KEGG   Homo sapiens (human): 11274
Entry
11274             CDS       T01001                                 
Symbol
USP18, ISG43, PTORCH2, UBP43
Name
(RefSeq) ubiquitin specific peptidase 18
  KO
K11846  ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]
Organism
hsa  Homo sapiens (human)
Network
nt06518  JAK-STAT signaling
  Element
N01560  Regulation of type I interferon to Jak-STAT signaling pathway, USP18
Disease
H00840  Pseudo-TORCH syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    11274 (USP18)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    11274 (USP18)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     11274 (USP18)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   11274 (USP18)
Ubiquitin system [BR:hsa04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    11274 (USP18)
SSDB
Motif
Pfam: UCH UCH_1
Other DBs
NCBI-GeneID: 11274
NCBI-ProteinID: NP_059110
OMIM: 607057
HGNC: 12616
Ensembl: ENSG00000184979
UniProt: Q9UMW8
Position
22:18150170..18177397
AA seq 372 aa
MSKAFGLLRQICQSILAESSQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNI
GQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRP
LELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRVKDSLICVD
CAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFCENCGKKTRGK
QVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRESCDAEEQSGG
QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQE
TAYLLVYMKMEC
NT seq 1119 nt   +upstreamnt  +downstreamnt
atgagcaaggcgtttgggctcctgaggcaaatctgtcagtccatcctggctgagtcctcg
cagtccccggcagatcttgaagaaaagaaggaagaagacagcaacatgaagagagagcag
cccagagagcgtcccagggcctgggactaccctcatggcctggttggtttacacaacatt
ggacagacctgctgccttaactccttgattcaggtgttcgtaatgaatgtggacttcacc
aggatattgaagaggatcacggtgcccaggggagctgacgagcagaggagaagcgtccct
ttccagatgcttctgctgctggagaagatgcaggacagccggcagaaagcagtgcggccc
ctggagctggcctactgcctgcagaagtgcaacgtgcccttgtttgtccaacatgatgct
gcccaactgtacctcaaactctggaacctgattaaggaccagatcactgatgtgcacttg
gtggagagactgcaggccctgtatacgatccgggtgaaggactccttgatttgcgttgac
tgtgccatggagagtagcagaaacagcagcatgctcaccctcccactttctctttttgat
gtggactcaaagcccctgaagacactggaggacgccctgcactgcttcttccagcccagg
gagttatcaagcaaaagcaagtgcttctgtgagaactgtgggaagaagacccgtgggaaa
caggtcttgaagctgacccatttgccccagaccctgacaatccacctcatgcgattctcc
atcaggaattcacagacgagaaagatctgccactccctgtacttcccccagagcttggat
ttcagccagatccttccaatgaagcgagagtcttgtgatgctgaggagcagtctggaggg
cagtatgagctttttgctgtgattgcgcacgtgggaatggcagactccggtcattactgt
gtctacatccggaatgctgtggatggaaaatggttctgcttcaatgactccaatatttgc
ttggtgtcctgggaagacatccagtgtacctacggaaatcctaactaccactggcaggaa
actgcatatcttctggtttacatgaagatggagtgctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (25)   
   RefSeq(nuc) (3)   
   GenBank (11)   
   EMBL (11)   
Protein domain (2)   
   Pfam (2)   
All databases (63)   

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