KEGG   Homo sapiens (human): 11315
Entry
11315             CDS       T01001                                 
Symbol
PARK7, DJ-1, DJ1, GATD2, HEL-S-67p
Name
(RefSeq) Parkinsonism associated deglycase
  KO
K05687  protein DJ-1 [EC:3.5.1.124]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05012  Parkinson disease
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06463  Parkinson disease
nt06466  Pathways of neurodegeneration
  Element
N01051  Mutation-inactivated DJ1 to intrinsic apoptotic pathway
N01057  Mutation-inactivated DJ1 to FAS-JNK signaling patwhay
N01058  Mutation-inactivated DJ1 to to p53-mediated transcription
N01059  Mutation-inactivated DJ1 to KEAP1-NRF2 signaling pathway
Disease
H00057  Parkinson disease
H01600  Parkinsonian syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    11315 (PARK7)
   05022 Pathways of neurodegeneration - multiple diseases
    11315 (PARK7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    11315 (PARK7)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    11315 (PARK7)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.124  protein deglycase
     11315 (PARK7)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C56: PfpI endopeptidase family
   11315 (PARK7)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   11315 (PARK7)
SSDB
Motif
Pfam: DJ-1_PfpI ThiJ_like GATase_3 LPD16
Other DBs
NCBI-GeneID: 11315
NCBI-ProteinID: NP_001116849
OMIM: 602533
HGNC: 16369
Ensembl: ENSG00000116288
UniProt: Q99497 V9HWC2
Structure
Position
1:7961711..7985505
AA seq 189 aa
MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLED
AKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFG
SKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQ
VKAPLVLKD
NT seq 570 nt   +upstreamnt  +downstreamnt
atggcttccaaaagagctctggtcatcctggctaaaggagcagaggaaatggagacggtc
atccctgtagatgtcatgaggcgagctgggattaaggtcaccgttgcaggcctggctgga
aaagacccagtacagtgtagccgtgatgtggtcatttgtcctgatgccagccttgaagat
gcaaaaaaagagggaccatatgatgtggtggttctaccaggaggtaatctgggcgcacag
aatttatctgagtctgctgctgtgaaggagatactgaaggagcaggaaaaccggaagggc
ctgatagccgccatctgtgcaggtcctactgctctgttggctcatgaaataggttttgga
agtaaagttacaacacaccctcttgctaaagacaaaatgatgaatggaggtcattacacc
tactctgagaatcgtgtggaaaaagacggcctgattcttacaagccgggggcctgggacc
agcttcgagtttgcgcttgcaattgttgaagccctgaatggcaaggaggtggcggctcaa
gtgaaggctccacttgttcttaaagactag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (6)   
   KEGG NETWORK (6)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (17)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (22)   
   RefSeq(nuc) (4)   
   GenBank (9)   
   EMBL (9)   
3D Structure (64)   
   PDB (64)   
Protein domain (4)   
   Pfam (4)   
All databases (140)   

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