KEGG   Homo sapiens (human): 11255
Entry
11255             CDS       T01001                                 
Symbol
HRH3, GPCR97, HH3R
Name
(RefSeq) histamine receptor H3
  KO
K04151  histamine receptor H3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Bavisant (DG02043): D09870 D09871
Betahistine (DG01004): D01592<JP> D03102 D07522
Cipralisant maleate: D03518
Histamine: D08040<US>
Histamine phosphate: D04445<US>
Irdabisant (DG01330): D10128 D10129
Pitolisant (DG03021): D10749 D11490<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    11255 (HRH3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    11255 (HRH3)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Biogenic amine
   Histamine
    11255 (HRH3)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx DUF621
Other DBs
NCBI-GeneID: 11255
NCBI-ProteinID: NP_009163
OMIM: 604525
HGNC: 5184
Ensembl: ENSG00000101180
UniProt: Q9Y5N1
Structure
Position
20:complement(62214960..62220278)
AA seq 445 aa
MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAA
GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSV
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
RAFTKLLCPQKLKIQPHSSLEHCWK
NT seq 1338 nt   +upstreamnt  +downstreamnt
atggagcgcgcgccgcccgacgggccgctgaacgcttcgggggcgctggcgggcgaggcg
gcggcggcgggcggggcgcgcggcttctcggcagcctggaccgcggtgctggccgcgctc
atggcgctgctcatcgtggccacggtgctgggcaacgcgctggtcatgctcgccttcgtg
gccgactcgagcctccgcacccagaacaacttcttcctgctcaacctcgccatctccgac
ttcctcgtcggcgccttctgcatcccactgtatgtaccctacgtgctgacaggccgctgg
accttcggccggggcctctgcaagctgtggctggtagtggactacctgctgtgcacctcc
tctgccttcaacatcgtgctcatcagctacgaccgcttcctgtcggtcacccgagcggtc
tcataccgggcccagcagggtgacacgcggcgggcagtgcggaagatgctgctggtgtgg
gtgctggccttcctgctgtacggaccagccatcctgagctgggagtacctgtccgggggc
agctccatccccgagggccactgctatgccgagttcttctacaactggtacttcctcatc
acggcttccaccctggagttctttacgcccttcctcagcgtcaccttctttaacctcagc
atctacctgaacatccagaggcgcacccgcctccggctggatggggctcgagaggcagcc
ggccccgagccccctcccgaggcccagccctcaccacccccaccgcctggctgctggggc
tgctggcagaaggggcacggggaggccatgccgctgcacaggtatggggtgggtgaggcg
gccgtaggcgctgaggccggggaggcgaccctcgggggtggcggtgggggcggctccgtg
gcttcacccacctccagctccggcagctcctcgaggggcactgagaggccgcgctcactc
aagaggggctccaagccgtcggcgtcctcggcctcgctggagaagcgcatgaagatggtg
tcccagagcttcacccagcgctttcggctgtctcgggacaggaaagtggccaagtcgctg
gccgtcatcgtgagcatctttgggctctgctgggccccatacacgctgctgatgatcatc
cgggccgcctgccatggccactgcgtccctgactactggtacgaaacctccttctggctc
ctgtgggccaactcggctgtcaaccctgtcctctaccctctgtgccaccacagcttccgc
cgggccttcaccaagctgctctgcccccagaagctcaaaatccagccccacagctccctg
gagcactgctggaagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (12)   
   KEGG DRUG (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (27)   
   RefSeq(nuc) (5)   
   GenBank (11)   
   EMBL (11)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (78)   

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