaagtccatgccagctccaaagaggaa
cgaaacagctggattcagatcattcaggacacaatcaacaccctgaacagagatgaagat
gaaggaattcctagtgagaatgaggaagaaaagaaaatgttggacaccagagcccgagaa
ttaaaagaacaacttcaccagaaggaccaaaaaatcctactcttgttggaagagaaggag
atgattttccgggacatggctgagtgcagcacccctctcccagaggattgctccccaaca
catagccctagagttctcttccgctccaacacagaagaggctctcaaaggaggaccttta
atgaaaagtgcaataaatgaggtggagatccttcagggtttggtgagtggaaatctggga
ggcacacttgggccgactgtcagcagccccattgagcaagatgtggtcggtcccgtttcc
ctgccccggagagcagagacctttggaggatttgacagccatcagatgaatgcttcaaaa
ggaggcgagaaggaagagggagatgatggccaagatcttaggagaacggaatcagatagt
ggcctaaaaaagggtggaaatgctaacctggtatttatgcttaaaagaaacagtgagcag
gttgtccagagcgttgttcatctctacgagctcctcagcgctctgcagggtgtggtgctg
cagcaggacagctacattgaggaccagaaactggtgctgagcgagagggcgctcactcgc
agcttgtcccgcccgagctccctcattgagcaggagaagcagcgcagcctggagaagcag
cgccaggacctggccaacctgcagaagcagcaggcccagtacctcgaggagaagcgcagg
cgcgagcgtgagtgggaagctcgtgagagggagctgcgggagcgggaggccctcctggcc
cagcgcgaggaggaggtgcagcaggggcagcaggacctggaaaaggagcgggaggagctc
cagcagaagaagggcacataccagtatgacctggagcgactgcgtgctgcccagaaacag
cttgagagggaacaggagcagctgcgccgggaggcagagcggctcagccagcggcagaca
gaacgggacctgtgtcaggtttcccatccacataccaagctgatgaggatcccatcgttc
ttccccagtcctgaggagcccccctcgccatctgcaccttccatagccaaatcagggtca
ttggactcagaactttcagtgtccccaaaaaggaacagcatctctcggacacacaaagat
aaggggccttttcacatactgagttcaaccagccagacaaacaaaggaccagaagggcag
agccaggcccctgcgtccacctctgcctctacccgcctgtttgggttaacaaagccaaag
gaaaagaaggagaaaaaaaagaagaacaaaaccagccgctctcagcccggtgatggtccc
gcgtcagaagtatcagcagagggtgaagagatcttctgctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (53)   
   KEGG ORTHOLOGY (1)   
   RefGene (43)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (65)   
   RefSeq(nuc) (5)   
   GenBank (30)   
   EMBL (30)   
3D Structure (5)   
   PDB (5)   
Protein domain (8)   
   Pfam (8)   
All databases (142)   

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